Results 101 to 110 of about 7,994 (300)

IRF‐1 modulates hepatic ferroptosis and aggravates liver ischemia/reperfusion injury via DYRK1α

Animal Models and Experimental Medicine, EarlyView.
IRF‐1 modulates hepatic ferroptosis and aggravates liver ischemia/reperfusion injury via DYRK1α. Abstract Background The purpose is to define the contribution of the interferon regulatory factor‐1–dual‐specificity tyrosine phosphorylation‐regulated kinase 1α (IRF‐1–DYRK1α) axis to hepatocellular ferroptosis during liver ischemia/reperfusion injury ...
Jinping Zhang, Jinming Zhang, Siyuan Song, Mingyang Li, Liying Sun, Zhijun Zhu, Dongdong Lin   +6 more
wiley   +1 more source

Porcine kidney xenotransplantation: From primate models to clinical reality

Animal Models and Experimental Medicine, EarlyView.
In the face of a critical shortage of human donor kidneys for end‐stage renal disease patients, porcine kidney xenotransplantation has emerged as a viable solution. This field has navigated major hurdles, including immune rejection, physiological incompatibilities, potential biomechanical differences and the risk of cross‐species infection. To overcome
Zihang Guo, Ling Zhang, Shoulong Deng, Chuan Qin   +3 more
wiley   +1 more source

Charge-selective Permeability of Dermo-epidermal Junction: Tracer Studies with Cationic and Anionic Ferritins

, 1988
To investigate quantitatively the charge-selective permeability of the basement membrane (BM) of the dermo-epidermal junction (DEJ), tracer experiments using anionic and cationic ferritins were performed on an epidermal sheet, whose lamina densa was ...
Yaoita, Eishin, Ito, Masaaki, Kazama, Takashi, Sato, Yoshio   +3 more
core   +1 more source

Cerebrospinal Fluid from Restless Legs Syndrome Patients Reduces Iron Uptake in Blood–Brain Barrier Endothelial Cells by Disrupting the Regulation of Transferrin Receptors

Annals of Neurology, EarlyView.
Model figure of BBBECs TfR1 regulation in control and RLS: Graphical representation of TfR1 regulation in ECs by IRPs and representing it can be dysregulated by miR‐124‐3p in ECs of RLS. FPN1, ferroportin; BBBEC, blood‐brain barrier endothelial cells; IRP, iron regulatory proytein1/2; TfR1, Transferrin receptor; IRE, Iron responsive elements; Tf ...
Kondaiah Palsa, Aurosman Pappus Sahu, David B. Rye, Lynn Marie Trotti, Irina A. Elcheva, Vladimir S. Spiegelman, James R. Connor   +6 more
wiley   +1 more source

Oxidant-induced autophagy and ferritin degradation contribute to epithelial–mesenchymal transition through lysosomal iron

Journal of Inflammation Research, 2017
Apostolos Sioutas,1 Linda K Vainikka,2 Magnus Kentson,3 Sören Dam-Larsen,4 Urban Wennerström,5 Petra Jacobson,1 Hans Lennart Persson1 1Division of Respiratory Medicine, Department of Medical and Health Sciences, 2Division of Experimental ...
Sioutas A, Vainikka LK, Kentson M, Dam-Larsen S, Wennerström U, Jacobson P, Persson HL   +6 more
doaj  

Correlation of Serum Ferritin Level with Severity of Neurological Disability in Acute Ischemic Stroke – A Cross-sectional Study

Biomedical and Biotechnology Research Journal
Background: Stroke continues to be a major cause of death and disability worldwide, with ischemic stroke forming most of the cases. Early identification of reliable biomarkers can help in predicting severity and improving outcomes.
Naved Chaudhari, Vivek Pande, Arvind Agrawal, Kartik Khurana   +3 more
doaj   +1 more source

Structural and Mechanistic Studies of Prokaryotic Ferritins [PDF]

, 2018
Prokaryotic ferritins are specialised proteins used by cells to uptake, oxidize and store iron. These proteins are composed by identical subunits forming a hollow spherical structure.
Silva, Daniela Penas da
core  

Immunochemical characterization of human liver and heart ferritins with monoclonal antibodies.

, 1986
A library of 27 murine monoclonal antibodies was obtained by using human liver and heart ferritins as immunogens. The specificity of the antibodies for the two ferritins and their subunits was studied with five different methods.
De Simone F, Brocchi E, LEVI , SONIA MARIA ROSA, Luzzago A, Gamba D, Arosio P, Iacobello C, Ruggeri G, Gabri E, Capucci L   +9 more
core   +1 more source

Utility of reticulocyte hemoglobin as a new predictor of anemia in intensive care unit patients

Frontiers in Medicine
IntroductionIron deficiency and anemia are common complications in critically ill patients, particularly in the Intensive Care Unit setting (ICU), where inflammation and infection are prevalent.
Manuel De la Cruz-Garcinuño, Raúl Juárez-Vela, Raúl Juárez-Vela, Pablo Lasa-Berasain, Regina Ruiz de Viñaspre-Hernández, Michał Czapla, Michał Czapla, Lourdes García-Muñoz, Enrique Polo-Andrade, Carmen Sarmiento, Javier Rodero-Martínez, Mirian Alonso-Arias, Saray López-Tornero, Manuel Quintana-Díaz, Manuel Quintana-Díaz   +14 more
doaj   +1 more source

[Tissue and blood ferritins and isoferritins]

, 1986
International audienceFerritins which can store excess iron are localised principally in tissue. Ferritins have on apoprotein shell which is composed of 24 sub-units, from 2 types of sub-units: "H" (molecular weight about 21 000) and "L" (molecular ...
Lasne, Y., Vernet, Marc, Collombel, C., Damour, O., Dellamonica, C.   +4 more
core