Results 141 to 150 of about 155,094 (383)
Links between Vitamin K, Ferroptosis and SARS-CoV-2 Infection [PDF]
, 2023 Jarosław Nuszkiewicz +6 more
openalex +1 more source
Advanced Science, EarlyView.This study develops gallium‐doped V2C MXene nanozymes (Ga‐V2C) to treat acetaminophen‐induced liver injury through multi‐death pathway blockade and hepatocyte regeneration. Unlike conventional single‐target therapies like N‐acetylcysteine, Ga‐V2C nanozymes enable oxidative stress suppression, apoptosis, and ferroptosis inhibition, and enhanced ...
Xiaopeng Cai +13 more
wiley +1 more source
Role of Mitochondria in Ferroptosis and Its Relationship to Tumors
Chinese Journal of Lung CancerFerroptosis is a recently discovered form of cell death that is distinct from apoptosis, characterized primarily by the accumulation of intracellular iron and increased levels of lipid peroxidation.
Zhanrui ZHANG, Hongyu LIU, Jun CHEN
doaj +1 more source
Targeting ferroptosis as a vulnerability in cancer
Nature Reviews. Cancer, 2022 Guang Lei, Zhuang Li, B. Gan
semanticscholar +1 more source
Advanced Science, EarlyView.This study reveals that the E3 ubiquitin ligase TRIM56 exacerbates neuronal ferroptosis and brain damage by mediating K48‐linked ubiquitination and degradation of KLF4, leading to suppression of the xCT/GSH/GPX4 axis. Targeting TRIM56 alleviates cerebral ischemia‐reperfusion injury in vivo and in vitro, highlighting its therapeutic potential.
Qiangping Wang +15 more
wiley +1 more source
ケミカルスクリーニングを駆使したオートファジー制御化合物の探索と、抗がん剤の薬効機序解析手法の確立 [PDF]
, 2018 筑波大学 (University of Tsukuba ...
Sano Osamu, 佐野 修
core +1 more source
Preferential Generation of 15-HETE-PE Induced by IL-13 Regulates Goblet Cell Differentiation in Human Airway Epithelial Cells [PDF]
, 2017 Type 2–associated goblet cell hyperplasia and mucus hypersecretion are well known features of asthma. 15-Lipoxygenase-1 (15LO1) is induced by the type 2 cytokine IL-13 in human airway epithelial cells (HAECs) in vitro and is increased in fresh asthmatic ...
Aldrovandi, Maceler +10 more
core +2 more sources
Ferroptosis, Metabolic Rewiring, and Endometrial Cancer [PDF]
, 2023 Eglė Žalytė
openalex +1 more source
Ferroptosis turns 10: Emerging mechanisms, physiological functions, and therapeutic applications
Cell, 2022 B. Stockwell
semanticscholar +1 more source
Advanced Science, EarlyView.Utilizing a mitochondrial double‐targeted strategy, a novel near‐infrared fluorescent probe (FTZ‐2) is established for monitoring viscosity variations in ferroptosis‐mediated drug‐induced liver injury. In summary, this work provided a practical strategy for the early diagnosis and evaluation of liver injury.
Yongqing Zhou +5 more
wiley +1 more source