Results 1 to 10 of about 19,683 (144)
Deletion of cardiac fibroblast growth factor-23 beneficially impacts myocardial energy metabolism in left ventricular hypertrophy [PDF]
npj Metabolic Health and DiseaseLeft ventricular hypertrophy (LVH) is associated with increased cardiac expression of fibroblast growth factor-23 (FGF23) in mice and men. To further elucidate the role of cardiac FGF23 in LVH, we specifically ablated Fgf23 in cardiomyocytes, and ...
Nejla Latic +13 more
doaj +2 more sources
Interactions of sclerostin with FGF23, soluble klotho and vitamin D in renal transplantation [PDF]
, 2017 Relationships of Sclerostin, a bone anti-anabolic protein, with biomarkers of mineral bone disorders in chronic kidney disease are still unsettled, in particular in kidney transplant (KTR).
Farcomeni, Alessio +7 more
core +10 more sources
Endocrine Connections, 2021 Intrauterine growth restriction (IUGR) reflects inadequate growth in-utero and is prevalent in low resource settings. This study aimed to assess the association of maternal delivery parathyroid hormone (PTH) – a regulator of bone turnover and calcium ...
Huma Qamar +5 more
doaj +1 more source
Interactions between FGF23 and vitamin D
Endocrine Connections, 2022 Fibroblast growth factor‐23 (FGF23) controls the homeostasis of both phosphate and vitamin D. Bone-derived FGF23 can suppress the transcription of 1α‐hydroxylase (1α(OH)ase) to reduce renal activation of vitamin D (1,25(OH)2D3).
Mohammed S Razzaque
doaj +1 more source
Plasma fibroblast growth factor 23 concentration is increased and predicts mortality in patients on the liver-transplant waiting list. [PDF]
PLoS ONE, 2013 High plasma fibroblast growth factor-23 (FGF23) concentration predicts the risk of death and poor outcomes in patients with chronic kidney disease or chronic heart failure.
Dominique Prié +9 more
doaj +1 more source
Bone Reports, 2023 While the positive association between automated intact fibroblast growth factor (FGF) 23 measurement kit (Determinar CL FGF23 [CL]) and the former assay (Kainos [KI]), and clinical utility of CL was well established, the clinical performance of ...
Hajime Kato +8 more
doaj +1 more source
Promotion effect of FGF23 on osteopenia in congenital scoliosis through FGFr3/TNAP/OPN pathway
Chinese Medical Journal, 2023 . Background:. Congenital scoliosis (CS) is a complex spinal malformation of unknown etiology with abnormal bone metabolism. Fibroblast growth factor 23 (FGF23), secreted by osteoblasts and osteocytes, can inhibit bone formation and mineralization. This
Hongqi Zhang +8 more
doaj +1 more source
Frontiers in Cell and Developmental Biology, 2021 Fibroblast growth factor (FGF) 23 is elevated in chronic kidney disease (CKD) to maintain phosphate homeostasis. FGF23 is associated with left ventricular hypertrophy (LVH) in CKD and induces LVH via klotho-independent FGFR4-mediated activation of ...
Maren Leifheit-Nestler +17 more
doaj +1 more source
FGF23, alpha-Klotho and vitamin D mediated calcium-phosphate metabolism in haemodialysis patients [PDF]
Journal of Medical Biochemistry, 2021 Background: Klotho is a protein that acts as a co-receptor for FGF23. FGF23-Klotho axis has great importance regarding the regulation of mineral metabolism by kidneys.
Pasaoglu Ozge Tugce +4 more
doaj +1 more source
Research Models for Studying Vascular Calcification [PDF]
, 2020 Calcification of the vessel wall contributes to high cardiovascular morbidity and mortality. Vascular calcification (VC) is a systemic disease with multifaceted contributing and inhibiting factors in an actively regulated process.
Babic, Milen +4 more
core +1 more source