Results 221 to 230 of about 832,435 (375)

Dissecting the epigenetic regulation of the fetal hemoglobin genes to unravel a novel therapeutic approach for β-hemoglobinopathies. [PDF]

Nucleic Acids Res
Amistadi S, Fontana L, Magnoni C, Felix T, Charvin MK, Martinucci P, Gautier C, Greau L, Bessières B, Antoniou P, Romano O, Allemand E, Mussolino C, Miccio A.   +13 more
europepmc   +1 more source

An α-chain modification rivals the effect of fetal hemoglobin in retarding the rate of sickle cell fiber formation. [PDF]

Sci Rep, 2023
Worth EH, Fugate MK, Grasty KC, Loll PJ, Bishop MF, Ferrone FA.   +5 more
europepmc   +1 more source

Enhancer‐dependent gene regulation in space, time, and malignancies

International Journal of Cancer, EarlyView.
Abstract Control of cell‐type‐specific gene activation requires the coordinated activity of distal regulatory elements, including enhancers, whose inputs must be temporally integrated. Dysregulation of this regulatory capacity, such as aberrant usage of enhancers, can result in malignant transformation of cells.
Belinda Blum, Victoria Dachtler, Angelika Feldmann   +2 more
wiley   +1 more source

Utilization of Fetal Hemoglobin Parameters in Predicting Clinical Severity of Sickle Cell Disease: Retrospective Study From a Tanzanian Cohort. [PDF]

J Blood Med
Haji HM, Urio F, Nkya S, Chamba C, Nasser A, Lyimo M, Ally M, Mawalla W, Jonathan A, Kidenya B, Mutagonda R, Chirande L, Ruggajo P, Ambrose E, Metta E, Balandya E, Makani J.   +16 more
europepmc   +1 more source

Spontaneous hemoperitoneum in a 29‐week pregnancy with a history of endometriosis: A case report and review of the literature

International Journal of Gynecology &Obstetrics, Volume 169, Issue 1, Page 31-37, April 2025.
Abstract Spontaneous hemoperitoneum in pregnancy (SHIP) is defined as sudden, nontraumatic intraperitoneal bleeding that occurs during pregnancy or up to 42 days postpartum. The incidence ranges between 4 and 4.9 per 100 000 births. Although seen rarely, it is associated with perinatal morbidity and mortality due to maternal hemodynamic instability ...
Shamsi Mehdiyev, Fatma Basak Tanoglu, Esma Demir Altuncu, Engin Oral   +3 more
wiley   +1 more source

A common TBP-binding site mutation elevates fetal hemoglobin levels by competitive globin switching change in β-thalassemia. [PDF]

Blood Adv
Song M, Wei X, Luo H, Wang J, Ye Y, Qin L, Niu C, Long Y, Wang X, Shao C, Yu M, Gu F, Zhang X, Xu X.   +13 more
europepmc   +1 more source

Does induction or augmentation of labor increase the risk of postpartum hemorrhage in pregnant women with anemia? A multicenter prospective cohort study in India

International Journal of Gynecology &Obstetrics, Volume 169, Issue 1, Page 299-309, April 2025.
Abstract Objective To investigate whether induction/augmentation of labor in pregnant women with anemia increases the risk of postpartum hemorrhage (PPH) and whether this risk varied by indications for labor induction/augmentation and by anemia severity in pregnancy.
Tuck Seng Cheng, Farzana Zahir, Carolin Solomi V, Ashok Verma, Sereesha Rao, Saswati Sanyal Choudhury, Gitanjali Deka, Pranabika Mahanta, Swapna Kakoty, Robin Medhi, Shakuntala Chhabra, Anjali Rani, Amrit Bora, Indrani Roy, Bina Minz, Omesh Kumar Bharti, Rupanjali Deka, Charles Opondo, David Churchill, Marian Knight, Jennifer J. Kurinczuk, Manisha Nair   +21 more
wiley   +1 more source

Vulnerable newborn types: Analysis of population‐based registries for 165 million births in 23 countries, 2000–2021

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView., 2023
Abstract Objective To examine the prevalence of novel newborn types among 165 million live births in 23 countries from 2000 to 2021. Design Population‐based, multi‐country analysis. Setting National data systems in 23 middle‐ and high‐income countries. Population Liveborn infants.
Lorena Suárez‐Idueta, Judith Yargawa, Hannah Blencowe, Ellen Bradley, Yemisrach B. Okwaraji, Veronica Pingray, Luz Gibbons, Adrienne Gordon, Kara Warrilow, Enny S. Paixao, Ila Rocha Falcão, Sarka Lisonkova, Qi Wen, Francisco Mardones, Raúl Caulier‐Cisterna, Petr Velebil, Jitka Jírová, Erzsebet Horváth‐Puhó, Henrik Toft Sørensen, Luule Sakkeus, Lili Abuladze, Mika Gissler, Mohammad Heidarzadeh, Maziar Moradi‐Lakeh, Khalid A. Yunis, Ayah Al Bizri, Shamala D. Karalasingam, Ravichandran Jeganathan, Arturo Barranco, Lisa Broeders, Aimée E. van Dijk, Luis Huicho, Hugo Guillermo Quezada‐Pinedo, Kim Nail Cajachagua‐Torres, Fawziya Alyafei, Mai AlQubaisi, Geum Joon Cho, Ho Yeon Kim, Neda Razaz, Jonas Söderling, Lucy K. Smith, Jennifer Kurinczuk, Estelle Lowry, Neil Rowland, Rachael Wood, Kirsten Monteath, Isabel Pereyra, Gabriella Pravia, Eric O. Ohuma, Joy E. Lawn, the National Vulnerable Newborn Prevalence Collaborative Group and Vulnerable Newborn Measurement Core Group, Vicki Flenady, Harriet Lawford, Gabriela Cormick, Jose Belizan, Carlos Guevel, Mauricio Lima Barreto, José Acuña, Narjes Khalili, Pascale Nakad, Nurakman Binti Baharum, Jesus Felipe Gonzalez Roldan, Sonia Lopez Alvarez, Wilmer Cristobal Guzman‐Vilca, Carla Tarazona‐Meza, Rodrigo M. Carrillo‐Larco, Tawa O. Olukade, Hamdy A. Ali, Bradley N. Manktelow, Ruth J. Matthews, Elizabeth Draper, Alan Fenton, Celina Davis, Samantha Clarke, Robert E. Black, Joanne Katz, Daniel Erchick, Elizabeth Hazel, Mike Diaz, Anne C. C. Lee   +79 more
wiley   +1 more source

Fetal hemoglobin variants identified in adults through restriction endonuclease gene mapping methodology [PDF]

, 1985
T Nakatsuji, MS Burnley, T. H. J. Huisman   +2 more
openalex   +1 more source

Identification and characterization of RBM12 as a novel regulator of fetal hemoglobin expression. [PDF]

Blood Adv, 2022
Wakabayashi A, Kihiu M, Sharma M, Thrasher AJ, Saari MS, Quesnel-Vallières M, Abdulmalik O, Peslak SA, Khandros E, Keller CA, Giardine BM, Barash Y, Hardison RC, Shi J, Blobel GA.   +14 more
europepmc   +1 more source