Results 151 to 160 of about 113,403,989 (177)

Reversal of evolving third-degree atrioventricular block in utero by early detection and combination therapy. [PDF]

open access: yesUltrasound Obstet Gynecol
Lertvutivivat S   +6 more
europepmc   +1 more source

Neutrophil Extracellular Traps Aggravate Injury in Complement-Mediated Thrombotic Microangiopathy. [PDF]

open access: yesJ Am Soc Nephrol
Liu XT   +7 more
europepmc   +1 more source

Functional Properties of Complement Factor H-Related Proteins FHR-3 and FHR-4: Binding to the C3d Region of C3b and Differential Regulation by Heparin

open access: yesFEBS Letters, 1999
The human factor H-related proteins FHR-3 and FHR-4 are members of a family of proteins related to the complement factor H. Here, we report that the two proteins bind to the C3d region of complement C3b. The apparent KA values for the interactions of FHR-
Seppo Meri, Peter F Zipfel, Outi Vaarala
exaly   +2 more sources
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Complement Factor H, FHR-3 and FHR-1 Variants Associate in an Extended Haplotype Conferring Increased Risk of Atypical Hemolytic Uremic Syndrome

Molecular Immunology, 2015
Atypical hemolytic uremic syndrome (aHUS) is a severe thrombotic microangiopathy affecting the renal microvasculature and is associated with complement dysregulation caused by mutations or autoantibodies. Disease penetrance and severity is modulated by inheritance of "risk" polymorphisms in the complement genes MCP, CFH and CFHR1.
Santiago Rodriguez de Córdoba   +2 more
exaly   +3 more sources

Polymorphism of the human factor H-related gene (FHR-1) and of factor H in a West African individual

Immunogenetics, 1995
The human factor H-related 1 (FHR-1) protein is structurally and immunogenically related to the regulatory complement protein factor H (FH). Polymorphism of the FHR-1 gene is indicated by the nucleotide differences as described by the five cDNA clones isolated so far.
C G, Meyer, C, Skerka, P F, Zipfel
openaire   +2 more sources

Complement factor H: sequence analysis of 221 kb of human genomic DNA containing the entire fH, fHR-1 and fHR-3 genes

Molecular Immunology, 2000
Complement factor H (fH) is a member of a family of proteins involved in the regulation of complement activation (RCA). These proteins share a common structural motif, the Short Consensus Repeat (SCR), which is structurally conserved among related genes and between phylogenetically divergent species.
D A, Male   +4 more
openaire   +2 more sources

Progression of geographic atrophy and polymorphisms of genes CFH, BF, C3, FHR 1‐3, FRH3 and ARMS2/HTRA in Age‐Related Macular Degeneration

Acta Ophthalmologica, 2012
AbstractPurpose To determine if genotype is associated with rate of growth of geographic atrophy (GA) in eyes with age‐related macular degeneration (AMD). We assessed the relationship of GA progression, with previously identified genetic variants associated with AMD.Methods A prospective analysis of participants in a controlled clinical trial from 9 ...
S RECALDE   +7 more
openaire   +1 more source

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