Results 1 to 10 of about 850,904 (382)

Sex-Specific Effects of Nanoparticle-Encapsulated MitoQ (nMitoQ) Delivery to the Placenta in a Rat Model of Fetal Hypoxia [PDF]

Frontiers in Physiology, 2019
Pregnancy complications associated with chronic fetal hypoxia have been linked to the development of adult cardiovascular disease in the offspring. Prenatal hypoxia has been shown to increase placental oxidative stress and impair placental function in a ...
Esha Ganguly, Esha Ganguly, Esha Ganguly, Mais M. Aljunaidy, Mais M. Aljunaidy, Mais M. Aljunaidy, Raven Kirschenman, Raven Kirschenman, Floor Spaans, Floor Spaans, Jude S. Morton, Jude S. Morton, Thomas E. J. Phillips, C. Patrick Case, Christy-Lynn M. Cooke, Christy-Lynn M. Cooke, Sandra T. Davidge, Sandra T. Davidge, Sandra T. Davidge   +18 more
doaj   +3 more sources

Nucleated Red Blood Cells as a Marker of Acute and Chronic Fetal Hypoxia in a Rat Model [PDF]

Rambam Maimonides Medical Journal, 2017
Objective To examine the relationship between duration of fetal hypoxia, nucleated red blood cell (NRBC) count, and fetal growth. Methods Pregnant rats were exposed to a severe hypoxia (9.5%–10% O2) for varying time intervals (2, 6, 12, 24, 48, and ...
Victoria K. Minior, Brian Levine, Asaf Ferber, Seth Guller, Michael Y. Divon   +4 more
doaj   +3 more sources

Uterine artery blood flow, fetal hypoxia and fetal growth. [PDF]

Philos Trans R Soc Lond B Biol Sci, 2015
Evolutionary trade-offs required for bipedalism and brain expansion influence the pregnancy rise in uterine artery (UtA) blood flow and, in turn, reproductive success. We consider the importance of UtA blood flow by reviewing its determinants and presenting data from 191 normotensive (normal, n = 125) or ...
Browne VA, Julian CG, Toledo-Jaldin L, Cioffi-Ragan D, Vargas E, Moore LG.   +5 more
europepmc   +7 more sources

Fetal hypoxia results in sex- and cell type-specific alterations in neonatal transcription in rat oligodendrocyte precursor cells, microglia, neurons, and oligodendrocytes [PDF]

Cell & Bioscience, 2023
Background Fetal hypoxia causes vital, systemic, developmental malformations in the fetus, particularly in the brain, and increases the risk of diseases in later life. We previously demonstrated that fetal hypoxia exposure increases the susceptibility of
Isaac Kremsky, Qingyi Ma, Bo Li, Chiranjib Dasgupta, Xin Chen, Samir Ali, Shawnee Angeloni, Charles Wang, Lubo Zhang   +8 more
doaj   +2 more sources

Chronic fetal hypoxia and antenatal Vitamin C exposure differentially regulate molecular signalling in the lung of female lambs in early adulthood [PDF]

Frontiers in Physiology
IntroductionChronic fetal hypoxia is commonly associated with fetal growth restriction and can predispose to respiratory disease at birth and in later life. Antenatal antioxidant treatment has been investigated to overcome the effects of oxidative stress
Erin V. McGillick, Erin V. McGillick, Sandra Orgeig, Beth J. Allison, Kirsty L. Brain, Melanie R. Bertossa, Stacey L. Holman, Ashley S. Meakin, Michael D. Wiese, Youguo Niu, Nozomi Itani, Katie L. Skeffington, Christian Beck, Kimberly J. Botting-Lawford, Janna L. Morrison, Janna L. Morrison, Dino A. Giussani   +16 more
doaj   +2 more sources

Fetal hypoxia and apoptosis following maternal porcine reproductive and respiratory syndrome virus (PRRSV) infection [PDF]

BMC Veterinary Research, 2021
Background Mechanisms of fetal death following maternal PRRSV2 infection remain uncharacterized, although hypoxia from umbilical cord lesions and/or placental detachment due to apoptosis are hypothesized.
Carolina M. Malgarin, Fiona Moser, J. Alex Pasternak, Glenn Hamonic, Susan E. Detmer, Daniel J. MacPhee, John C. S. Harding   +6 more
doaj   +2 more sources

The Correlation Between Fetal Wellbeing and Umbilical Doppler Parameters in Pregnant Women with Gestational Hypertension [PDF]

International Journal of Women's Health
Hualan Lin, Meifang Shen, Dongbei Li, Qiuxia Sun, Liubing Lan Obstetrical Department, Meizhou people’s Hospital, Meizhou City, Guangdong Province, 514000, People’s Republic of ChinaCorrespondence: Liubing Lan, Obstetrical Department, Meizhou people’s ...
Lin H, Shen M, Li D, Sun Q, Lan L
doaj   +2 more sources

Hypoxia in extravillous trophoblasts links maternal obesity and offspring neurobehavior [PDF]

iScience
Summary: While maternal obesity (MO) is associated with neurobehavioral impairment (NBI) in offspring, the underlying mechanisms remain unknown. The placenta is thought to play a role in fetal programming.
Fatima Gunter-Rahman, Shayna Mallett, Frédérique White, Pierre-Étienne Jacques, Ravikiran M. Raju, Marie-France Hivert, Eunjung Alice Lee   +6 more
doaj   +2 more sources

Humans at high altitude: Hypoxia and fetal growth [PDF]

Respiratory Physiology & Neurobiology, 2011
High-altitude studies offer insight into the evolutionary processes and physiological mechanisms affecting the early phases of the human lifespan. Chronic hypoxia slows fetal growth and reduces the pregnancy-associated rise in uterine artery (UA) blood flow. Multigenerational vs.
Lorna G. Moore, Shelton M. Charles, Colleen G. Julian   +2 more
openalex   +4 more sources

Diagnostic value of combined maternal cardiac work and fetoplacental circulation parameters in detecting fetal intrauterine hypoxia in preeclamptic women [PDF]

Scientific Reports
To investigate the correlation between fetoplacental circulation and maternal left ventricular myocardial work (MW) parameters in patients with preeclampsia (PE) and the prediction of fetal hypoxia.
Jinghao Du, Jing Zhao, Wanyan LI, Lihong Wang   +3 more
doaj   +2 more sources