Results 241 to 250 of about 147,915 (338)

Activation of GSDME by all- trans -retinal increases sensitivity to photoreceptor ferroptosis [PDF]

open access: gold
Bo Yang   +7 more
openalex   +1 more source

Fe‐S Protein FDX1 Triggers Tumor‐Intrinsic Innate Immunity via Mitochondrial Nucleic Acids Release to Orchestrate Ferroptosis in CCRCC

open access: yesAdvanced Science, EarlyView.
Restoration of the mitochondrial Fe–S protein FDX1 suppresses clear cell renal cell carcinoma by coupling ferroptosis with tumor‐intrinsic innate immune activation. FDX1 induces mitochondrial dysfunction and mtDNA/mt‐dsRNA release, activating cGAS–STING and RIG‐I/MDA5–MAVS signaling to elicit type I interferon responses, thereby promoting antigen ...
Xing Huang   +13 more
wiley   +1 more source

LuQi formula attenuates Cardiomyocyte ferroptosis via activating Nrf2/GPX4 signaling axis in heart failure

open access: hybrid
Peipei Cheng   +7 more
openalex   +1 more source

The Immune Microenvironment in Liver Cancer: From Analysis to Targeting

open access: yesAdvanced Science, EarlyView.
This review explores how smart nanomedicines overcome the immunosuppressive tumor microenvironment in liver cancer. It details targeted delivery strategies and immune reprogramming mechanisms, including remodeling abnormal physiology, modulating metabolism, and inducing immunogenic cell death. The article highlights the paradigm shift toward multimodal
Jiaming Lan   +5 more
wiley   +1 more source

Harnessing the gut microbiome to modulate ferroptosis: a metabolic strategy for the treatment of digestive tract cancers. [PDF]

open access: yesFront Immunol
Wen J   +10 more
europepmc   +1 more source

BIOM-28. FOSL2 PROMOTES FERROPTOSIS RESISTANCE IN GLIOBLASTOMA [PDF]

open access: bronze
Yanli Tan   +5 more
openalex   +1 more source

Advanced Therapeutic Approach Based on LDHs–Mimetic Oxidoreductase

open access: yesAdvanced Science, EarlyView.
Overview of Sructure, Multienzyme‐mimicking Activity and Advanced Therapeutic Approach Based on LDHs–Mimetic Oxidoreductase. Abstract Redox dysregulation is recognized as a key driver in the pathophysiology of numerous refractory diseases, contributing significantly to the progression and poor prognosis.
Kai Song   +9 more
wiley   +1 more source

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