Results 71 to 80 of about 97,911 (315)

An Abundant and Diverse New Family of Electron Bifurcating Enzymes With a Non-canonical Catalytic Mechanism

Frontiers in Microbiology, 2022
Microorganisms utilize electron bifurcating enzymes in metabolic pathways to carry out thermodynamically unfavorable reactions. Bifurcating FeFe-hydrogenases (HydABC) reversibly oxidize NADH (E′∼−280 mV, under physiological conditions) and reduce protons
Gerrit J. Schut, Dominik K. Haja, Xiang Feng, Farris L. Poole, Huilin Li, Michael W. W. Adams   +5 more
doaj   +1 more source

NsrR from Streptomyces coelicolor is a nitric oxide-sensing [4Fe-4S] cluster protein with a specialized regulatory function [PDF]

, 2015
The Rrf2 family transcription factor NsrR controls expression of genes in a wide range of bacteria in response to nitric oxide (NO). The precise form of the NO-sensing module of NsrR is the subject of controversy because NsrR proteins containing either ...
Al-Bassam, Mahmoud, Crack, Jason, Cramer, Stephen, Dodd, Erin, Hamilton, Christopher, Holland, Ashley, Hutchings, Matthew, Johnson, Michael, Kamali, Saeed, Knowles, Felicity, Le Brun, Nick, Munnoch, John Tyson, Thomson, Andrew   +12 more
core   +1 more source

Mechanisms of Direct Electron Transfer Governed by Redox‐Active Conductive Carrier with Superior Wettability in Anaerobic Biofilms

Advanced Science, EarlyView.
A redox‐active conductive carrier of tannic acid‐modified iron‐biochar with superior wettability is demonstrated to regulate direct electron transfer at the anaerobic biofilm‐carrier interface by enhancing the cytochrome c‐mediated pathway. For the first time, integrated evidence from spectroscopy, electrochemical analyses, and metatranscriptomics ...
Junli Tian, Xiaoyuan Zhang, Lulu Xing, Bin Ji, Jinfeng Lu, Yu Liu   +5 more
wiley   +1 more source

Human Mitochondrial Ferredoxin 1 (FDX1) and Ferredoxin 2 (FDX2) Both Bind Cysteine Desulfurase and Donate Electrons for Iron–Sulfur Cluster Biosynthesis

Biochemistry, 2016
Ferredoxins play an important role as an electron donor in iron–sulfur (Fe–S) cluster biosynthesis. Two ferredoxins, human mitochondrial ferredoxin 1 (FDX1) and human mitochondrial ferredoxin 2 (FDX2), are present in the matrix of human mitochondria ...
Kai Cai, M. Tonelli, R. Frederick, J. Markley   +3 more
semanticscholar   +1 more source

Genetic Variation in Metronidazole Metabolism and Oxidative Stress Pathways in Clinical Giardia lamblia Assemblage A and B Isolates [Corrigendum]

Infection and Drug Resistance, 2021
Saghaug CS, Klotz C, Kallio JP, et al. Infect Drug Resist. 2019;12:1221–1235. The authors have advised NR-1 was used throughout the paper to denote the gene named in GiardiaDB as “Nitroreductase family protein fused to ferredoxin domain Fd ...
Saghaug CS, Klotz C, Kallio JP, Brattbakk HR, Stokowy T, Aebischer T, Kursula I, Langeland N, Hanevik K   +8 more
doaj  

Metabolic network analysis reveals microbial community interactions in anammox granules. [PDF]

, 2017
Microbial communities mediating anaerobic ammonium oxidation (anammox) represent one of the most energy-efficient environmental biotechnologies for nitrogen removal from wastewater.
Bhattacharjee, Ananda S, Goel, Ramesh, Hamilton, Joshua J, Lawson, Christopher E, McMahon, Katherine D, Noguera, Daniel R, Wu, Sha   +6 more
core   +2 more sources

Synergistic Tuning of Conformational Dynamics, Electron Tunneling, and Substrate Positioning Enhances Electron Transfer in a P450 Chimera for Calcifediol Biosynthesis

Advanced Science, EarlyView.
A synergistic electron transfer (ET) optimization strategy modulating conformational dynamics, ET pathway, and substrate orientation is proposed for self‐sufficient cytochrome P450s. Guided by this strategy, a P450 variant with improved ET and catalytic efficiency was identified, and the underlying molecular basis was revealed by computational analysis.
Ziqi Liang, Xitong Song, Shuming Cheng, Yiwen Shen, Jie Zhang, Yaru Wang, Huiying Luo, Bin Yao, Binju Wang, Tao Tu   +9 more
wiley   +1 more source

The dual effect of a ferredoxin-hydrogenase fusion protein in vivo: successful divergence of the photosynthetic electron flux towards hydrogen production and elevated oxygen tolerance

Biotechnology for Biofuels, 2016
BackgroundHydrogen photo-production in green algae, catalyzed by the enzyme [FeFe]-hydrogenase (HydA), is considered a promising source of renewable clean energy.
H. Eilenberg, I. Weiner, Oren Ben‐Zvi, Carmel Pundak, Abigail Marmari, Oded Liran, M. Wecker, Yuval Milrad, Iftach Yacoby   +8 more
semanticscholar   +1 more source

Distinct Physiological Roles of the Three Ferredoxins Encoded in the Hyperthermophilic Archaeon Thermococcus kodakarensis

mBio, 2019
Control of electron flux is critical in both natural and bioengineered systems to maximize energy gains. Both small molecules and proteins shuttle high-energy, low-potential electrons liberated during catabolism through diverse metabolic landscapes ...
Brett W. Burkhart, Hallie P. Febvre, Thomas J. Santangelo   +2 more
doaj   +1 more source

Adrenodoxin—A versatile ferredoxin [PDF]

IUBMB Life, 2012
AbstractMammalian adrenodoxin (Adx) has been known for many years as an essential electron mediator in mitochondrial cytochrome P450 systems. Because of its ability to support several cytochrome P450 enzymes, it is involved not only in adrenal steroid hormone biosynthesis but also in vitamin D and bile acid metabolism.
Kerstin Maria, Ewen, Michael, Ringle, Rita, Bernhardt   +2 more
openaire   +2 more sources