Mechanistic Insight into the Enzymatic Reduction of Truncated Hemoglobin N of Mycobacterium tuberculosis: role of the CD loop and pre-A Motif in electron cycling [PDF]
Background: The HbN of Mycobacterium tuberculosis carries a potent nitric-oxide dioxygenase activity despite lacking a reductase domain. Results: The NADH-ferredoxin reductase system acts as an efficient partner for the reduction of HbN.
Bidon Chanal, Axel+12 more
core +2 more sources
Evolutionary Relationships Between Low Potential Ferredoxin and Flavodoxin Electron Carriers
Proteins from the ferredoxin (Fd) and flavodoxin (Fld) families function as low potential electrical transfer hubs in cells, at times mediating electron transfer between overlapping sets of oxidoreductases.
Ian J. Campbell+5 more
doaj +1 more source
Ferredoxin Gene Mutation in Iranian Trichomonas vaginalis Isolates
Background: Trichomonas vaginalis causes trichomoniasis and metronidazole is its chosen drug for treatment. Ferredoxin has role in electron transport and carbohydrate metabolism and the conversion of an inactive form of metronidazole (CO) to its active ...
Soudabeh Heidari+6 more
doaj +2 more sources
Towards the spatial resolution of metalloprotein charge states by detailed modeling of XFEL crystallographic diffraction. [PDF]
Oxidation states of individual metal atoms within a metalloprotein can be assigned by examining X-ray absorption edges, which shift to higher energy for progressively more positive valence numbers.
Holton, James M+3 more
core +2 more sources
NADP(H) allosterically regulates the interaction between ferredoxin and ferredoxin‐NADP+ reductase
Ferredoxin‐NADP+ reductase (FNR) in plants receives electrons from ferredoxin (Fd) at the end of the photosynthetic electron transfer chain and converts NADP+ to NADPH. The interaction between Fd and FNR in plants was previously shown to be attenuated by
Yoko Kimata‐Ariga+6 more
doaj +1 more source
Electron Bifurcation and Confurcation in Methanogenesis and Reverse Methanogenesis
Reduction of the disulfide of coenzyme M and coenzyme B (CoMS–SCoB) by heterodisulfide reductases (HdrED and HdrABC) is the final step in all methanogenic pathways. Flavin-based electron bifurcation (FBEB) by soluble HdrABC homologs play additional roles
Zhen Yan, James G. Ferry
doaj +1 more source
Propionate is a microbial metabolite formed in the gastrointestinal tract, and it affects host physiology as a source of energy and signaling molecule. Despite the importance of propionate, the biochemical pathways responsible for its formation are not ...
Bo Zhang+3 more
doaj +1 more source
Biomimetic Photodiode Device with Large Photocurrent Response Using Photosynthetic Pigment-protein Complexes [PDF]
Efficient light to energy conversion was demonstrated in solid-state, lateral photodiodes device containing photosynthetic light-harvesting chlorophyll protein complexes as active materials.
Kusuma, D. Y. (Damar)+1 more
core +3 more sources
Rnf reversibly reduces NAD+ by ferredoxin coupled with Na+/H+ pumping for microbial ion gradient or reduced ferredoxin formation. Here, a cryo-EM structure provides information about the participating iron and flavin cofactors, the electron transfer ...
Stella Vitt+4 more
doaj +1 more source
Energy Conservation in Fermentations of Anaerobic Bacteria
Anaerobic bacteria ferment carbohydrates and amino acids to obtain energy for growth. Due to the absence of oxygen and other inorganic electron acceptors, the substrate of a fermentation has to serve as electron donor as well as acceptor, which results ...
Wolfgang Buckel
doaj +1 more source