Results 91 to 100 of about 11,138 (199)
FGF10 Is Required for Circumvallate Papilla Morphogenesis by Maintaining Lgr5 Activity
Frontiers in Physiology, 2018 Taste buds develop in different regions of the mammal oral cavity. Adult stem cells in various organs including the tongue papillae are marked by leucine-rich repeat-containing G protein-coupled receptor 5 (Lgr5) and its homolog, Lgr6.
Sushan Zhang +4 more
doaj +1 more source
Spatially Organized Human Ovarian Spheroids Instruct Endometrial Morphogenesis
Advanced Science, Volume 13, Issue 55, 5 October 2026.A spatially organized human follicle‐like spheroid (SPHEGaT) composed of granulosa cells (GCs) and stromal‐derived theca‐like cells (TLCs) establishes sustained steroidogenesis in vitro. When co‐cultured with human endometrial organoids (EMOs), estradiol (E2) and progesterone (P4) exchange induces secretory/progesterone‐responsive differentiation ...
Maria João Sousa +5 more
wiley +1 more source
Gata3 directly regulates early inner ear expression of Fgf10
, 2013 The analysis of Fgf10 mouse mutants has demonstrated a critical role for this ligand in neurosensory development of the vertebrate inner ear, and we have been looking to define the direct upstream regulators of Fgf10 in this sensory organ, as part of ...
Stephanie Cadot (16065467) +11 more
core +1 more source
Fibroblast Growth Factor 10 in Pancreas Development and Pancreatic Cancer
Frontiers in Genetics, 2018 The tenacious prevalence of human pancreatic diseases such as diabetes mellitus and adenocarcinoma has prompted huge research interest in better understanding of pancreatic organogenesis.
Rodrick Ndlovu +7 more
doaj +1 more source
Advanced Science, Volume 13, Issue 55, 5 October 2026.This study established a high‐quality organoid biobank derived from 68 tumor sites across 50 Chinese patients, elucidated the drug sensitivity‐based molecular subtyping in breast cancer, and revealed a novel mechanism of drug resistance mediated by the FAK‐ACSL1 pathway.
Hao Xu +10 more
wiley +1 more source
Video2_Negative Transpulmonary Pressure Disrupts Airway Morphogenesis by Suppressing Fgf10.AVI
, 2021 Mechanical forces are increasingly recognized as important determinants of cell and tissue phenotype and also appear to play a critical role in organ development.
Amira L. Pavlovich (11777654) +6 more
core +1 more source
A dualistic approach to heart repair through FGF10
Cardiovascular Research, 2022 Tim Koopmans, Eva van Rooij
openaire +5 more sources
Video1_Negative Transpulmonary Pressure Disrupts Airway Morphogenesis by Suppressing Fgf10.AVI
, 2021 Mechanical forces are increasingly recognized as important determinants of cell and tissue phenotype and also appear to play a critical role in organ development.
Amira L. Pavlovich (11777654) +6 more
core +1 more source
Fgf10 is required for specification of non-sensory regions of the cochlear epithelium [PDF]
, 2014 pre-printThe vertebrate inner ear is a morphologically complex sensory organ comprised of two compartments, the dorsal vestibular apparatus and the ventral cochlear duct, required for motion and sound detection, respectively.
Mansour, Suzanne L. +1 more
core
ISL1 directly regulates FGF10 transcription during human cardiac outflow formation.
PLoS ONE, 2012 The LIM homeodomain gene Islet-1 (ISL1) encodes a transcription factor that has been associated with the multipotency of human cardiac progenitors, and in mice enables the correct deployment of second heart field (SHF) cells to become the myocardium of ...
Christelle Golzio +9 more
doaj +1 more source