Results 21 to 30 of about 38,022 (189)
Biomolecules, 2021 The molecular mechanisms underlying prostate development can provide clues for prostate cancer research. It has been demonstrated that MEK/ERK signaling downstream of androgen-targeted FGF10 signaling directly induces prostatic branching during ...
Wen-Yang Hu +5 more
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Spatiotemporal changes in microtubule dynamics during dendritic morphogenesis
Fly, 2022 Dendritic morphogenesis requires dynamic microtubules (MTs) to form a coordinated cytoskeletal network during development. Dynamic MTs are characterized by their number, polarity and speed of polymerization.
Chun Hu +4 more
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Actin depolymerizing factors cofilin1 and destrin are required for ureteric bud branching morphogenesis. [PDF]
PLoS Genetics, 2010 The actin depolymerizing factors (ADFs) play important roles in several cellular processes that require cytoskeletal rearrangements, such as cell migration, but little is known about the in vivo functions of ADFs in developmental events like branching ...
Satu Kuure +9 more
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The control of branching morphogenesis [PDF]
Open Biology, 2013 Many organs of higher organisms are heavily branched structures and arise by an apparently similar process of branching morphogenesis. Yet the regulatory components and local interactions that have been identified differ greatly in these organs. It is an
Dagmar Iber, Denis Menshykau
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Fetal calcium regulates branching morphogenesis in the developing human and mouse lung: involvement of voltage-gated calcium channels. [PDF]
PLoS ONE, 2013 Airway branching morphogenesis in utero is essential for optimal postnatal lung function. In the fetus, branching morphogenesis occurs during the pseudoglandular stage (weeks 9-17 of human gestation, embryonic days (E)11.5-16.5 in mouse) in a ...
Sarah C Brennan +7 more
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A positive feedback loop involving Gcm1 and Fzd5 directs chorionic branching morphogenesis in the placenta. [PDF]
PLoS Biology, 2013 Chorioallantoic branching morphogenesis is a key milestone during placental development, creating the large surface area for nutrient and gas exchange, and is therefore critical for the success of term pregnancy.
Jinhua Lu +17 more
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Turing mechanism underlying a branching model for lung morphogenesis. [PDF]
PLoS ONE, 2017 The mammalian lung develops through branching morphogenesis. Two primary forms of branching, which occur in order, in the lung have been identified: tip bifurcation and side branching.
Hui Xu, Mingzhu Sun, Xin Zhao
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A systematic screen for tube morphogenesis and branching genes in the Drosophila tracheal system.
PLoS Genetics, 2011 Many signaling proteins and transcription factors that induce and pattern organs have been identified, but relatively few of the downstream effectors that execute morphogenesis programs.
Amin S Ghabrial +2 more
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Directing Cholangiocyte Morphogenesis in Natural Biomaterial Scaffolds
Advanced Science, 2022 Patients with Alagille syndrome carry monogenic mutations in the Notch signaling pathway and face complications such as jaundice and cholestasis. Given the presence of intrahepatic ductopenia in these patients, Notch2 receptor signaling is implicated in ...
Quinton Smith +5 more
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Nature Communications, 2019 Many organs develop through branching morphogenesis, but whether the underlying mechanisms are shared is unknown. Here, the authors show that a ligand-receptor based Turing mechanisms, similar to that observed in lung development, likely underlies ...
Denis Menshykau +5 more
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