Results 51 to 60 of about 2,703 (208)

Synergies of Extracellular Vesicles and Microchimerism in Promoting Immunotolerance During Pregnancy

Frontiers in Immunology, 2022
The concept of biological identity has been traditionally a central issue in immunology. The assumption that entities foreign to a specific organism should be rejected by its immune system, while self-entities do not trigger an immune response is ...
José M. Murrieta-Coxca, Paulina Fuentes-Zacarias, Stephanie Ospina-Prieto, Udo R. Markert, Diana M. Morales-Prieto   +4 more
doaj   +1 more source

Influence of Fetomaternal Microchimerism on Maternal NK Cell Reactivity against the Child’s Leukemic Blasts

Biomedicines, 2022
Persistence of fetal cells in the circulation of the mother (fetal microchimerism, FM) is associated with increased survival and reduced relapse of children with leukemia receiving a haploidentical hematopoietic stem cell transplantation (hHSCT).
Lena-Marie Martin, Anne Kruchen, Boris Fehse, Ingo Müller   +3 more
doaj   +1 more source

TP53 mutation p.R337H in gastric cancer tissues of a 12-year-old male child - evidence for chimerism involving a common mutant founder haplotype: case report [PDF]

, 2011
Background: Gastric adenocarcinoma is rare in children and adolescents, with about 17 cases under age 21 in the world’s literature. We report a case of invasive well-differentiated metastatic gastric cancer in a Brazilian 12-year-old boy without ...
Edaise M da Silva, Maria Isabel W Achatz, Ghyslaine Martel-Planche, André L Montagnini, Magali Olivier, Patricia A Prolla, Pierre Hainaut, Fernando A Soares   +7 more
core   +1 more source

Fetal microchimerisms in the mother: Immunologic implications [PDF]

Liver Transplantation, 2000
The previously held concept that the fetus is completely separated from the mother, especially by trophoblasts that line the outer layer of the placenta, has recently been questioned. It has recently been shown that fetal cells are detectable not only in the peripheral blood, but also in maternal skin and liver.
A, Tanaka, K, Lindor, A, Ansari, M E, Gershwin   +3 more
openaire   +2 more sources

Understanding the association of stem cells in fetal development and carcinogenesis during pregnancy

Advances in Cancer Biology - Metastasis, 2022
Cancer during pregnancy is a rare event in the realm of obstetric statistics. Stem cells are known for their capability to renew their demographic to a variety of cell lineages.
Kasturi Banerjee, Agnibha Chattopadhyay, Satarupa Banerjee   +2 more
doaj   +1 more source

Acute Atherosis Lesions at the Fetal-Maternal Border: Current Knowledge and Implications for Maternal Cardiovascular Health

Frontiers in Immunology, 2021
Decidua basalis, the endometrium of pregnancy, is an important interface between maternal and fetal tissues, made up of both maternal and fetal cells. Acute atherosis is a uteroplacental spiral artery lesion. These patchy arterial wall lesions containing
Daniel Pitz Jacobsen, Heidi Elisabeth Fjeldstad, Heidi Elisabeth Fjeldstad, Guro Mørk Johnsen, Ingrid Knutsdotter Fosheim, Ingrid Knutsdotter Fosheim, Kjartan Moe, Kjartan Moe, Kjartan Moe, Patji Alnæs-Katjavivi, Ralf Dechend, Ralf Dechend, Meryam Sugulle, Meryam Sugulle, Anne Cathrine Staff, Anne Cathrine Staff   +15 more
doaj   +1 more source

Increased maternal microchimerism after open fetal surgery [PDF]

Chimerism, 2012
Maternal-fetal cellular trafficking (MFCT) during pregnancy leads to the presence of maternal cells in the fetus and of fetal cells in the mother. Since this process may be altered in cases of pregnancy complications, we asked whether open fetal surgery leads to changes in microchimerism levels.
Saadai, Payam, MacKenzie, Tippi C
openaire   +4 more sources

Savior Siblings Might Rescue Fetal Lethality But Not Adult Lymphoma in Irf2bp2-Null Mice

Frontiers in Immunology, 2022
Interferon regulatory factor 2 binding protein 2 (Irf2bp2), a co-repressor of Irf2, is required for fetal hepatic erythropoiesis through the expansion of erythromyeloid progenitors. Mice with germline ablation of the entire Irf2bp2 transcript produced no
Ragnar O. Vilmundarson, Ragnar O. Vilmundarson, Ragnar O. Vilmundarson, Niloufar Heydarikhorneh, Niloufar Heydarikhorneh, Niloufar Heydarikhorneh, An Duong, An Duong, An Duong, Tiffany Ho, Tiffany Ho, Tiffany Ho, Kianoosh Keyhanian, Kianoosh Keyhanian, Kianoosh Keyhanian, Kianoosh Keyhanian, Fariborz Soheili, Fariborz Soheili, Fariborz Soheili, Hsiao-Huei Chen, Hsiao-Huei Chen, Hsiao-Huei Chen, Hsiao-Huei Chen, Hsiao-Huei Chen, Alexandre F. R. Stewart, Alexandre F. R. Stewart, Alexandre F. R. Stewart   +26 more
doaj   +1 more source

Amniotic Epithelial Cells: A New Tool to Combat Aging and Age-Related Diseases? [PDF]

, 2016
The number of elderly people is growing at an unprecedented rate and this increase of the aging population is expected to have a direct impact on the incidence of age-related diseases and healthcare-associated costs. Thus, it is imperative that new tools
Barbara Barboni, Clara Di Germanio, Clara Di Germanio, Michel Bernier, Rafael de Cabo   +4 more
core   +2 more sources

The Use of Fluorescence In Situ Hybridization (FISH) on Paraffin-Embedded Tissue Sections for the Study of Microchimerism

BioTechniques, 2000
We describe here a simple and versatile method of fluorescence in situ hybridization (FISH) on paraffin-embedded tissue sections with specific application in the study of microchimerism, that is, the presence of intact foreign cells within an individual.
Kirby L. Johnson, Dong-Kai Zhen, Diana W. Bianchi   +2 more
doaj   +1 more source