Results 61 to 70 of about 87,796 (384)

Folic acid conjugated ferritins as photosensitizer carriers for photodynamic therapy.

Nanoscale, 2015
We coupled folic acid as a tumour targeting ligand to the surface of ferritins and loaded them with ZnF16Pc. The resulting nanoconjugates can efficiently hone in on 4T1 tumours in vivo, and, with photoirradiation, leading to suppressed tumour growth and ...
Zipeng Zhen, Wei Tang, Weizhong Zhang, Jin Xie   +3 more
semanticscholar   +1 more source

The thioredoxin‐like and one glutaredoxin domain are required to rescue the iron‐starvation phenotype of HeLa GLRX3 knock out cells

FEBS Letters, EarlyView.
Glutaredoxin (Grx) 3 proteins contain a thioredoxin domain and one to three class II Grx domains. These proteins play a crucial role in iron homeostasis in eukaryotic cells. In human Grx3, at least one of the two Grx domains, together with the thioredoxin domain, is essential for its function in iron metabolism.
Laura Magdalena Jordt, Manuela Gellert, Finja Zelms, Sander Bekeschus, Christopher Horst Lillig   +4 more
wiley   +1 more source

Lipid Oxidation Induced by RF Waves and Mediated by Ferritin Iron Causes Activation of Ferritin-Tagged Ion Channels

Cell Reports, 2020
Summary: One approach to magnetogenetics uses radiofrequency (RF) waves to activate transient receptor potential channels (TRPV1 and TRPV4) that are coupled to cellular ferritins.
Miriam Hernández-Morales, Trisha Shang, Jingjia Chen, Victor Han, Chunlei Liu   +4 more
doaj  

A Model of the Cellular Iron Homeostasis Network Using Semi-Formal Methods for Parameter Space Exploration

, 2012
This paper presents a novel framework for the modeling of biological networks. It makes use of recent tools analyzing the robust satisfaction of properties of (hybrid) dynamical systems.
Aisen, Alexandre Donzé, Andrews, Arosio, Chen, Chifman, Cianetti, De Domenico, Donzé, Donzé, Donzé, Dycke, Epsztejn, Erlitzki, Ezio Bartocci, Funahashi, Galaris, Granvilliers, Hunt, Jean Marc Moulis, Knutson, Luca Bortolussi, Maxima, Mayr, Moirand, Nicolas Mobilia, Omholt, Shvartsman, Wang, Weissman, Éric Fanchon   +30 more
core   +1 more source

Polydatin ameliorates ovalbumin‐induced asthma in a rat model through NCOA4‐mediated ferroautophagy and ferroptosis pathway

FEBS Open Bio, EarlyView.
In this research, a rat model of asthma was created using OVA, and polydatin served as an intervention. By inhibiting ferroautophagy mediated by NCOA4 and averting ferroptosis, polydatin has been demonstrated to reduce asthma. This work presents new ideas for investigating the mechanism of polydatin's ability to alleviate asthma, in addition to ...
Wei Li, Yuwei Tang, Wenkang Liu, Fang Fang, Jiepeng Wang, Chaoyi Fang   +5 more
wiley   +1 more source

A Protein-Based Ferritin Bio-Nanobattery

Journal of Nanotechnology, 2012
Nanostructured materials are increasingly important for the construction of electrochemical energy storage devices that will meet the needs of portable nanodevices.
Gerald D. Watt, Jae-Woo Kim, Bo Zhang, Timothy Miller, John N. Harb, Robert C. Davis, Sang H. Choi   +6 more
doaj   +1 more source

Tyr25, Tyr58 and Trp133 of Escherichia coli bacterioferritin transfer electrons between iron in the central cavity and the ferroxidase centre [PDF]

, 2017
Ferritins are 24meric proteins that overcome problems of toxicity, insolubility and poor bioavailability of iron in all types of cells by storing it in the form of a ferric mineral within their central cavities.
Abdul-Tehrani, Andrews, Andrews, Baaghil, Bauminger, Bou-Abdallah, Bradley, Bradley, Bradley, Bradley, Chaplin, Cheesman, Crow, Dimitri A. Svistunenko, Eshelman, Geoffrey R. Moore, Harrison, Hingorani, Hudson, Ito, Justin M. Bradley, Kwak, Laufberger, Lawson, Le Brun, Le Brun, Le Brun, Minnihan, Nick E. Le Brun, Pagba, Rajagopal, Reeder, Stiefel, Svistunenko, Theil, Thompson, Turano, Umena, Weeratunga, Weeratunga, Wong, Yang, Yasmin   +42 more
core   +2 more sources

BCS1L‐Associated Disease: 5′‐UTR Variant Shifts the Phenotype Towards Axonal Neuropathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives To investigate the consequences of a pathogenic missense variant (c.838C>T; p.L280F) and a 5′‐UTR regulatory variant (c.‐122G>T) in BCS1L on disease pathogenesis and to understand how regulatory variants influence disease severity and clinical presentation.
Rotem Orbach, Nunziata Maio, Russell J. Butterfield, A. Reghan Foley, Sarah Silverstein, Yan Li, Katherine Chao, Tanya J. Lehky, Abigail Potticary, Tracey A. Rouault, Sandra Donkervoort, Carsten G. Bönnemann   +11 more
wiley   +1 more source

The association between serum ferritin and blood pressure in adult women: a large cross-sectional study

Clinical and Experimental Hypertension, 2022
Background Studies on the relationships between ferritin and blood pressure remain limited, especially in adult women. The aim of the present study was to investigate the associations between serum ferritin and blood pressure among adult women.
Andong He, Xiaofeng Yang, Yuzhen Ding, Lu Sun, Meiting Shi, Ruiman Li   +5 more
doaj   +1 more source

A Cytosolic Iron Chaperone that Delivers Iron to Ferritin [PDF]

, 2008
Ferritins are the main iron storage proteins found in animals, plants and bacteria. The capacity to store iron in ferritin is essential for life in mammals, but the mechanism by which cytosolic iron is delivered to ferritin is unknown.
Bencze, Krisztina Z., Philpott, Caroline C., Shi, Haifeng, Stemmler, Timothy L.   +3 more
core   +2 more sources