Results 61 to 70 of about 146,193 (269)

Born too early and too small: higher order cognitive function and brain at risk at ages 8–16 [PDF]

open access: yes, 2019
Prematurity presents a risk for higher order cognitive functions. Some of these deficits manifest later in development, when these functions are expected to mature. However, the causes and consequences of prematurity are still unclear.
Clark, Chris A.   +12 more
core   +5 more sources

Dynamics of the Mammalian Placental Metabolome in Placentogenesis and Embryonic Development

open access: yesAdvanced Science, EarlyView.
This study identifies three metabolic stages (E8.5, E9.5–10.5, E11.5–14.5) and two transition periods (E8.5–9.5, E10.5–11.5) in mouse placental development. NAD(H) emerges as a key dynamic metabolite that enhances embryonic growth through accelerated segmentation and increased proliferation of mouse embryonic stem cell (mESC)‐induced presomitic ...
Gang Chen   +11 more
wiley   +1 more source

Ultrasonic character istics and clinical significance of umbilical cord blood flow in acute fetal distress

open access: yesJournal of Acute Disease, 2016
Objective: To study ultrasonic characteristics of umbilical cord blood flow in acute fetal distress and its correlation with umbilical artery blood gas parameters, oxidative stress parameters, neonatal brain injury and myocardial injury.
Wei Dai, Yin Xu   +3 more
doaj   +1 more source

Enzymatic Remodelling of Tumour Microenvironment Enhances Anti‐CEACAM5 CAR T‐Cell Efficacy Against Colorectal Cancer

open access: yesAdvanced Science, EarlyView.
This study shows anti‐CEACAM5 CAR T‐cells are ineffective against colorectal cancer (CRC) because of CEACAM5 sequestration at intercellular junctions and the thick tumour cell glycocalyx. Enzymatic treatments of CRC cell monolayer/tissue section with trypsin or hyaluronidase restore CEACAM5 availability, enhance CAR T‐cell activation, increase ...
Debasis Banik   +13 more
wiley   +1 more source

In utero defecation: a new concept

open access: yesThe Turkish Journal of Pediatrics, 1998
According to the current concepts, the human fetus does not defecate, and passage of meconium into the amniotic fluid is an indicator of fetal distress.
A O Ciftçi, F C Tanyel
doaj  

Assessment Of Fetal Outcome In Women Undergoing Emergency Caesarean Section For Fetal Distress In Tertiary Care Hospital

open access: yesJournal of Rawalpindi Medical College
Objective: This study aims to assess the fetal outcome in terms of early neonatal mortality among women undergoing emergency caesarean section for fetal distress.
Noor Fatima   +5 more
doaj   +1 more source

Should Magnesium Sulphate Prophylaxis be Used in all Cases of Severe Preeclampsia? [PDF]

open access: yes, 2011
A case control study, undertaken in the department of Obstetrics and Gynecology in a tertiary referral centre, was designed to administer standard dose of magnesium sulphate to 50 randomly selected severely preeclamptic women in labor (Group 1). 48 women
Bhattacharya, Sohini   +4 more
core  

The Mitochondrial Guardian α‐Amyrin Mitigates Alzheimer's Disease Pathology via Modulation of the DLK‐SARM1‐ULK1 Axis

open access: yesAdvanced Science, EarlyView.
Dietary habits play a key role in chronic diseases, and higher annual consumption of fruit and vegetable may lower risk of dementia. Artificial intelligence predicts the lipid‐like compound α‐Amyrin (αA) from plants with edible peels as a drug candidate against Alzheimer's disease.
Shu‐Qin Cao   +36 more
wiley   +1 more source

Symptomatic giant left atrial aneurysm in a child : a rare entity [PDF]

open access: yes, 2010
Isolated left atrial aneurysms are rare entities in clinical practice. Usually the condition is diagnosed in the second to fourth decades of life. The presence of such lesions in the pediatric age group is scantily described.
Awasthy, Neeraj   +4 more
core   +1 more source

Disrupting the Formation of YAP Condensates Promotes the Activation of AMPKα to Inhibit the Progression of Primary Liver Cancer

open access: yesAdvanced Science, EarlyView.
This study systematically investigates the function and molecular mechanisms of YAP phase separation in multiple primary liver cancers. These findings provide novel insights into phase separation‐mediated primary liver cancer development and validate targeted disruption of this process as an effective therapeutic strategy for primary liver cancer ...
Shuang‐Zhou Peng   +7 more
wiley   +1 more source

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