Results 141 to 150 of about 35,769 (259)

FGF2 maintain iPSC and increase differentiation potential of hESC.

open access: yes, 2013
(A) iPSC lines were derived and assessed for pluripotency markers (B) iPSCs grown for two weeks on matrigel exhibit a similar FACS stem cell profile when fed with medium+FGF2 beads every third day compared to conventional medium+soluble FGF2 daily ...
Ravi S. Kane (378375)   +11 more
core   +1 more source

Recapitulating Endochondral Ossification for Bone Repair: From Development to Engineering Strategy

open access: yesAdvanced Healthcare Materials, Volume 15, Issue 23, 19 June 2026.
This review summarizes the developmental basis of endochondral ossification (ECO) and its applications in bone tissue engineering (BTE). It first outlines the key biological processes and signaling pathways underlying ECO, then discusses biomaterial‐based engineering strategies derived from these principles, and finally highlights future directions for
Yiqi Su   +8 more
wiley   +1 more source

Uronyl 2-O sulfotransferase potentiates Fgf2-induced cell migration

open access: yes, 2015
Fibroblast growth factor 2 (Fgf2) is involved in several biological functions. Fgf2 requires glycosaminoglycans, like chondroitin and dermatan sulfates (hereafter denoted CS/DS) as co-receptors.
Spillmann, Dorothe,   +2 more
core   +1 more source

Blood‐based proteomic signature of amyloidosis: identification of novel regulators of amyloid load

open access: yesAlzheimer's &Dementia, Volume 22, Issue 6, June 2026.
Abstract INTRODUCTION Cerebral amyloidosis is a defining feature of Alzheimer's disease (AD), yet the molecular heterogeneity among amyloidbeta‐positive (Aβ+) individuals remains poorly defined. We aimed to map the proteomic correlates of cerebral amyloidosis and link them to clinical variability within Aβ+ individuals.
Yike Chen   +18 more
wiley   +1 more source

Functional effect of FGF2- and FGF8-expanded ventral mesencephalic precursor cells in a rat model of Parkinson's disease

open access: yes, 2008
Ventral mesencephalic (VM) precursor cells are of interest in the search for transplantable dopaminergic neurons for cell therapy in Parkinson's disease (PD). In the present study we investigated the survival and functional capacity of in vitro expanded,
Pedersen, Emil Arnspang   +5 more
core   +1 more source

Integrative Single‐Cell RNA Sequencing and Spatial Transcriptomics Uncover Distinct Fibroblast–Macrophage Crosstalk in Human Hip Synovium Between Patients With Femoroacetabular Impingement and Osteoarthritis

open access: yesArthritis &Rheumatology, Volume 78, Issue 6, Page 1219-1230, June 2026.
Objective Femoroacetabular impingement (FAI) and synovitis have been recognized as essential factors for developing osteoarthritis (OA) in the hip joints. However, little is known about altered synovial cellular compositions, their associated transcriptomic profiles, and cell–cell interactions in FAI and hip OA.
Gulzada Kulzhanova   +9 more
wiley   +1 more source

Chemical shift perturbation upon variation in FGF2 concentrations.

open access: yes, 2014
A. HSQC spectra of heparin column purified FGF2 of 1.5 mM (purple), 1.1 mM (Blue), 0.55 mM (green), 0.275 mM (orange) and 0.137 mM (red). B. HSQC spectra of ion-exchange column purified FGF2 of 1 mM (black) and 0.125 mM (red).
Giorgio Colombo (65952)   +8 more
core   +1 more source

Lactate metabolism and lactylation in female reproductive diseases: From metabolic rewiring to biomarkers and translational therapeutics

open access: yesClinical and Translational Medicine, Volume 16, Issue 6, June 2026.
1. Lactate‐derived histone lactylation links glycolytic reprogramming to epigenetic regulation in female reproductive diseases. 2. In endometriosis, lactylation may promote inflammatory remodelling, immune dysregulation and ferroptosis resistance. 3. In PCOS, lactylation connects metabolic disturbance to granulosa‐cell dysfunction and hyperandrogenism.
Jiajun Qiao   +5 more
wiley   +1 more source

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