Results 141 to 150 of about 35,769 (259)
FGF2 maintain iPSC and increase differentiation potential of hESC.
(A) iPSC lines were derived and assessed for pluripotency markers (B) iPSCs grown for two weeks on matrigel exhibit a similar FACS stem cell profile when fed with medium+FGF2 beads every third day compared to conventional medium+soluble FGF2 daily ...
Ravi S. Kane (378375) +11 more
core +1 more source
Recapitulating Endochondral Ossification for Bone Repair: From Development to Engineering Strategy
This review summarizes the developmental basis of endochondral ossification (ECO) and its applications in bone tissue engineering (BTE). It first outlines the key biological processes and signaling pathways underlying ECO, then discusses biomaterial‐based engineering strategies derived from these principles, and finally highlights future directions for
Yiqi Su +8 more
wiley +1 more source
Uronyl 2-O sulfotransferase potentiates Fgf2-induced cell migration
Fibroblast growth factor 2 (Fgf2) is involved in several biological functions. Fgf2 requires glycosaminoglycans, like chondroitin and dermatan sulfates (hereafter denoted CS/DS) as co-receptors.
Spillmann, Dorothe, +2 more
core +1 more source
Blood‐based proteomic signature of amyloidosis: identification of novel regulators of amyloid load
Abstract INTRODUCTION Cerebral amyloidosis is a defining feature of Alzheimer's disease (AD), yet the molecular heterogeneity among amyloidbeta‐positive (Aβ+) individuals remains poorly defined. We aimed to map the proteomic correlates of cerebral amyloidosis and link them to clinical variability within Aβ+ individuals.
Yike Chen +18 more
wiley +1 more source
Ventral mesencephalic (VM) precursor cells are of interest in the search for transplantable dopaminergic neurons for cell therapy in Parkinson's disease (PD). In the present study we investigated the survival and functional capacity of in vitro expanded,
Pedersen, Emil Arnspang +5 more
core +1 more source
Objective Femoroacetabular impingement (FAI) and synovitis have been recognized as essential factors for developing osteoarthritis (OA) in the hip joints. However, little is known about altered synovial cellular compositions, their associated transcriptomic profiles, and cell–cell interactions in FAI and hip OA.
Gulzada Kulzhanova +9 more
wiley +1 more source
Chemical shift perturbation upon variation in FGF2 concentrations.
A. HSQC spectra of heparin column purified FGF2 of 1.5 mM (purple), 1.1 mM (Blue), 0.55 mM (green), 0.275 mM (orange) and 0.137 mM (red). B. HSQC spectra of ion-exchange column purified FGF2 of 1 mM (black) and 0.125 mM (red).
Giorgio Colombo (65952) +8 more
core +1 more source
1. Lactate‐derived histone lactylation links glycolytic reprogramming to epigenetic regulation in female reproductive diseases. 2. In endometriosis, lactylation may promote inflammatory remodelling, immune dysregulation and ferroptosis resistance. 3. In PCOS, lactylation connects metabolic disturbance to granulosa‐cell dysfunction and hyperandrogenism.
Jiajun Qiao +5 more
wiley +1 more source

