Organ-Specific Branching Morphogenesis [PDF]
Frontiers in Cell and Developmental Biology, 2021 A common developmental process, called branching morphogenesis, generates the epithelial trees in a variety of organs, including the lungs, kidneys, and glands.
Dagmar Iber, Lisa Conrad, Christine Lang
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Protocol for inducing branching morphogenesis in human cholangiocyte and cholangiocarcinoma organoids [PDF]
STAR Protocols, 2023 Summary: Bile ducts are essential for bile transport and consist of complex branching tubular networks. Human patient-derived cholangiocyte develops a cystic rather than branching duct morphology.
Kimberley Ober +7 more
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Bim Expression Modulates Branching Morphogenesis of the Epithelium and Endothelium [PDF]
Biomolecules, 2022 Branching morphogenesis is a key developmental process during organogenesis, such that its disruption frequently leads to long-term consequences.
Christine M. Sorenson +6 more
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ΔNp63 regulates Sfrp1 expression to direct salivary gland branching morphogenesis. [PDF]
PLoS ONEBranching morphogenesis is a complex process shared by many organs including the lungs, kidney, prostate, as well as several exocrine organs including the salivary, mammary and lacrimal glands. This critical developmental program ensures the expansion of
Theresa Wrynn +5 more
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Intraluminal chloride regulates lung branching morphogenesis: involvement of PIEZO1/PIEZO2 [PDF]
Respiratory Research, 2023 Background Clinical and experimental evidence shows lung fluid volume as a modulator of fetal lung growth with important value in treating fetal lung hypoplasia.
Ana N. Gonçalves +3 more
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A Mammary Organoid Model to Study Branching Morphogenesis [PDF]
Frontiers in Physiology, 2022 Branching morphogenesis is the process that gives rise to branched structures in several organs, such as the lung, the kidney, and the mammary gland. Although morphologically well described, the exact mechanisms driving branch elongation and bifurcation ...
Marika Caruso +5 more
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ECM Signaling Regulates Collective Cellular Dynamics to Control Pancreas Branching Morphogenesis
Cell Reports, 2016 During pancreas development, epithelial buds undergo branching morphogenesis to form an exocrine and endocrine gland. Proper morphogenesis is necessary for correct lineage allocation of pancreatic progenitors; however, the cellular events underlying ...
Maike Sander +2 more
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Extracellular Matrix Viscoelasticity Regulates Mammary Branching Morphogenesis [PDF]
Advanced ScienceStructural and mechanical cues from the extracellular matrix (ECM) regulate tissue morphogenesis. Tissue development has conventionally been studied with ex vivo systems where the mechanical properties of the extracellular environment are either poorly ...
Daniella I. Walter +3 more
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Regulatory Mechanisms of Branching Morphogenesis in Mouse Submandibular Gland Rudiments
Japanese Dental Science Review, 2018 Summary: Branching morphogenesis is an important developmental process for many organs, including the salivary glands. Whereas epithelial–mesenchymal interactions, which are cell-to-cell communications, are known to drive branching morphogenesis, the ...
Masanori Kashimata, Toru Hayashi
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Biology, 2021 Branching morphogenesis and seamless tube formation in Drosophila melanogaster are essential for the development of vascular and tracheal systems, and instructive in studying complex branched structures such as human organs. Zipper is a myosin II’s actin-
Jong-Hyeon Shin, Chan-Woo Jeong
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