Results 81 to 90 of about 23,251 (281)

A Prussian Blue Nanozyme‐Adjuvanted Vaccine Presenting Phosphocholine Antigens for Induction of Immunotolerance in Inflammatory Bowel Disease

Advanced Science, EarlyView.
ABSTRACT Inflammatory bowel disease (IBD) is a complex disorder characterized by chronic intestinal inflammation and impaired barrier function, for which effective long‐term therapies remain elusive. To address this challenge, we developed a novel nano‐vaccine that combines Prussian blue nanozymes (PBNZs) adjuvants with a ferritin carrier loaded with ...
Jingyi Sheng, Yubo Huang, Xinyue Li, Yin Liu, Yuehuang Wu, Yuxin Zhang, Ning Gu   +6 more
wiley   +1 more source

Unnatural Amino Acid and Emerging Chemistry Approaches to Map RNA–Protein Interactions

Angewandte Chemie, EarlyView.
This review highlights emerging chemistries for mapping RNA–protein interactions, including genetically encoded unnatural amino acids, novel photocrosslinkers, and non‐photoactivatable crosslinking systems. We compare their mechanisms, reactivity and applications, outlining how these next‐generation tools enable higher‐resolution, site‐specific ...
Eryn Lundrigan, Parrish Evers, Elexa Scott, John Paul Pezacki   +3 more
wiley   +2 more sources

Meta-análisis: prevalencia de deficiencia de hierro en donantes de sangre repetitivos y asociación con sexo, 2001-2011 Meta-analysis: prevalence of iron deficiency in systematic blood donors and its association with gender

Revista Cubana de Hematología, Inmunología y Hemoterapia, 2013
Introducción: la donación de sangre repetitiva y el sexo femenino potencian el desarrollo de deficiencia de hierro que provoca un suministro inadecuado de sangre y compromiso de la salud del donante.
Carmen Yulieth Mantilla-Gutiérrez, Jaiberth Antonio Cardona-Arias   +1 more
doaj  

Lactylation Reprogramming in the Bone Infection Microenvironment Identifies PGK1 K361 as a Potential Therapeutic Target for Osteogenic Dysfunction

Advanced Science, EarlyView.
Staphylococcus aureus (S. aureus) infection creates a high‐lactate microenvironment, promoting p300‐mediated lactylation of PGK1 at lysine 361 (K361). Lactylated PGK1 translocates to the mitochondrial outer membrane and interacts with VDAC3. This interaction triggers FtMt downregulation, iron accumulation, and excessive PINK1/Parkin‐mediated mitophagy,
Han‐jun Qin, Si‐ying He, Ting‐hui Xiao, Da‐mao Dai, Xin‐jia Hu, Nan Jiang   +5 more
wiley   +1 more source

Longitudinal neural connection detection using a ferritin‐encoding adeno‐associated virus vector and in vivo MRI method

, 2021
Aoling Cai, Ning Zheng, Garth J. Thompson, Yang Wu, Binbin Nie, Kunzhang Lin, Peng Su, Jinfeng Wu, Anne Manyande, Ling‐Qiang Zhu, Jie Wang, Fuqiang Xu   +11 more
openalex   +1 more source

Serum Vitamin B12, Folate, and Ferritin levels in Children and Adolescents with Anxiety Disorders; Controlled Study

, 2022
Sabide Duygu Uygun, Zeynep Göker, Fatma Karaca Kara, Özden Şükran Üneri   +3 more
openalex   +1 more source

Hetrombopag Added to Cyclosporine as the First‐Line Treatment for Patients With Non‐Severe Aplastic Anemia: A Phase 2 Multicenter Trial

American Journal of Hematology, EarlyView.
ABSTRACT Non‐severe aplastic anemia (NSAA) is a heterogeneous bone marrow failure syndrome with limited standardized treatment options. Cyclosporine A (CsA) monotherapy often yields suboptimal responses, highlighting an unmet clinical need for more effective therapies.
Lele Zhang, Ruonan Li, Qian Liang, Weiwang Li, Hong Pan, Zhen Gao, Liwei Fang, Jingyu Zhao, Xiao Yu, Zhexiang Kuang, Neng Nie, Jianping Li, Jinbo Huang, Xin Zhao, Meili Ge, Yizhou Zheng, Jun Li, Hong Zhang, Jun Shi   +18 more
wiley   +1 more source

H‐ferritin expression in astrocytes is necessary for proper oligodendrocyte development and myelination [PDF]

, 2021
Verónica T. Cheli, Diara A. Santiago González, Qiuchen Wan, Giancarlo Denaroso, Rensheng Wan, Shaina L. Rosenblum, Pablo M. Paez   +6 more
openalex   +1 more source

Identification of ferroptosis‐related genes involved in chronic obstructive pulmonary disease based on bioinformatics analysis

Animal Models and Experimental Medicine, EarlyView.
The design of the entire paper. Green part represents the bioinformatics analysis approach. Yellow part represents the ideas of animal experiment. Abstract Background Chronic obstructive pulmonary disease (COPD) is a type of chronic respiratory disease.
Xuejing Luan, Jinghui Xie, Lu Zhang, Xiao Ma, Lichangtian Jiao, Jie Zhu   +5 more
wiley   +1 more source

63 Is High Ferritin a Useful Marker for Fat Emboli Syndrome in Patients with Sickle Cell Disorders? [PDF]

, 2018
Sierra C. Simmons, Radhika Gangaraju, Jori E. May, Jill Adamski, Marisa B. Marques   +4 more
openalex   +1 more source