Results 121 to 130 of about 35,769 (259)

Structural and biochemical investigation into stable FGF2 mutants with novel mutation sites and hydrophobic replacements for surface-exposed cysteines.

PLoS ONE
Fibroblast growth factor 2 (FGF2) is an attractive biomaterial for pharmaceuticals and functional cosmetics. To improve the thermo-stability of FGF2, we designed two mutants harboring four-point mutations: FGF2-M1 (D28E/C78L/C96I/S137P) and FGF2-M2 (D28E/
Young Jun An, Ye-Eun Jung, Kyeong Won Lee, Prashant Kaushal, In Young Ko, Seung Min Shin, Sangho Ji, Wookyung Yu, Cheolju Lee, Won-Kyu Lee, Kiweon Cha, Jung-Hyun Lee, Sun-Shin Cha, Hyung-Soon Yim   +13 more
doaj   +1 more source

Montage of a false color photothermal image of FGF2-nanoparticles on two fibroblast cells and of an electron micrograph showing the clustering of FGF2-nanoparticles (black dots) with a superimposed track of an FGF2 (red line).

, 2012
Montage of a false color photothermal image of FGF2-nanoparticles on two fibroblast cells and of an electron micrograph showing the clustering of FGF2-nanoparticles (black dots) with a superimposed track of an FGF2 (red line).
Richard Robinson (3807)
core   +1 more source

Optimization of photobiomodulation therapy for spinal cord injury: A review

Photochemistry and Photobiology, EarlyView.
Photobiomodulation (PBM) therapy in the red and near‐infrared range can significantly modulate the secondary injury response and promote the reparative and regenerative potential of neural tissue after spinal cord injury (SCI). At present, due to the nature of delivery methods, the most effective dose and irradiance at the injury site to optimize ...
Isabella K. M. Drew, Alan R. Harvey, Vincent P. Wallace, Stuart I. Hodgetts   +3 more
wiley   +1 more source

Hyaluronic acid: A novel approach in regenerative/reconstructive periodontal therapy?

Periodontology 2000, EarlyView.
Abstract Background Although hyaluronic acid (HA) has long been used for many medical applications, only in recent years has it gained greater popularity in the field of periodontics because of its biological effects during wound healing. Even today, most clinicians are not aware that more than one type of HA exists and that the extent of its ...
Andrea Pilloni, Yoshinori Shirakata, Lorenzo Marini, Darko Božić, Richard J. Miron, Roberto Rotundo, Andreas Stavropoulos, Anton Sculean   +7 more
wiley   +1 more source

Engineered FGF1 and FGF2 compositions and methods of use thereof

, 2022
Engineered FGF1 and FGF2 polypeptides, polynucleotides encoding these polypeptides and DNA constructs, vectors and compositions including these engineered polypeptides are provided herein.
Gundampati, Ravi Kumar, Kolenc, Olivia, Lam, Ngoc Thien, Balachandran, Kartik, Jones, Jake, Quinn, Kyle, Wang, Tengjiao, Niyonshuti, Isabelle Ishimwe, Kumar, Thallapuranam Krishnaswamy Suresh, Agarwal, Shilpi, Jayanthi, Srinivas, Chen, Jingyi   +11 more
core  

Ideal soft tissue graft in periodontal and peri‐implant applications: A scoping review

Periodontology 2000, EarlyView.
Abstract Soft tissue grafts (STG) are used in a wide range of clinical situations including volume augmentation, keratinized tissue increase, and recession coverage around teeth and implants. Each STG, produced from different sources and processed with various techniques, possesses unique material properties and interaction with the host tissues, which
Madeline Yon, Elena Calciolari, Nikos Mardas, Anton Sculean, Nikolaos Donos   +4 more
wiley   +1 more source

Increased FGF2 expression promotes immune cell infiltration and correlates with an unfavorable prognosis in thyroid cancer

Heliyon
To delve into the expression and functions of FGF2 in patient with thyroid cancer (THCA), we conducted a systematic analysis of the association of FGF2 with immune cell infiltration, and prognosis in THCA patients.
Han Chen, Xiaoyun Du
doaj   +1 more source

FGF2 regulates sub-cellular localisation of SMAD1.

, 2013
A. Primary cultures of E14 dorsal neural precursor cells were treated with FGF2, BMP4 or FGF2+U0126 for 6 hours or 24 hours and labelled for C-term-pSMAD1. Representative fields from 6 hours treatment is shown. B. Cells showing an exclusive nuclear or an
Nicholas D. Allen (94754), Bilada Bilican (94751), Alastair Compston (94753), Siddharthan Chandran (94755), Christelle Fiore-Heriche (94752)   +4 more
core   +1 more source

Treating age‐related loss of muscle mass and function: Where should we be focusing?

The Journal of Physiology, EarlyView.
Abstract figure legend Perturbations contributing to the age‐related loss of muscle mass and strength. A, in the spinal cord, self‐reinforcing cycles of oxidative stress, mitochondrial dysfunction and inflammation mediated by cells, including microglia, contribute to motor neuron degeneration.
Daniel J. Ham, Christopher S. Fry, Avnika Ashok Ruparelia, Shyuan T. Ngo, Séverine Lamon   +4 more
wiley   +1 more source

Endogenous FGF2 and HIF-1α expression in ischemic skin extracts.

, 2013
A. Representative Western blot analyses of FGF2 and HIF-1α at the indicated post-operative time. The molecular weights of FGF2 mouse isoforms are indicated. B. Levels of endogenous FGF2 mRNA determined by RT-qPCR analysis.
Céline Toutain (88345), Elodie Riant (88344), Françoise Pujol (88346), Jean-François Arnal (83695), Françoise Lenfant (88347), Caroline Conte (88343), Anne-Catherine Prats (4523)   +6 more
core   +1 more source