Lung branching morphogenesis is accompanied by temporal metabolic changes towards a glycolytic preference [PDF]
Cell & Bioscience, 2021 Background Lung branching morphogenesis is characterized by epithelial-mesenchymal interactions that ultimately define the airway conducting system.
Hugo Fernandes-Silva +6 more
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Mathematical Approaches of Branching Morphogenesis [PDF]
Frontiers in Genetics, 2018 Many organs require a high surface to volume ratio to properly function. Lungs and kidneys, for example, achieve this by creating highly branched tubular structures during a developmental process called branching morphogenesis.
Christine Lang +2 more
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Role of Claudins in Renal Branching Morphogenesis [PDF]
Physiological Reports, 2020 Claudins are a family of tight junction proteins that are expressed during mouse kidney development. They regulate paracellular transport of solutes along the nephron and contribute to the final composition of the urinary filtrate.
Jasmine El Andalousi +4 more
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From Clones to Buds and Branches: The Use of Lung Organoids to Model Branching Morphogenesis Ex Vivo [PDF]
Frontiers in Cell and Developmental Biology, 2021 Three-dimensional (3D) organoid culture systems have rapidly emerged as powerful tools to study organ development and disease. The lung is a complex and highly specialized organ that comprises more than 40 cell types that offer several region-specific ...
Ana Ivonne Vazquez-Armendariz +5 more
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Ret and Etv4 Promote Directed Movements of Progenitor Cells During Renal Branching Morphogenesis
PLoS Biology, 2016 Branching morphogenesis of the epithelial ureteric bud forms the renal collecting duct system and is critical for normal nephron number, while low nephron number is implicated in hypertension and renal disease.
Cristina Cebrián +2 more
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Editorial: Branching Morphogenesis During Embryonic Lung Development [PDF]
Frontiers in Cell and Developmental Biology, 2021 Elie El Agha +2 more
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Frontiers in Cell and Developmental Biology, 2021 Airway branching morphogenesis depends on the intricate orchestration of numerous biological and physical factors connected across different spatial scales.
Matthew R. Jones +4 more
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Microtubule dependent changes in cell polarity are required for mammary epithelial cell migration and branching morphogenesis [PDF]
Biology OpenAndrew K. Fraser +4 more
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Melatonin inhibits embryonic salivary gland branching morphogenesis by regulating both epithelial cell adhesion and morphology. [PDF]
PLoS ONE, 2015 Many organs, including salivary glands, lung, and kidney, are formed by epithelial branching during embryonic development. Branching morphogenesis occurs via either local outgrowths or the formation of clefts that subdivide epithelia into buds.
Aya Obana-Koshino +9 more
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Expression and functional role of sprouty-2 in breast morphogenesis. [PDF]
PLoS ONE, 2013 Branching morphogenesis is a mechanism used by many species for organogenesis and tissue maintenance. Receptor tyrosine kinases (RTKs), including epidermal growth factor receptor (EGFR) and the sprouty protein family are believed to be critical ...
Valgardur Sigurdsson +8 more
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