Results 111 to 120 of about 10,617 (280)

Serum Ferritin as a Predictor of Hospital Mortality in Critically Ill COVID-19 Patients

open access: yesCOVID
Serum ferritin levels increase in severe COVID-19 patients. However, few data correlating the sensitivity and specificity of ferritin levels and mortality prediction in COVID-19 exist. The current study aims to investigate the sensitivity and specificity
Ferhat Soykan   +10 more
doaj   +1 more source

Comparative expression profiling reveals a role of the root apoplast in local phosphate response [PDF]

open access: yes, 2016
BACKGROUND Plant adaptation to limited phosphate availability comprises a wide range of responses to conserve and remobilize internal phosphate sources and to enhance phosphate acquisition.
Jens Müller   +5 more
core   +10 more sources

Magneto‐X Effects in Magnetic Soft Materials and Their Applications

open access: yesAdvanced Science, EarlyView.
This review systematically explores magnetic soft materials (MSMs), a novel class of composites that transform under magnetic fields. It catalogs fundamental “Magneto‐X” effects, classifies materials by their matrix and magnetic fillers, and highlights transformative applications in soft robotics, biomedical devices, flexible electronics, etc. Finally,
Ziyin Xiang   +5 more
wiley   +1 more source

Electrochemically Controlled Reconstitution of Immobilized Ferritins for Bioelectronic Applications [PDF]

open access: yes
Site-specific reconstituted nanoparticles were fabricated via electrochemically-controlled biomineralization through the immobilization of biomolecules.
Choi, Sang H.   +5 more
core   +1 more source

Iron, Oxidative Damage and Ferroptosis in Rhabdomyosarcoma. [PDF]

open access: yes, 2017
Recent data have indicated a fundamental role of iron in mediating a non-apoptotic and non-necrotic oxidative form of programmed cell death termed ferroptosis that requires abundant cytosolic free labile iron to promote membrane lipid peroxidation ...
Fanzani, Alessandro, Poli, Maura
core   +1 more source

Lactylation Reprogramming in the Bone Infection Microenvironment Identifies PGK1 K361 as a Potential Therapeutic Target for Osteogenic Dysfunction

open access: yesAdvanced Science, EarlyView.
Staphylococcus aureus (S. aureus) infection creates a high‐lactate microenvironment, promoting p300‐mediated lactylation of PGK1 at lysine 361 (K361). Lactylated PGK1 translocates to the mitochondrial outer membrane and interacts with VDAC3. This interaction triggers FtMt downregulation, iron accumulation, and excessive PINK1/Parkin‐mediated mitophagy,
Han‐jun Qin   +5 more
wiley   +1 more source

Ferroptosis: The Demise of Cells Through Phospholipid Peroxidation

open access: yesAdvanced Science, EarlyView.
The relative abundance of peroxidation‐resistant monounsaturated fatty acids (MUFAs) vs. peroxidation‐sensitive polyunsaturated fatty acids (PUFAs) incorporated into phospholipid (PL) is a key determinant of ferroptosis sensitivity, as the peroxidation of PL PUFA acyl chains (PUFA‐PL) disrupts membrane integrity, causing ferroptotic cell death ...
Shaojie Cui, Jin Ye
wiley   +1 more source

Nanozymes for Liver Disease Therapy: Advances in Catalytic Activity, Targeting Strategies, and Clinical Translation

open access: yesAdvanced Science, EarlyView.
Nanozymes, as enzyme‐mimicking nanomaterials, exhibit unique catalytic properties for the treatment of liver diseases. By regulating redox homeostasis, modulating immune responses, and enabling targeted delivery, nanozymes overcome the limitations of natural enzymes.
Xiandi Meng   +6 more
wiley   +1 more source

Meta-análisis: prevalencia de deficiencia de hierro en donantes de sangre repetitivos y asociación con sexo, 2001-2011 Meta-analysis: prevalence of iron deficiency in systematic blood donors and its association with gender

open access: yesRevista Cubana de Hematología, Inmunología y Hemoterapia, 2013
Introducción: la donación de sangre repetitiva y el sexo femenino potencian el desarrollo de deficiencia de hierro que provoca un suministro inadecuado de sangre y compromiso de la salud del donante.
Carmen Yulieth Mantilla-Gutiérrez   +1 more
doaj  

Atypical Clinical Course of Griscelli Syndrome Type 2 With Primarily Neurologic Presentation and Adult‐Onset in a 46‐Year‐Old Male

open access: yesAmerican Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Griscelli Syndrome Type 2 (GS2) is a rare autosomal recessive disorder caused by pathogenic mutations in the RAB27A gene. Typically, it is characterized by cutaneous hypopigmentation, immunodeficiency, with or without neurological abnormalities secondary to hemophagocytic lymphohistiocytosis (HLH). Without treatment, GS2 often results in fatal
Dzhoy Papingi   +6 more
wiley   +1 more source

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