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EVALUATION OF IRON ACCUMULATION DURING CHILDHOOD CANCER TREATMENT [PDF]

open access: yesHematology, Transfusion and Cell Therapy
Objective: Iron overload is a major concern in pediatric oncology, particularly with frequent blood transfusions. Although serum ferritin levels are commonly used as a marker, cardiac and hepatic T2* MRI is the gold standard for accurate assessment. This
Şule Çalışkan Kamış   +3 more
doaj   +2 more sources

Association between serum ferritin and uric acid levels and nonalcoholic fatty liver disease in the Chinese population [PDF]

open access: yesPeerJ, 2023
Background The prevalence of nonalcoholic fatty liver disease (NAFLD) is increasing worldwide. Accumulating evidence suggests that serum ferritin and uric acid (UA) are strongly associated with the risk of NAFLD, but no consensus has been reached ...
Fangli Zhou   +5 more
doaj   +2 more sources

Mitochondrial Ferritin: Its Role in Physiological and Pathological Conditions

open access: yesCells, 2021
In 2001, a new type of human ferritin was identified by searching for homologous sequences to H-ferritin in the human genome. After the demonstration that this ferritin is located specifically in the mitochondrion, it was called mitochondrial ferritin ...
Sonia Levi   +4 more
doaj   +1 more source

Ferritin Is Secreted from Primary Cultured Astrocyte in Response to Iron Treatment via TRPML1-Mediated Exocytosis

open access: yesCells, 2023
Impaired iron homeostasis has been proven to be one of the critical contributors to the pathology of Parkinson’s disease (PD). Ferritin is considered an intracellular protein responsible for storing cytosolic iron. Recent studies have found that ferritin
Xiaoqi Yu   +3 more
doaj   +1 more source

Peran Ferritin pada Stroke Iskemik Akut

open access: yesJurnal Neuroanestesi Indonesia, 2021
Stroke merupakan defisit neurologis yang terjadi karena jejas fokal akut pada sistem saraf pusat yang semata-mata terjadi karena gangguan vaskuler, termasuk infark serebri maupun perdarahan.
Lisda Amalia
doaj   +1 more source

Ferritin‐based drug delivery system for tumor therapy

open access: yesBMEMat, 2023
Ferritin has been widely used in drug delivery in recent years due to its unique spherical nanocage structure. In addition, the natural targeting and good biocompatibility of ferritin make it an excellent drug delivery system.
Zaiqian Tu   +3 more
doaj   +1 more source

H-Ferritin Is Preferentially Incorporated by Human Erythroid Cells through Transferrin Receptor 1 in a Threshold-Dependent Manner. [PDF]

open access: yesPLoS ONE, 2015
Ferritin is an iron-storage protein composed of different ratios of 24 light (L) and heavy (H) subunits. The serum level of ferritin is a clinical marker of the body's iron level.
Soichiro Sakamoto   +8 more
doaj   +1 more source

the hyphal-associated adhesin and invasin Als3 of Candida albicans mediates iron acquisition from host ferritin. [PDF]

open access: yesPLoS Pathogens, 2008
Iron sequestration by host iron-binding proteins is an important mechanism of resistance to microbial infections. Inside oral epithelial cells, iron is stored within ferritin, and is therefore not usually accessible to pathogenic microbes.
Ricardo S Almeida   +7 more
doaj   +1 more source

A ferritin from Dendrorhynchus zhejiangensis with heavy metals detoxification activity. [PDF]

open access: yesPLoS ONE, 2012
Ferritin, an iron homeostasis protein, has important functions in transition and storage of toxic metal ions. In this study, the full-length cDNA of ferritin was isolated from Dendrorhynchus zhejiangensis by cDNA library and RACE approaches.
Chenghua Li   +6 more
doaj   +1 more source

Evaluating methods and protocols of ferritin-based magnetogenetics

open access: yesiScience, 2021
Summary: FeRIC (Ferritin iron Redistribution to Ion Channels) is a magnetogenetic technique that uses radiofrequency (RF) alternating magnetic fields to activate the transient receptor potential channels, TRPV1 and TRPV4, coupled to cellular ferritins ...
Miriam Hernández-Morales   +3 more
doaj   +1 more source

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