Results 111 to 120 of about 199,538 (306)

Mechanically Robust Biodegradable Stents With Theragenerative Vascular Responses via Combined 3D Printing and Janus Nanoengineering

Advanced Science, EarlyView.
This work introduces a theragenerative 3D‐printed biodegradable stent with Janus nanoarchitecture for spatially controlled vascular healing. A luminal tantalum ion–implanted surface accelerates endothelialization and hemocompatibility, while an abluminal sirolimus/poly‐L‐lactic acid–tantalum layer provides sustained drug release and suppresses smooth ...
Jong Hwa Seo, Dong‐Sung Won, Hyun Lee, Seojoon Bang, Hyeong Seok Kang, Ju Yeong Gwon, Chan Ho Moon, Ji Won Kim, Yubeen Park, Minho Kang, Dong Yun Lee, Donghyun Lim, Kisuk Yang, Gi Doo Cha, Soo‐Hong Lee, Tae‐Sik Jang, Seokbeom Kim, Jun‐Kyu Park, Jung‐Hoon Park, Hyun‐Do Jung   +19 more
wiley   +1 more source

Autologous Fibrin/Bioceramic Scaffold for Bone Tissue Engineering

Aim of experimental study was to evaluate histological response on implantation of synthetic biphasic HAp/TCP bioceramic granules mixed with autologous plasma derived fibrin scaffold in subcutaneous tissue of ...
Šalma, Ilze, Skagers, Andrejs, pilmane, Māra, Zālīte, Vita   +3 more
core  

Ramifications of microglial activation on oligodendrocytes in in vitro models of multiple sclerosis

, 2010
Oligodendrocytes are the principal target of immune attack in multiple sclerosis (MS), where the immune system attacks the myelin sheath, leading to oligodendrocyte demise, compromised axonal saltatory conduction and eventually neuronal degeneration ...
Sevastou, I.
core  

Kinetics of the interaction of desAABB-fibrin monomer with immobilized fibrinogen

, 2006
The soluble and stable fibrin monomer-fibrinogen complex (SF) is well known to be present in the circulating blood of healthy individuals and of patients with thrombotic diseases. However, its physiological role is not yet fully understood. To deepen our
Gruber, H. J., Dietler, Giovanni, Vogel, Monique, Chtcheglova, L. A., Haeberli, André, Chtcheglova, Lilia A, Gruber, Hermann J, Vogel, M., Dietler, G., Haeberli, A.   +9 more
core   +1 more source

Lyophilized Synthetic Platelets: In Vitro Characterization and in Vivo Evaluation in Mouse Thrombocytopenia Model

Advanced Science, EarlyView.
ABSTRACT Platelet transfusions to treat bleeding complications use donor‐derived platelets stored at room‐temperature, that have a shelf‐life of only 5–7 days due to bacterial contamination risks. Cold‐stored and freeze‐dried platelets are being investigated for extending shelf‐life, but these still have the inherent challenge of donor‐dependency.
Ujjal Didar Singh Sekhon, Dante Disharoon, Shrijal S. Desai, Baylee Traylor, Emily Gahagan, Emma Quill, Kristin Aldridge, Norman F. Luc, Sonali Rohiwal, Shruti Raghunathan, Rebecca Ahn, Sana Syed, Alexander Dornback, Bipin Chakravarthy Paruchuri, Andrew Ditto, Susan M. Shea, Philip C. Spinella, Matthew D. Neal, Michael A. Bruckman, Christa L. Pawlowski, Anirban Sen Gupta   +20 more
wiley   +1 more source

A hospital cost analysis of a fibrin sealant patch in soft tissue and hepatic surgical bleeding

, 2016
Mitra Corral,1 Nicole Ferko,2 Andrew Hogan,2 Sarah S Hollmann,2 Gaurav Gangoli,1 Nadine Jamous,3 Jonathan Batiller,1 Richard Kocharian1 1Ethicon BioSurgery, Somerville, NJ, USA; 2Cornerstone Research Group, Burlington, ON, Canada; 3Ethicon Biosurgery ...
Ferko N, Hollmann SS, Jamous N, Corral M, Batiller J, Gangoli G, Hogan A, Kocharian R   +7 more
core  

Harnessing Phase Separation for the Development of High‐Performance Hydrogels

Advanced Science, EarlyView.
ABSTRACT Hydrogels are indispensable for the development of next‐generation bioelectronics, soft robotics, and biomedical devices, where their mechanical properties determine performance and reliability. Among strategies to enhance hydrogel mechanics, phase separation enables controlled heterogeneity resulting in gel networks that are reinforced by ...
Yue Shao, Yiming Ma, Baihao Shao, Molly M. Stevens   +3 more
wiley   +1 more source

Comparison of commercial fibrin sealants in facelift surgery: a prospective study

, 2013
Giovanni Botti,1 Michele Pascali,2 Chiara Botti,1 Florian Bodog,3 Pietro Gentile,2 Valerio Cervelli2 1Villa Bella Clinic, Salò, 2Department of Plastic and Reconstructive Surgery, University of Rome Tor Vergata, Italy; 3University of Oradea, Oradea,
Pascali M, Botti C, Gentile P, Cervelli V, Botti G, Bodog F   +5 more
core  

Dual‐Network Protein Hydrogels Promote Rapid Hemostasis and Immune‐Regulated Scarless Tissue Regeneration

Advanced Science, EarlyView.
A dual‐network protein hydrogel substantially improves hemostasis and scar‐free healing.The adaptive network maintains intimate tissue contact while providing strong wet adhesion, tunable mechanics, and controlled degradation. Concurrent ROS scavenging and M2 polarization suppress fibrotic pathways, preventing scar formation.
Xiaomei Li, Guorui Zhang, Xinyue Wang, Zhongyu Liu, Ling Yang, Yuhan Bao, Min Wei, Yonglin Chen, Yanfei Ma, Wenbo Sheng, Bo Yu, Bin Li   +11 more
wiley   +1 more source

Fibrin scaffold structure and platelet fibrin/fibrinogen binding in CLSM studies.

, 2013
CLSM images were taken 15 minutes after stimulation of diluted PRP with thrombin (1 U/ml) in order to analyze fibrin network formation in the presence of platelets.
Hideto Sano (279018), Tetsumei Urano (279019), Tomasz Brzoska (279016), Yuko Suzuki (279017), Hideo Mogami (124744)   +4 more
core   +1 more source