Results 101 to 110 of about 72,927 (343)
NFE2L1-mediated proteasome function protects from ferroptosis
Molecular Metabolism, 2022 Objective: Ferroptosis continues to emerge as a novel modality of cell death with important therapeutic implications for a variety of diseases, most notably cancer and degenerative diseases.
Stefan Kotschi +6 more
doaj
Ironing Out Cell Death Mechanisms [PDF]
, 2012 Historically, key cellular regulators of diverse physiological processes have been uncovered by studying the mechanisms by which chemical entities produce interesting biological phenotypes. In this issue, Dixon et al.
Pellecchia, Maurizio, Reed, John C.
core +1 more source
Ferroptosis in immunostimulation and immunosuppression
Immunological Reviews, 2023 SummaryFerroptosis is a form of iron‐dependent regulated cell death characterized by the accumulation of toxic lipid peroxides, particularly in the plasma membrane, leading to lytic cell death. While it plays a crucial role in maintaining the overall health and proper functioning of multicellular organisms, it can also contribute to tissue damage and ...
Daolin Tang, Guido Kroemer, Rui Kang
openaire +3 more sources
Advanced Materials, EarlyView.Carbon‐based piezoelectric materials are systematically categorized based on their structural and functional properties. The mechanisms of stress‐induced charge transfer are elucidated, and their applications are explored across three key domains: piezoelectric catalysis for energy conversion and environmental remediation, piezoelectric biomedical ...
Mude Zhu +3 more
wiley +1 more source
Advanced Science, EarlyView.An unprecedented high‐resolution spatial atlas of the E. multilocularis infection foci is obtained, revealing the dynamic functions of neutrophils, Spp1+ macrophages, and fibroblasts during disease progression. The transition of parasite control strategy from “active killing” to “negative segregation” by the host may provide instructive insights into ...
Zhihua Ou +35 more
wiley +1 more source
Cells, 2021 Ferroptosis is one of the recently described types of cell death which is dependent on many factors, including the accumulation of iron and lipid peroxidation. Its induction requires various signaling pathways.
Karolina Pierzynowska +3 more
doaj +1 more source
Advances in Microfluidic Cochlea‐On‐A‐Chip
Advanced Science, EarlyView.This review systematically examines diverse cell sources for inner ear organoids and outlines stepwise induction protocols. Furthermore, it discusses current applications and prospective developments of cochlea‐on‐a‐chip technologies in areas such as deafness modeling, mechanistic studies, and drug evaluation, with particular focus on gene‐therapy drug
Tian Shen +10 more
wiley +1 more source
Oncogenic senescence: a multi-functional perspective. [PDF]
, 2017 Cellular senescence is defined as an irreversible growth arrest with the acquisition of a distinctive secretome. The growth arrest is a potent anticancer mechanism whereas the secretome facilitates wound healing, tissue repair, and development.
Alimirah, Fatouma +4 more
core
Cellular SignallingFerroptosis is a novel, iron-dependent cell death characterized by the excessive accumulation of ferroptosis lipid peroxides ultimately leading to oxidative damage to the cell membrane. Iron, lipid, amino acid metabolism, and other signaling pathways all control ferroptosis.
Xiao-Qian, Liu +6 more
openaire +2 more sources
Ferroptosis: process and function [PDF]
Cell Death & Differentiation, 2016 Ferroptosis is a recently recognized form of regulated cell death. It is characterized morphologically by the presence of smaller than normal mitochondria with condensed mitochondrial membrane densities, reduction or vanishing of mitochondria crista, and outer mitochondrial membrane rupture.
Yan Yu +8 more
openaire +2 more sources