Results 151 to 160 of about 38,475 (260)
Journal of Cellular Physiology, Volume 241, Issue 8, August 2026.ABSTRACT Ageing is a major risk factor for degenerative diseases, including sarcopenia, which is characterized by a progressive loss of skeletal muscle mass and function, frailty, and is associated with increased mortality. Skeletal muscle regeneration relies on muscle stem cells and efficient communication with cellular microenvironment.
Juan Diego Hernández‐Camacho +1 more
wiley +1 more source
Molecular Reproduction and Development, Volume 93, Issue 8, August 2026.Follicle size modulates bovine oocyte cytoplasmic maturation during IVM. Oocytes from larger follicles exhibit reduced lipid accumulation, fewer transzonal projections, distinct cumulus cell metabolic signaling, and greater embryo cryosurvival, indicating improved cytoplasmic maturation and lipid regulation despite similar developmental rates ...
Briza Castro +2 more
wiley +1 more source
Application of Systems Genetics to Investigate Molecular Pathology of Early‐Onset Colorectal Cancer
Chemical Biology &Drug Design, Volume 108, Issue 2, August 2026.Early‐onset colorectal cancer (EOCRC) presents a complex molecular landscape that requires integrated multi‐omics approaches. This article reviews current applications of systems genetics in EOCRC research and provides a step‐by‐step protocol for network‐based analyses featuring PIK3CA to demonstrate practical application for researchers of all levels.
Minjae J. Kim +3 more
wiley +1 more source
Lysine l‐Lactylation: Bridging Metabolism, Chromatin and Disease
Cell Proliferation, Volume 59, Issue 8, August 2026.Enzymatic regulation of KL‐la. The enzymatic regulation of KL‐la involves two distinct pathways for L‐lactate accumulation: intracellular production through glycolysis‐derived pyruvate conversion by lactate dehydrogenase (LDH) or direct cellular uptake via monocarboxylate transporters (MCTs). These L‐lactate pools fuel two distinct lactylation pathways—
Anoosha Malik +10 more
wiley +1 more source
Journal of Cellular and Molecular Medicine, Volume 30, Issue 16, August 2026.ABSTRACT Myotonic dystrophy type 1 (DM1) is a progressive muscular disorder caused by the expansion of CTG repeats in the 3′ UTR of the DMPK gene. Although the pathogenic mechanisms remain unclear, recent evidence suggests that activation of innate immune responses may contribute to disease progression. In this study, we examined the ultrastructure and
Renata Del Carratore +8 more
wiley +1 more source
Molecular Vision, 2019 Purpose: To determine whether the mouse corneal endothelium enters endothelial to mesenchymal transition (EndoMT) following surgical injury in vivo. Methods: The corneal endothelium in anesthetized mice was surgically injured in vivo under direct ...
JeongGoo Lee, Eric Jung, Martin Heur
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Journal of Cosmetic Dermatology, Volume 25, Issue 8, August 2026.ABSTRACT Background GLP‐1 receptor agonists (GLP‐1 RAs) can induce rapid weight reduction, often associated with facial volume loss. However, optimal regenerative strategies remain unclear. Aims To compare the mechanotransduction profiles of the major injectable collagen biostimulator classes in GLP‐1 RA–induced facial aging.
Chang‐Hwan Cho +2 more
wiley +1 more source
Fibroblast Growth Factor 2-Immobilized Biointerfaces Drive Exogenous Transforming Growth Factor β1-Independent Chondrogenesis of Human Mesenchymal Stem Cell and Ectopic Cartilage Tissue Formation. [PDF]
Biomater ResJeong JH +10 more
europepmc +1 more source
Digit regeneration in mice is stimulated by sequential treatment with FGF2 and BMP2. [PDF]
Nat CommunYu L +14 more
europepmc +1 more source