Results 221 to 230 of about 819,369 (331)

A prime editing strategy to rewrite the γ-globin promoters and reactivate fetal hemoglobin for sickle cell disease.

Blood
Chalumeau A, Bou Dames M, Fontana L, Amistadi S, Antoniou P, Loganathan P, Mombled M, Corre G, Peterka M, Amendola M, Giovannangeli C, Maresca M, Miccio A, Brusson M.   +13 more
europepmc   +1 more source

Disrupting ZBTB7A or BCL11A binding sites reactivates fetal hemoglobin in erythroblasts from healthy and β⁰-thalassemia/HbE individuals. [PDF]

Sci Rep
Wongborisuth C, Innachai P, Saisawang C, Tubsuwan A, Jearawiriyapaisarn N, Kaewprommal P, Piriyapongsa J, Chiangjong W, Anurathapan U, Songdej D, Tangprasittipap A, Hongeng S.   +11 more
europepmc   +1 more source

δ-Aminolevulinate induces fetal hemoglobin expression by enhancing cellular heme biosynthesis

, 2019
Li Liu, Xingguo Zhu, Alexander Yu, Christina M. Ward, Betty S. Pace   +4 more
openalex   +2 more sources

Decreased fetal hemoglobin over time among youth with sickle cell disease on hydroxyurea is associated with higher urgent hospital use

Pediatric Blood & Cancer, 2016
N. Green, D. Manwani, Mahvish Qureshi, K. Ireland, Arpan A Sinha, A. Smaldone   +5 more
semanticscholar   +1 more source

The impact of low‐dose aspirin on hemoglobin levels in pregnancy: A secondary analysis of a randomized controlled trial for prevention of hypertensive disorders of pregnancy

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objectives This study evaluates the association of low‐dose aspirin (LDA) with hemoglobin (Hb) levels during pregnancy and explores how changes in Hb levels relate to hypertensive disorders of pregnancy (HDP). Methods This secondary analysis of a randomized controlled trial comprised 249 pregnant women recruited from a regional hospital in ...
N. M. Ngcobo, V. Dorsamy, C. Bagwandeen, P. Z. Mkhize, J. Moodley   +4 more
wiley   +1 more source

Fetal Hemoglobin in Preterm Infants After Resuscitation with Immediate Cord Clamping, Delayed Cord Clamping, or Cord Milking. [PDF]

Children (Basel)
Dani C, Remaschi G, Ulivi M, Monti N, Pratesi S.   +4 more
europepmc   +1 more source

Original Research: Stable expression of miR-34a mediates fetal hemoglobin induction in K562 cells

Experimental biology and medicine, 2016
C. Ward, Biaoru Li, B. Pace
semanticscholar   +1 more source

Perinatal mortality in eastern Africa: A systematic review and meta‐analysis

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Background Every day, over 5000 stillbirths and more than 6000 newborn deaths are estimated to occur worldwide, the majority in sub‐Saharan Africa and South Asia. Estimates, however, rely on data that might underestimate these deaths. Further, outside major categories such as preterm birth, infection, and complications at delivery, little is ...
Yohanis Alemeshet Asefa, Assefa Tola Gemeda, Hannah Blencowe, Nega Assefa, Lars Åke Persson, Anna C. Seale   +5 more
wiley   +1 more source

The histone deacetylase inhibitor CT-101 flips the switch to fetal hemoglobin expression in sickle cell disease mice. [PDF]

PLoS One
Takezaki M, Li B, Xu H, Patel N, Lucas R, Cerbone RE, Koti S, Hendrick CL, Junker LH, Pace BS.   +9 more
europepmc   +1 more source

Neutrophil‐to‐lymphocyte ratio at admission helps to predict the need for blood transfusion after vaginal delivery

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective This study assesses the association between complete blood count (CBC) parameters, including the neutrophil‐to‐lymphocyte ratio (NLR) and the platelet‐to‐lymphocyte ratio (PLR) and predicts the need for postpartum packed red blood cell transfusion (pRBCT).
Daniel Gabbai, Itamar Gilboa, Anat Lavie, Yariv Yogev, Emmanuel Attali   +4 more
wiley   +1 more source