Advanced Science, EarlyView.This study investigates the critical mechanisms underlying pulmonary hypertension progression, with a focus on the novel role of neutrophil‐derived S100A9 in endothelial dysfunction‐mediated pulmonary vascular remodeling. By integrating human lung samples, multi‐omics analyses, animal models, and mechanistic in vitro studies, it is revealed that how ...
Yu Guo +13 more
wiley +1 more source
Role of Epidermal Growth Factor Receptor in Ovine Fetal Pulmonary Vascular Remodeling Following Exposure to High Altitude Long-Term Hypoxia [PDF]
, 2008 Lavonne Sheng +5 more
openalex +1 more source
Multiscale Organization of Neural Networks in a 3D Bioprinted Matrix
Advanced Science, EarlyView.A 3D bioprint model of primary neurons has been engineered with a millimeter‐scale functional neural network, and it recapitulates in vivo transcriptomic features under both normal and disease conditions to the greatest extent. The successful integration of mature neurons and 3D bioprinting signifies a major advance in neuroscience modeling ...
Huiyu Yang +16 more
wiley +1 more source
Prediction of intrapartum fetal hypoxia considering feature selection algorithms and machine learning models. [PDF]
Health Inf Sci Syst, 2019 Cömert Z +3 more
europepmc +1 more source
549 The effects of fetal arterial hypoxia and acidemia on placental production of adrenomedullin
, 2001 Brian Pierce +5 more
openalex +1 more source
Fetal Hypoxia Insults and Patterns of Brain Injury: Insights from Animal Models [PDF]
, 2009 Alistair J. Gunn, Laura Bennet
openalex +1 more source
A Feedback Loop Between Fatty Acid Metabolism and Epigenetics in Clear Cell Renal Carcinoma
Advanced Science, EarlyView.The current study has profiled the landscape of active enhancers in ccRCC and identified FABP5 as an oncogene. FABP5 is essential for the lipid droplet formation driven by HIFs and critical for H3K27ac and enhancer activity. The study has discovered the function of a feedback loop between epigenetics and lipid metabolism regulated by FABP5 in ccRCC ...
Zhou Ye +21 more
wiley +1 more source
Chronic fetal hypoxia disrupts the peri-conceptual environment in next-generation adult female rats. [PDF]
J Physiol, 2019 Aiken CE +9 more
europepmc +1 more source
179 Agreement between fetal pulse oximetry and fetal ECG in episodes of suspected hypoxia
, 2001 A. Luttkus +4 more
openalex +1 more source