Results 51 to 60 of about 103,793 (266)

Fermentation and Quality Characteristics of Cheonggukjang Fermented with Bacillus subtilis BC-P1 [PDF]

The Korean Journal of Microbiology, 2013
The object of this study was to improve the quality of Cheonggukjang with new starter, Bacillus subtilis BC-P1. Twenty strains were isolated from the commercial cheonggukjang and 1 Bacillus strain (BC-P1) with protease activity was selected. The 16S rRNA gene sequence revealed that the BC-P1 was closely related to B. subtilis with 99% homology.
Sung-Yong Park, Mi-Ae Bang, Boung-Jun Oh, Jeong-Hoon Park, Won-Seob Song, Kyung-Min Choi, Eui-Su Choung, Hee-Ock Boo, Seung-Sik Cho   +8 more
openaire   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Sequential consumption of sauce- and elegant-flavor baijiu enhances post-drinking comfort: a randomized crossover study in Guangdong, China

Applied Food Research
Baijiu, a traditional Chinese distilled spirit, exhibits diverse flavor profiles that may influence post-drinking comfort. We tested whether consuming sauce‐flavor baijiu followed by elegant-flavor baijiu enhances physiological, cognitive, and emotional ...
Yu Fu, Jianan Liu, Guoliang He, Shaohui Fan, Deliang Wang, Cheng Wang   +5 more
doaj   +1 more source

Changes in the fermentation products, taxonomic and functional profiles of microbiota during high-moisture sweet sorghum silage fermentation

Frontiers in Microbiology, 2022
The purpose of this study was to evaluate the fermentation quality, microbial community, and functional shifts of sweet sorghum during ensiling. The high-moisture sweet sorghum (SS) was naturally ensiled for 1, 3, 7, 15, 30, and 60 days. After 60 days of
Jie Zhao, Xue-Jing Yin, Si-Ran Wang, Jun-Feng Li, Zhi-Hao Dong, Tao Shao   +5 more
doaj   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

Bacterial community in homemade kimchi and probiotic characterization of Lactiplantibacillus plantarum HQ04

Frontiers in Microbiology
Homemade fermented kimchi is rich in microbial communities and is regarded as an important source of probiotics. In this study, the bacterial community diversity of 40 kimchi samples from Yibin City, China, was analyzed using high-throughput sequencing ...
Wei Zhao, Wei Zhao, Meilin Chen, Yixuan Zhang, Yiping Fan, Pinyao Zhao, Ling Zhou, Weimin Ouyang, Jie Wang, Jie Wang   +9 more
doaj   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Quality Aspects of Rice Based Fermented Beverage [PDF]

Biomedical Journal of Scientific & Technical Research, 2021
Background: Cereal grains are one of the richest sources of important dietary fibers, proteins, vitamins, minerals, antioxidants, and other phytochemicals. However, flat flavor and poor sensorial properties make them less preferable to be consumed as raw.
openaire   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source