Results 111 to 120 of about 35,769 (259)
FGF2-dependent cell proliferation in vitro.
, 2013 A) Low-passage glioma cell lines were cultured in a growth factor cocktail consisting of SHH, PDGFA and FGF2 (+FGF2), or only SHH and PDGFA (−FGF2). The relative cell numbers after one passage of culture for 7 to 10 days are shown under the 2 conditions.
David Gisselsson Nord (405193) +7 more
core +1 more source
Cancer Science, EarlyView.Spatial transcriptomics and bulk RNA‐seq data analysis revealed the molecular characteristics of invasive lobular carcinoma (ILC). ILC was classified into three clusters: proliferative, immunoreactive, and stromal‐rich, with different prognoses. ABSTRACT Invasive lobular carcinoma (ILC) is a special type of breast cancer.
Momoko Tokura +9 more
wiley +1 more source
FGF2-dependent maintenance of PDGFRA expression.
, 2013 A) Percentages of PDGFRA-positive cells in the indicated glioma cell lines (L1–L9) following a culture for 7 to 10 days with (+) or without (−) FGF2 support.
David Gisselsson Nord (405193) +7 more
core +1 more source
Cell Proliferation, EarlyView.This review outlines kidney organoid differentiation strategies, key developmental mechanisms, and engineering and multi‐omics approaches driving their progress toward regenerative medicine. ABSTRACT Chronic kidney disease (CKD) has emerged as a critical public health challenge worldwide, and organ donor shortages underscore the urgent need for ...
Bohong Guo +9 more
wiley +1 more source
Cell Proliferation, EarlyView.Polyamine metabolism is innervation responsive and involved in denervation‐induced muscle atrophy. Inhibition of polyamine metabolism attenuates muscle atrophy by restraining proteolysis and preserving MuSCs homeostasis. Denervation‐induced activation of FAP‐derived FGF7 drives premature MuSCs activation, while DFMO suppresses this paracrine cue to ...
Mingming Zhang +9 more
wiley +1 more source
Cell Proliferation, EarlyView.During development, the oxygen‐sensitive transcription factor Zeb2 restrains astrocyte proliferation and maturation to ensure balanced retinal angiogenesis. In disease, it promotes the neurotoxic A1 astrocyte phenotype and inflammation, thereby promoting reparative revascularization over pathological neovascularization.
Jing Liu +5 more
wiley +1 more source
Activation of FGF2 IRES-dependent expression by hypoxia in vitro.
, 2013 A. Representative Western blot analysis of FGF-2 isoforms and HIF-1α in 911 retinoblasts grown in normoxic (N) and hypoxic (H) conditions for the indicated time periods. B.
Céline Toutain (88345) +6 more
core +1 more source
Proteolytic remodelling of the extracellular matrix by pericytes
The FEBS Journal, EarlyView.Pericytes are specialised perivascular cells intimately connected with endothelial cells and essential for the maintenance of vascular beds. They contribute to the formation and remodelling of the extracellular matrix by actively secreting proteases and protease inhibitors.
Tina Burkhard +4 more
wiley +1 more source
Activation of sperm FGFRs in response to FGF2.
, 2015 Localization of sperm pFGFRs by immunocytochemistry. Sperm were incubated for 4 h and exposed to FGF2 (0, 1, 10 and 100 ng/ml) for the last 15 min. In some aliquots, sperm were incubated for 15 min with BGJ398 (0.1 μM) before the addition of FGF2.
Mónica H. Vazquez-Levin (738258) +7 more
core +1 more source
Journal of Periodontal Research, EarlyView.The scoping review summarizes the current preclinical and clinical evidence for the use of “cell‐free” therapies in craniofacial (periodontal, bone and soft‐tissue) regeneration. It also aims to highlight key challenges and strategies towards the clinical translation of these therapies.
Siddharth Shanbhag +6 more
wiley +1 more source