Results 51 to 60 of about 87,500 (232)

2013 REU Poster: Purification and Characterization of a Ferredoxin from Mycobacterium tuberculosis [PDF]

, 2013
Poster presentation at REU Summer's End Research Symposium, 2013, by REU participant Jonas A, de Oliveira, MassBay Community College - Sean Elliott group, Evan Judd lab mentorM.
de Oliveira, Jonas A.
core   +1 more source

Preliminary X-ray diffraction analysis of YqjH from Escherichia coli: a putative cytoplasmic ferri-siderophore reductase [PDF]

, 2008
YqjH is a cytoplasmic FAD-containing protein from Escherichia coli; based on homology to ViuB of Vibrio cholerae, it potentially acts as a ferri-siderophore reductase.
Andrews, Simon C., Armour, Maria, Bamford, Vicki A., Cartron, Michael, Mitchell, Sue A., Watson, Kimberly A.   +5 more
core   +2 more sources

Engineered Multifunctional Hydrogel Delivering Novel CBX7 Inhibitor Modulates Cuproptosis Via Liquid–Liquid Phase Separation to Restore Cardiac Function in Aged Myocardial Infarction

Advanced Science, EarlyView.
An age‐adapted therapy pairs δ‐Amyrenone, a CBX7 inhibitor, with an alginate hydrogel (CSAδ) to rescue infarcted elderly hearts. CSAδ disrupts CBX7–ATP7A liquid–liquid phase separation, restores ATP7A trafficking and copper efflux, suppresses cuproptosis, supplies oxygen, scavenges ROS, promotes M2 polarization, supports angiogenesis, and enhances ...
Jun Liu, Peng Qu, Jiao Shi, Tingting Liang, Yao Gu, Xue Li, Cui Ma, Danyang Zhao, Feila Liu, Qi Liang, Panke Cheng, Qian Lei   +11 more
wiley   +1 more source

Genetic Variation in Metronidazole Metabolism and Oxidative Stress Pathways in Clinical Giardia lamblia Assemblage A and B Isolates [Corrigendum]

Infection and Drug Resistance, 2021
Saghaug CS, Klotz C, Kallio JP, et al. Infect Drug Resist. 2019;12:1221–1235. The authors have advised NR-1 was used throughout the paper to denote the gene named in GiardiaDB as “Nitroreductase family protein fused to ferredoxin domain Fd ...
Saghaug CS, Klotz C, Kallio JP, Brattbakk HR, Stokowy T, Aebischer T, Kursula I, Langeland N, Hanevik K   +8 more
doaj  

Bimetallic Peroxide Nanocomposites‐Driven Redox Dyshomeostasis to Activate Sequential Cuproptosis and Pyroptosis for Amplified Tumor Immunotherapy

Advanced Science, EarlyView.
Hyaluronic acid‐modified bimetallic peroxide nanocomposites (MgO2‐CuO2@HA) are designed for synergistic tumor therapy. The nanocomposites release Mg2+, H2O2, and Cu2+ in tumor cells, induce cuproptosis via Cu+‐mediated protein aggregation, and activate pyroptosis through caspase‐1/gasdermin D pathways for inducing immunogenic cell death, collectively ...
Guanting He, Haixia Zhu, Peipei Kang, Lili Feng, Chenghao Yu, Yanlin Zhu, Bin Liu, Zhengxiao Guo, Piaoping Yang   +8 more
wiley   +1 more source

Bimetallic Nanozyme Amplifier for Synergistic Ferroptosis‐Cuproptosis and Metabolic Reprogramming to Reshape Immunosuppressive Tumor Microenvironment

Advanced Science, EarlyView.
The Bimetallic Nanozyme Amplifier (PEG@AuCZ@CC) to maximize hydrogen peroxide production and reprogram tumor metabolism from glycolysis to oxidative phosphorylation. This shift enhances ferroptotic/cuproptotic signaling cascades and creates a glucose‐enriched but lactate‐depleted tumor microenvironment (TME), effectively overcoming immune tolerance in ...
Jianzhang Luo, Kunzhao Huang, Xiaoyuan Yi, Pei Lu, Huaying Xie, Wen Li, Qingyu Zeng, Feifei He, Duo Wang, Liyan Wang   +9 more
wiley   +1 more source

Crystal structure of pectocin M1 reveals diverse conformations and interactions during its initial step via the ferredoxin uptake system

FEBS Open Bio
Pectocin M1 (PM1), the bacteriocin from phytopathogenic Pectobacterium carotovorum which causes soft rot disease, has a unique ferredoxin domain that allows it to use FusA of the plant ferredoxin uptake system.
Nawee Jantarit, Hideaki Tanaka, Yuxi Lin, Young‐Ho Lee, Genji Kurisu   +4 more
doaj   +1 more source

A Heterodimeric Reduced-Ferredoxin-Dependent Methylenetetrahydrofolate Reductase from Syngas-Fermenting Clostridium ljungdahlii

Microbiology Spectrum, 2021
The strict anaerobe Clostridium ljungdahlii can ferment CO or H2/CO2 via the Wood-Ljungdahl pathway to acetate, ethanol, and 2,3‐butanediol. This ability has attracted considerable interest, since it can be used for syngas fermentation to produce ...
Jihong Yi, Haiyan Huang, Jiyu Liang, Rufei Wang, Ziyong Liu, Fuli Li, Shuning Wang   +6 more
doaj   +1 more source

CO2-Induced Transcriptional Reorganization: Molecular Basis of Capnophillic Lactic Fermentation in Thermotoga neapolitana [PDF]

, 2020
Capnophilic lactic fermentation (CLF) is a novel anaplerotic pathway able to convert sugars to lactic acid (LA) and hydrogen using CO2 as carbon enhancer in the hyperthermophilic bacterium Thermotoga neapolitana.
Dipasquale, Laura, d’Ippolito, Giuliana, ESERCIZIO, NUNZIA, Fontana, Angelo, LANDI, SIMONE, Lanzilli, Mariamichella, Pradhan, Nirakar, VASTANO, MARCO   +7 more
core   +2 more sources

A Dynamic Gate Enables Regioselective Hydroxylation of Free Arginine by a Non‐Canonical Heme Enzyme

Advanced Science, EarlyView.
The YqcI/YcgG enzyme AglA employs a unique “sandwich” fold and a dynamic gating mechanism to selectively hydroxylate AMPn‐Arg at Nε. Site‐directed mutations reprogram regioselectivity or enable activity on free arginine by altering hydrogen‐bond networks, precisely positioning substrates.
Yuan Sun, Chao Dou, Weizhu Yan, Pengpeng Chen, Lu Zhang, Dan Zhou, Yanhui Zheng, Zhaolin Long, Shoujie Li, Xiaoqing Xu, Qiuxia Huang, Xiaofeng Zhu, Wei Cheng   +12 more
wiley   +1 more source