Results 131 to 140 of about 17,809 (256)

Insights into molecular mechanisms of disease in Neurodegeneration with Brain Iron Accumulation; unifying theories. [PDF]

, 2016
Neurodegeneration with brain iron accumulation (NBIA) is a group of disorders characterised by dystonia, parkinsonism and spasticity. Iron accumulates in the basal ganglia and may be accompanied by Lewy bodies, axonal swellings and hyperphosphorylated ...
Adibhatla, Aghajanian, Alazami, Alderson, Andrews, Balboa, Balsinde, Barbeito, Beck, Bosveld, Bras, Bras, Breus, Brissot, Broekemeier, Brunetti, Burn, Campanella, Chen, Cozzi, Crichton, Cui, Curtis, Dall'Armi, Daugherty, Davis, Deas, Dehay, Deng, Deschauer, Di Fonzo, Dick, Duran, Dusi, Eckhardt, Edvardson, Elbaz-Alon, Engel, Friedman, Fukunaga, Gadd, Gitler, Gonzalez-Cuyar, Green, Gregory, Gregory, Grünewald, Haack, Hailey, Hallgren, Hama, Hamasaki, Hartig, Hartig, Hayflick, Hayflick, Hill, Hogarth, Hong, Hortnagel, Houlden, Hönscher, Itoh, Iuso, Jana, Jenkins, Jeong, Jiang, Jin, Kaneko, Keller, Keogh, Kondo, Kono, Kotzbauer, Kruer, Kruer, Kruer, Kruer, Kurz, Kühlbrandt, Landouré, Larsson, Lei, Leonardi, Leoni, Levi, Li, Liou, Lu, Maday, Mahadevan, Malik, Mancuso, Manjithaya, Mariño, McNeill, Moreno, Morgan, Morita, Nemazanyy, Nousbeck, Oide, Ong, Paisan-Ruiz, Paisán-Ruiz, Park, Perry, Pivtoraiko, Poli, Polishchuk, Potter, Proikas-Cezanne, Ramirez, Ramonet, Rana, Riku, Ross, Ross, Rouault, Rouault, Roy, Saitsu, Scherz-Shouval, Schmidt, Schneider, Schneider, Seleznev, Shinzawa, Siudeja, Song, Strokin, Strokin, Tan, Tooze, Tsunemi, Usenovic, Vidal, Walia, Williams, Wu, Xu, Yadrick, Yang, Yoshida, Yoshida, Zhang, Zhou, Zorzi   +148 more
core   +1 more source

Die Ferroportin-Krankheit – Eine seltene Hämochromatose. Fallbericht

, 2019
47. Kongress der Deutschen Gesellschaft für Rheumatologie (DGRh), 33. Jahrestagung der Deutschen Gesellschaft für Orthopädische Rheumatologie (DGORh), 29. Jahrestagung der Gesellschaft für Kinder- und Jugendrheumatologie (GKJR)
Kayser, M, Engel, K, Fink, H, Linne, M, Unger, L   +4 more
openaire   +1 more source

Placental iron utilisation in fetal growth restriction: alterations in mitochondrial haem synthesis and iron–sulphur cluster assembly pathways

The Journal of Physiology, Volume 604, Issue 5, Page 2229-2249, 1 March 2026.
Abstract figure legend Altered iron handling and mitochondrial pathways in FGR placentas. Placental tissue from FGR pregnancies showed increased expression of iron importers, transferrin and divalent metal transporter 1, and decreased expression of the iron exporter ferroportin, suggesting that the FGR placenta is retaining iron to meet its own ...
Veronica B. Botha, Heather C. Murray, Siddharth Acharya, Kirsty G. Pringle, Roger Smith, Joshua J. Fisher   +5 more
wiley   +1 more source

Macrophage ferroportin is essential for stromal cell proliferation in wound healing

Haematologica, 2019
Iron recycling by macrophages is essential for erythropoiesis, but may also be relevant for iron redistribution to neighboring cells at the local tissue level.
Stefania Recalcati, Elena Gammella, Paolo Buratti, Andrea Doni, Achille Anselmo, Massimo Locati, Gaetano Cairo   +6 more
doaj   +1 more source

Physiological implications of NTBI uptake by T lymphocytes [PDF]

, 2014
In iron overload disorders a significant fraction of the total iron circulates in the plasma as low molecular weight complexes not bound to transferrin, known as non-transferrin-bound iron (NTBI).
Arezes, J., Carlsson, A., Costa, M., Dias, V., Oliveira, S., Pinto, J., Porto, G., Rangel, M., Rikers, Y., Vieira, I., Vos, M.   +10 more
core   +1 more source

HFE-Related Hemochromatosis May Be a Primary Kupffer Cell Disease

Biomedicines
Iron overload can lead to increased deposition of iron and cause organ damage in the liver, the pancreas, the heart and the synovium. Iron overload disorders are due to either genetic or acquired abnormalities such as excess transfusions or chronic liver
Elias Kouroumalis, Ioannis Tsomidis, Argyro Voumvouraki   +2 more
doaj   +1 more source

Inherited Disorders of Iron Overload

Frontiers in Nutrition, 2018
Dietary iron absorption and systemic iron traffic are tightly controlled by hepcidin, a liver-derived peptide hormone. Hepcidin inhibits iron entry into plasma by binding to and inactivating the iron exporter ferroportin in target cells, such as duodenal
Kostas Pantopoulos, Kostas Pantopoulos
doaj   +1 more source

The gut in iron homeostasis: role of HIF-2 under normal and pathological conditions. [PDF]

, 2013
International audienceAlthough earlier, seminal studies demonstrated that the gut per se has the intrinsic ability to regulate the rates of iron absorption, the spotlight in the past decade has been placed on the systemic regulation of iron homeostasis ...
Mastrogiannaki, Maria, Matak, Pavle, Peyssonnaux, Carole   +2 more
core   +4 more sources

High resolution preparation of monocyte-derived macrophages (MDM) protein fractions for clinical proteomics [PDF]

, 2009
Background: Macrophages are involved in a number of key physiological processes and complex responses such as inflammatory, immunological, infectious diseases and iron homeostasis.
Rita Polati, Annalisa Castagna, Alessandra Bossi, Natascia Campostrini, Federica Zaninotto, Anna Timperio, Lello Zolla, Oliviero Olivieri, Roberto Corrocher, Domenico Girelli   +9 more
core   +1 more source

Pediatric Ferroportin Disease [PDF]

Journal of Pediatric Gastroenterology and Nutrition, 2016
Galicia-Poblet, Gonzalo, Cid-París, Ester, López-Andrés, Nerea, Losada-Pajares, Alba, Jurado-López, Juan-Carlos, Moreno-Carralero, María-Isabel, Morán-Jiménez, María-Josefa   +6 more
openaire   +2 more sources