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Antioxidant potential of ferulic acid
Free Radical Biology and Medicine, 1992Ferulic acid is a ubiquitous plant constituent that arises from the metabolism of phenylalanine and tyrosine. It occurs primarily in seeds and leaves both in its free form and covalently linked to lignin and other biopolymers. Due to its phenolic nucleus and an extended side chain conjugation, it readily forms a resonance stabilized phenoxy radical ...
Ernst Graf
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Bioavailability of Ferulic Acid
Biochemical and Biophysical Research Communications, 1998There is a wealth of evidence for the powerful antioxidant properties in vitro of flavonoid components of the diet. However, few studies have been undertaken concerning the hydroxycinnamates, major constituents of fruit, some vegetables, beverages, and grains, particularly the extent to which they are absorbed in vivo from the diet. The study described
L C, Bourne, C, Rice-Evans
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Synthesis of glyceryl ferulate by immobilized ferulic acid esterase
Biotechnology Letters, 2008Glyceryl ferulate was synthesized by the condensation of ferulic acid with glycerol using Pectinase PL "Amano" from Aspergillus niger, which contained ferulic acid esterase, to improve the water-solubility of ferulic acid. The optimum reaction medium was glycerol/0.1 M acetate buffer, pH 4.0, (98:2 v/v).
Takemasa, Matsuo +6 more
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Ferulic Acid: Signaling Pathways in Aging
Drug Research, 2023AbstractThe need for clinical remedies to the multiple age-related deficiencies in skin function brought on by extrinsic and intrinsic causes is increased by these demographic changes. Reactive oxygen species (ROS), mitochondrial deoxyribonucleic acid (mtDNA) mutations, telomere shortening, as
Deepa, Neopane +2 more
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Metabolism of ferulic acid in rats
Journal of Asian Natural Products Research, 2005Ferulic acid is the major active constituent in many natural Chinese medicinal herbs. The metabolism of ferulic acid has been investigated using solid-phase extraction and HPLC-DAD methods that were established to separate and analyze the metabolites in urine, feces and bile.
Jin-Lan, Zhang +2 more
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Oxidation of Ferulic Acid or Arabinose-Esterified Ferulic Acid by Wheat Germ Peroxidase
Journal of Agricultural and Food Chemistry, 2002The oxidation of ferulic acid (FA) or 5-O-(trans-feruloyl)-L-arabinose (EFA) by a purified wheat germ peroxidase was followed by UV spectrophotometry and high-performance liquid chromatography using an electrochemical detection. Wheat peroxidase (POD) exhibits a ping-pong bireactant mechanism forming phenoxy radicals more rapidly from FA than from EFA ...
Rebeca, Garcia +4 more
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Esterification of ferulic acid with polyols using a ferulic acid esterase from Aspergillus niger
Biochimica et Biophysica Acta (BBA) - General Subjects, 2006Commercially available enzyme preparations were screened for enzymes that have a high ability to catalyze direct ester-synthesis of ferulic acid with glycerol. Only a preparation, Pectinase PL "Amano" produced by Aspergillus niger, feruloylated glycerol under the experimental conditions.
Moriyasu, Tsuchiyama +4 more
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Ferulic acid: Pharmacological and toxicological aspects
Food and Chemical Toxicology, 2014Ferulic acid (FA) belongs to the family of phenolic acids and is very abundant in fruits and vegetables. Over the past years, several studies have shown that FA acts as a potent antioxidant by scavenging free radicals and enhancing the cell stress response through the up-regulation of cytoprotective systems, e.g. heme oxygenase-1, heat shock protein 70,
Mancuso, Cesare, Santangelo, Rosaria
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Specificity of ferulic acid (feruloyl) esterases
Biochemical Society Transactions, 1998Specificity of ferulic acid (feruloyl) esterases G. Williamson’, C. B. Faulds and P. A. Kroon Biochemistry Department, Institute of Food Research, Norwich Research Park, Colney, Norwich NR4 7UA, U.K. 205 moyl esters (manifest as a K,,, of between lop6 Feruloyl esterases are a subclass of the carboxylic ester hydrolases (EC 3.1.1.1) which hydrolyse ...
G, Williamson, C B, Faulds, P A, Kroon
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Characterization of physicochemical properties of ferulic acid
Archives of Pharmacal Research, 2003Ferulic acid (3-methoxy, 4-hydroxy cinnamic acid) is a flavoid component possessing antioxidant property. The compound is currently under development as a new drug candidate for the treatment of the dementia. The objective of this preformulation study was to determine the physicochemical properties of ferulic acid.
Young Taek, Sohn, Jin Hee, Oh
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