Results 41 to 50 of about 795,751 (338)

MicroRNA-210 expression during childbirth and postpartum as a potential biomarker of acute fetal hypoxia

Biomedical Papers, 2019
Objective: To explore whether miR-210 expression can be used as a diagnostic and prognostic marker in acute fetal hypoxia. Methods: Whole blood samples of 29 women and their fetuses without hypoxia and 24 women and their fetuses with hypoxia were ...
Barbara Vonkova, Ivona Blahakova, Lukas Hruban, Petr Janku, Sarka Pospisilova   +4 more
doaj   +1 more source

Ketamine Reduces Inflammation Pathways in the Hypothalamus and Hippocampus Following Transient Hypoxia in the Late-Gestation Fetal Sheep

Frontiers in Physiology, 2019
The physiological response to hypoxia in the fetus has been extensively studied with regard to redistribution of fetal combined ventricular output and sparing of oxygen delivery to fetal brain and heart.
Eileen I. Chang, Miguel A. Zarate, Thomas J. Arndt, Elaine M. Richards, Maria B. Rabaglino, Maureen Keller-Wood, Charles E. Wood   +6 more
doaj   +1 more source

Prenatal Hypoxia and Placental Oxidative Stress: Insights from Animal Models to Clinical Evidences

Antioxidants, 2020
Hypoxia is a common form of intrauterine stress characterized by exposure to low oxygen concentrations. Gestational hypoxia is associated with the generation of reactive oxygen species.
Serena Silvestro, Valeria Calcaterra, Gloria Pelizzo, Placido Bramanti, Emanuela Mazzon   +4 more
doaj   +1 more source

A maternal high-fat diet induces fetal origins of NASH-HCC in mice

Scientific Reports, 2022
Maternal overnutrition affects offspring susceptibility to nonalcoholic steatohepatitis (NASH). Male offspring from high-fat diet (HFD)-fed dams developed a severe form of NASH, leading to highly vascular tumor formation.
Takao Takiyama, Toshihiro Sera, Masanori Nakamura, Masato Hoshino, Kentaro Uesugi, Shin-ichi Horike, Makiko Meguro-Horike, Ryoichi Bessho, Yuri Takiyama, Hiroya Kitsunai, Yasutaka Takeda, Kazuki Sawamoto, Naoto Yagi, Yuji Nishikawa, Yumi Takiyama   +14 more
doaj   +1 more source

Hypoxia and Mitochondrial Dysfunction in Pregnancy Complications

Antioxidants, 2021
Hypoxia is a common and severe stress to an organism’s homeostatic mechanisms, and hypoxia during gestation is associated with significantly increased incidence of maternal complications of preeclampsia, adversely impacting on the fetal development and ...
Xiang-Qun Hu, Lubo Zhang
doaj   +1 more source

Behavioral and neurodevelopmental outcome of children after maternal allopurinol administration during suspected fetal hypoxia: 5-year follow up of the ALLO-trial

PLoS ONE, 2018
Objective To evaluate the long-term neurodevelopmental and behavioral outcome of antenatal allopurinol treatment during suspected fetal hypoxia. Study design We studied children born from women who participated in a randomized double-blind placebo ...
J. Klumper, J. Kaandorp, E. Schuit, F. Groenendaal, C. Koopman‐Esseboom, E. Mulder, F. van Bel, M. Benders, B. Mol, R. V. van Elburg, A. Bos, J. Derks   +11 more
semanticscholar   +1 more source

Fetal blood vessel count increases in compensation of hypoxia in premature placentas [PDF]

Universa Medicina, 2015
Background Prematurity refers to live births before 37 weeks of gestation, wherein the baby is born before the body and its organ systems achieve perfect maturity, and this disorder is still a global problem.
K. Kartini, Ahmad A. Jusuf, Sri Widia A. Jusman, M. Ekawati, Ani R. Prijanti   +4 more
doaj   +1 more source

Low Fetal Resistance to Hypoxia as a Cause of Stillbirth and Neonatal Encephalopathy

Clinical and Experimental Obstetrics & Gynecology
Objective: Low fetal resistance to hypoxia is a factor in stillbirth and neonatal encephalopathy. This review examines fetal movement patterns in response to hypoxia as a predictor of the likelihood of stillbirth.
Petr Shabanov, Aleksandr Samorodov, Natalya Urakova, Evgeny Fisher, Albina Shchemeleva   +4 more
doaj   +1 more source

AMP‐activated protein kinase activator AICAR attenuates hypoxia‐induced murine fetal growth restriction in part by improving uterine artery blood flow

Journal of Physiology, 2020
Pregnancy at high altitude is associated with a greater incidence of fetal growth restriction due, in part, to lesser uterine artery blood flow. AMP‐activated protein kinase (AMPK) activation vasodilates arteries and may increase uterine artery blood ...
Sydney L. Lane, J. Houck, Alexandrea S. Doyle, E. Bales, R. Lorca, C. Julian, L. Moore   +6 more
semanticscholar   +1 more source

Fetal Cerebrovascular Maturation: Effects of Hypoxia [PDF]

Seminars in Pediatric Neurology, 2018
The human cerebral vasculature originates in the fourth week of gestation and continues to expand and diversify well into the first few years of postnatal life. A key feature of this growth is smooth muscle differentiation, whereby smooth muscle cells within cerebral arteries transform from migratory to proliferative to synthetic and finally to ...
openaire   +2 more sources