Results 131 to 140 of about 35,769 (259)
Computational and Systems Oncology, Volume 6, Issue 1, December 2026.ABSTRACT Resistance to chemotherapy, which is demonstrated in almost every patient with advanced‐stage lung cancer (ALC), underscores an urgent need to unravel the underlying molecular mechanisms and identify novel strategies to overcome drug resistance. In the present study, an attempt was made to identify epigenetic targets and modulators that can be
Okibur Rahman +2 more
wiley +1 more source
Effects of FGF2 and antagonist of FGF2 receptor-1 on the excitability of dopamine neurons in rats
Neuroscience Applied, 2022 E. Dremencov +5 more
openaire +1 more source
Nucleolin binds to FGF1 and FGF2.
, 2014 A) Proteins from cleared cell lysates (BJ or NIH3T3 cells) were pulled down by SBP-FGF1, Biot-FGF2, His-FGF1, GST-FGF1, GST-FGF2, GST protein, or no protein (–), and respective resins (Streptavidin-coated Dynabeads, Ni-NTA Superflow or Glutathione ...
Torunn Sletten (530507) +9 more
core +1 more source
Aging Cell, Volume 25, Issue 7, July 2026.This review systematically elucidates the multifactorial anti‐aging mechanisms of extracellular vesicles (EVs). By bridging fundamental biology with advanced bioengineering, scalable manufacturing, and clinical translation, it establishes a comprehensive framework for developing next‐generation EVs‐based precision nanotherapeutics to combat systemic ...
Xian Huang +6 more
wiley +1 more source
Scientific ReportsFibroblast growth factor 2 (FGF2) is a crucial factor in odontoblast differentiation and dentin matrix deposition, which facilitates pulpodentin repair and regeneration.
Zijie Wang +6 more
doaj +1 more source
SIK2: A Novel Negative Feedback Regulator of FGF2 Signaling
Advanced BiologyAbstract A wide range of cells respond to fibroblast growth factor 2 (FGF2) by proliferation via activation of the Ras/ERK1/2 pathway. In this study, the potential involvement of salt inducible kinase SIK2) in this cascade within retinal Müller glia is explored.
Gamze Kuser‐Abali +5 more
openaire +3 more sources
α-Tocopheryl succinate inhibits angiogenesis by disrupting paracrine FGF2 signalling
, 2007 Malignant mesothelioma (MM) cells enhanced proliferation of endothelial cells (ECs) as well as their angiogenesis in vitro by secretion of fibroblast growth factor-2 (FGF2). This effect was suppressed by pre-treating MM cells with α-tocopheryl succinate (
Stapelberg, Michael +11 more
core +1 more source
Genomic Analysis of Inbreeding Depression on Productive Traits in Rubia Galega Beef Cattle Breed
Journal of Animal Breeding and Genetics, Volume 143, Issue 4, Page 508-523, July 2026.ABSTRACT In autochthonous livestock breeds with small populations, such as the Rubia Galega from Galicia (Spain), mating between relatives is common and can lead to inbreeding depression. Genomic inbreeding coefficients were estimated for 4984 animals using ~63,000 SNPs to assess inbreeding depression in four key traits: age at first calving (AFC) with
N. Mejuto‐Vázquez +6 more
wiley +1 more source
FGF2 treatment increases the absolute number of tectal cells.
, 2013 Intra-ventricular injections of FGF2 on ED4 decrease the number of cells above a unit area of ventricular surface by 14% compared to controls (A). Taking into account our previous observation that FGF2 increases tectal ventricular surface area by 181% [3]
Luke D. McGowan (483282) +2 more
core +1 more source
Advanced Healthcare Materials, Volume 15, Issue 21, 5 June 2026.Neural cell–derived small extracellular vesicles (sEVs) are emerging as pivotal mediators in neurodegenerative diseases, exerting both pathogenic and therapeutic functions. This review synthesizes current evidence on how sEVs from distinct neural cell types regulate neurodegeneration, neuroprotection, biomarker discovery, and targeted drug delivery ...
Muhammad Waqas Salim +4 more
wiley +1 more source