Results 91 to 100 of about 30,065 (273)
Advances in Microfluidic Cochlea‐On‐A‐Chip
Advanced Science, EarlyView.This review systematically examines diverse cell sources for inner ear organoids and outlines stepwise induction protocols. Furthermore, it discusses current applications and prospective developments of cochlea‐on‐a‐chip technologies in areas such as deafness modeling, mechanistic studies, and drug evaluation, with particular focus on gene‐therapy drug
Tian Shen +10 more
wiley +1 more source
Poroelasticity of (bio)polymer networks during compression: theory and experiment [PDF]
arXiv, 2019 Soft living tissues like cartilage can be considered as biphasic materials comprised of a fibrous complex biopolymer network and a viscous background liquid. Here, we show by a combination of experiment and theoretical analysis that both the hydraulic permeability and the elastic properties of (bio)polymer networks can be determined with simple ramp ...
arxiv
Advances in Symbiotic Bioabsorbable Devices
Advanced Science, EarlyView.This review focuses on recent advances in bioabsorbable devices. This review concludes innovation at the material, device, and system levels, the significant advances toward biomedical applications. This review discusses and highlights the challenges and trends in symbiotic bioresorbable electronics, and provides a new direction for the development of ...
Chang Zhu +3 more
wiley +1 more source
Multimodal CARS and SHG microscopy for label-free detection of collagen produced by hDFs in fibrin gel [PDF]
arXiv, 2011 Label-free combined CARS and SHG microscopy techniques are used as powerful tool to follow the cells behavior in cell-scaffold construct for regeneration of tissues. Imaging of histological section of hDFs seeded in fibrin gel scaffold and imaging of collagen produced by hDFs in a time course experiment at different culture days (0, 7, 21, 42) is ...
arxiv
Advanced Science, EarlyView.Graphene‐PEDOT:PSS fillers revolutionize soft electronics by transforming jelly‐like materials into skin‐like systems with self‐healing, heat‐responsiveness, and multiplex sensing capabilities. This novel material exhibits exceptional printability, flexibility, and adhesiveness, enabling seamless integration into bioelectronics and tissue‐cyborganic ...
Morteza Alehosseini +7 more
wiley +1 more source
Molecular Mechanism of Transition from Catch-Bond to Slip-Bond in Fibrin [PDF]
arXiv, 2017 The lifetimes of non-covalent A:a knob-hole bonds in fibrin probed with the optical trap-based force-clamp first increases ("catch bonds") and then decreases ("slip bonds") with increasing tensile force. Molecular modeling of "catch-to-slip" transition using the atomic structure of the A:a complex reveals that the movable flap serves as tension ...
arxiv
A review of fibrin and fibrin composites for bone tissue engineering
International Journal of Nanomedicine, 2017 Tissue engineering has emerged as a new treatment approach for bone repair and regeneration seeking to address limitations associated with current therapies, such as autologous bone grafting. While many bone tissue engineering approaches have traditionally focused on synthetic materials (such as polymers or hydrogels), there has been a lot of ...
Thomas J. Webster +4 more
openaire +6 more sources
Advanced Science, EarlyView.Autologous plasma‐derived platelet‐rich fibrin (PRF) is prepared as a protective shield for mesenchymal stem cell spheroids (Sp‐MSCs). PRF forms a fibrin shield to protect Sp‐MSCs from the oxidative stress environment. The nutrients in PRF, particularly the α‐granules, can enhance the repair function of Sp‐MSCs.
Jinglve Zhang +10 more
wiley +1 more source
Advanced Science, EarlyView.Occlusion of tumor blood vessels represents a promising yet challenging approach in cancer treatment. Herein, supramolecularly engineered platelets conjugated with morphology‐transformable nanoparticles is developed for precise tumor embolization. The engineered platelets actively accumulate at tumor sites following induced blood vessel injury.
Junyan Li +9 more
wiley +1 more source