Results 121 to 130 of about 29,761,483 (233)

Astrocytic FDX1 Contributes to Copper Dyshomeostasis‐associated Synaptic Dysfunction in Depression and Is Modulated by Exercise

Advanced Science, Volume 13, Issue 50, 7 September 2026.
Chronic stress disrupts copper homeostasis and promotes copper accumulation in the prelimbic cortex, leading to astrocytic FDX1 upregulation. Elevated astrocytic FDX1 impairs calcium signaling, induces structural atrophy, and disrupts synaptic function, contributing to depressive‐like behaviors. Physical exercise reverses these alterations by restoring
Lina Gao, Rongji Hui, Zhibo Tang, Tao Feng, Zhihang Hu, Xiaoqing Zhang, Ping Jiang, Hui Zhao, Kwok‐Fai So, Tianyuan Luo, Yanzhou Chang, Lan Yan   +11 more
wiley   +1 more source

Synthesis, Characterization, and Bioactivity of a Dioxime-Based Copper(II) Complex: SOD/Catalase Mimicry, DNA/HSA Binding, and In Silico Evaluation for Cuproptosis-Mediated Anticancer Activity

Inorganics
Cisplatin’s chemotherapy is hindered by drug resistance and toxicity, making copper complexes a potential alternative. A novel copper(II) complex, [CuLBr], was synthesized from a tetradentate vicinal dioxime ligand (H2L) and characterized.
Mortaga M. Abou-Krisha, Abd El-Motaleb M. Ramadan, Heba A. Sahyon, Ahmed M. Fathy   +3 more
doaj   +1 more source

NIR‐II Light‐Triggered Electron Flow Initiates Cuproptosis‐Centered Thermoelectric‐Immunotherapy for Breast Cancer

Advanced Science, Volume 13, Issue 53, 24 September 2026.
A NIR‐II light‐activatable thermoelectric nanoreactor converts surface‐bound Cu2+ into bioactive Cu+ via directed electron flow. This spatiotemporally controlled reduction triggers potent cuproptosis and immunogenic cell death, eradicating primary tumors and, together with aPD‐1 therapy, suppressing metastases while establishing durable immune memory ...
Boyu Yuan, Qin Fan, Shushu Chu, Shining Yang, Yuechao Yang, Chenxi Zhang, Jinqiao Zhang, Xinran Qu, Yiju Wei, Xin Wang, Ziliang Dong   +10 more
wiley   +1 more source

Ferredoxin-linked chloroplast enzymes. Progress report

, 1993
This report summarizes research on ferredoxin:NADP{sup +} oxidoreductase and ferredoxin:thioredoxin reductase. One of the primary goals of the original proposal was to map the ferredoxin-binding sites on three soluble enzymes that are located in spinach ...

core   +1 more source

Hierarchical Assembly as a Design Principle: Structure–Property Relationships Linking Biological Architectures to Functional Aggregate Materials

Aggregate, Volume 7, Issue 9, September 2026.
Biological function arises from aggregates rather than from molecules. Comparing biomimetic systems on a common basis reveals three transferable design rules governing hierarchical assembly, interfacial gradients, and stimulus‐coupled anisotropy, and identifies self‐healing and single‐step multiscale integration as properties that do not transfer to ...
Nafeesa Sarfraz, Sadaf Bibi, Muhammad Ibrar Ahmed, Jawad Hussain, Shahid Iqbal, Imran Mahmood Khan, Ajayan Vinu, Ibrahim Khan   +7 more
wiley   +1 more source

Recent Advances in Metal‐Organic Framework Photo‐Electrocatalysts for the Synthesis of Ammonia

Carbon Neutralization, Volume 5, Issue 5, September 2026.
This diagram illustrates the role of Metal‐Organic Frameworks (MOFs) in the photocatalytic and electrocatalytic synthesis of ammonia, highlighting their potential as efficient catalysts for sustainable nitrogen fixation under light irradiation and electrode excitation.
Jingjing Wang, Kaiyan Shi, Zhenlin Zhao, Yafu Wang, Ke Yang, Rui Ren, Jianqi Lu, Zhencheng Feng, Xiaojun Gu, Jiangwei Zhang   +9 more
wiley   +1 more source

FDX1 downregulation activates mitophagy and the PI3K/AKT signaling pathway to promote hepatocellular carcinoma progression by inducing ROS production

Redox Biology
Background: Mitochondrial dysfunction and metabolic reprogramming can lead to the development and progression of hepatocellular carcinoma (HCC). Ferredoxin 1 (FDX1) is a small mitochondrial protein and recent studies have shown that FDX1 plays an ...
Bo Sun, Peng Ding, Yinghui Song, Jia Zhou, Xu Chen, Chuang Peng, Sulai Liu   +6 more
doaj   +1 more source

Inhibition of ferredoxin: NADP+ reductase activity by the hexacyanochromate (III) ion.

, 1986
The small inorganic complex Cr(CN)6(3-) is a clean inhibitor of the ferredoxin: NADP+ reductase-catalysed oxidation of reduced spinach ferredoxin by NADP+.
Armstrong, Fraser, Corbett, SG
core   +1 more source

Selective Formation of 1:1 Dyads of a Saddle‐Distorted Sn(IV)‐Porphyrin as an Acceptor With Donor Molecules as Axial Ligands for Photoinduced Electron Transfer

ChemPhotoChem, Volume 10, Issue 9, September 2026.
We have revealed that a novel 1:1 complex can be selectively formed with a saddle‐distorted SnIV‐dodecaphenylporphyrin, SnIV(DPP), and sterically hindered p‐ferrocenylbenzoate derivatives as electron donors and axial ligands. In the complex, the SnIV(DPP) unit works as an electron acceptor in photoinduced electron transfer, in contrast to the previous ...
Hiro Tanaka, Tomoya Ishizuka, Hiroaki Kotani, Hayato Sakai, Taku Hasobe, Takahiko Kojima   +5 more
wiley   +1 more source

Seasonal Effect of a Small Hydropower Plant on Benthic Biofilm Microbial Community Structure and Predicted Functional Potential

Ecology and Evolution, Volume 16, Issue 9, September 2026.
Biofilm microbial composition varies significantly; diversity is higher in spring and autumn. The dewatered reach shows the broadest niche and dominant stochastic assembly. Seasonal assembly shift: deterministic in summer, stochastic in winter. Nutrient cycling genes vary more among sites than seasons under SHP influence.
Huimin Gao, Sangar Khan, Xinxin Qi, Zongwei Lin, Guohao Liu, Yuanyuan Lv, Min Zhang, Zhijun Xia, Naicheng Wu   +8 more
wiley   +1 more source