Results 81 to 90 of about 87,796 (384)
Hepcidin and iron metabolism disorders in patients with chronic kidney disease [PDF]
Vojnosanitetski Pregled, 2013 Bacground/Aim. Hepcidin may play a pathogenetic role in iron metobolism disorders. The aim of this study was to determine the correlation between hepcidin concentration and parameters of iron metabolism in patients with different stage of chronic ...
Jelić Marija +8 more
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Advanced Science, EarlyView.Pinoresinol diglucoside, a bioactive component extracted from traditional Chinese medicine, attenuates cisplatin‐induced ototoxicity in vivo and in vitro. The protective effect is achieved by downregulation of Socs1. The present study is the first to investigate the expression and function of Socs1 in inner ear, which is known to promote ferroptosis ...
Yin Chen +12 more
wiley +1 more source
Advanced Science, EarlyView.CRISPR/Cas9 screening reveals PTPN2 as essential for ALK+ ALCL survival. PTPN2 regulates TFRC to promote PINK1‐PRKN mitophagy. Oral PTPN2 inhibitor ABBV‐CLS‐484 disrupts mitochondrial renewal and blocks TFRC‐mediated mitophagy to exert anti‐tumor activities, supporting clinical development for ALK+ ALCL.
Wei‐Ting Wang +11 more
wiley +1 more source
Iron at the center of ferritin, metal/oxygen homeostasis and novel dietary strategies
Biological Research, 2006 Bioiron _ central to respiration, photosynthesis and DNA synthesis and complicated by radical chemistry with oxygen _ depends on ferritin, the super family of protein nanocages (maxi-ferritins in humans, animals, plants and bacteria, and mini-ferritins ...
X LIU, K HINTZE, B LONNERDAL, EC THEIL
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Utility of reticulocyte hemoglobin as a new predictor of anemia in intensive care unit patients
Frontiers in MedicineIntroductionIron deficiency and anemia are common complications in critically ill patients, particularly in the Intensive Care Unit setting (ICU), where inflammation and infection are prevalent.
Manuel De la Cruz-Garcinuño +14 more
doaj +1 more source
Iron, Oxidative Damage and Ferroptosis in Rhabdomyosarcoma. [PDF]
, 2017 Recent data have indicated a fundamental role of iron in mediating a non-apoptotic and non-necrotic oxidative form of programmed cell death termed ferroptosis that requires abundant cytosolic free labile iron to promote membrane lipid peroxidation ...
Fanzani, Alessandro, Poli, Maura
core +1 more source
Acute Phase Proteins: Ferritin and Ferritin Isoforms [PDF]
, 2011 Ferritin is a positive acute phase reactant, exhibiting increased levels in blood during the acute phase response. Nevertheless, the precise role of ferritin as an acute phase reactant remains to be clarified. As for other acute phase proteins, ferritin is produced and secreted by hepatocytes.
Margaretha Viljoen, Alida Maria Koorts
openaire +3 more sources
Siderosomal ferritin. The missing link between ferritin and haemosiderin? [PDF]
Biochemical Journal, 1987 A minor electrophoretically fast component was found in ferritin from iron-loaded rat liver in addition to a major electrophoretically slow ferritin similar to that observed in control rats. The electrophoretically fast ferritin showed immunological identity with the slow component, but on electrophoresis in SDS it gave a peptide of 17.3 kDa, in ...
Simon C. Andrews +2 more
openaire +3 more sources
Advanced Science, EarlyView.Iron overload in ovarian endometriosis (OE) disrupts follicular function and contributes to infertility. This study maps iron‐induced cellular changes using single‐cell and spatial transcriptomics, revealing senescence phenotypes in OE patients and mouse models. Similar patterns are observed in aging ovaries, highlighting iron metabolism as a potential
Yangshuo Li +14 more
wiley +1 more source
VacciMonitor, 2022 Splenectomy is necessary in beta thalassemia major patients when the spleen becomes hyperactive, leading to extreme destruction of erythrocytes. This study assessed the ferritin effect on serum pneumococcal antibody response following pneumococcal ...
Karamatollah Rahmanian +5 more
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