Results 91 to 100 of about 214,661 (285)

Thermochemical Micro‐Explosion for Prompt Thrombolysis via Proximal Injection of Liquid Alkali Metal

open access: yesAdvanced Science, EarlyView.
We report a micro‐explosive thermochemical thrombolysis (METCT) therapy via injectable liquid alkali metal encapsulated in dimethyl silicone (LAM@oil). METCT enables prompt and safe vascular recanalization within 90 s. Critically, the LAM@oil system demonstrates significantly higher thrombolytic efficacy compared to clinically available thrombolytic ...
Xin Liao   +7 more
wiley   +1 more source

Cell-seeded polyurethane-fibrin structures – A possible system for intervertebral disc regeneration [PDF]

open access: yesEuropean Cells & Materials, 2009
Nowadays, intervertebral disc (IVD) degeneration is one of the principal causes of low back pain involving high expense within the health care system.
C Mauth   +7 more
doaj  

Fibrin-Targeted Polymerized Shell Microbubbles as Potential Theranostic Agents for Surgical Adhesions

open access: yes, 2019
The development of new therapies for surgical adhesions has proven to be difficult as there is no consistently effective way to assess treatment efficacy in clinical trials without performing a second surgery, which can result in additional adhesions. We
Jo Ann Buczek-Thomas (366939)   +19 more
core   +1 more source

Bioinspired Passive Flow Routing to Mitigate Thrombosis in Prosthetic Heart Valves and Cardiovascular Devices

open access: yesAdvanced Science, EarlyView.
Bioinspired passive flow routing mitigates thrombosis in cardiovascular devices by redirecting a small fraction of forward flow into stagnation‐prone regions. Inspired by avian alula and aircraft slat mechanisms, strategically placed routing channels restore washout around mechanical heart valves, reducing low‐shear exposure by four orders of magnitude
Yevgeniy Kreinin   +8 more
wiley   +1 more source

Peptide Bbeta(15-42) preserves endothelial barrier function in shock [PDF]

open access: yes, 2009
Loss of vascular barrier function causes leak of fluid and proteins into tissues, extensive leak leads to shock and death. Barriers are largely formed by endothelial cell-cell contacts built up by VE-cadherin and are under the control of RhoGTPases. Here
George Ignatyev   +25 more
core   +1 more source

In Situ Programmable Modulation of Hydrogel Stiffness for Stage‐Adaptive Bone Regeneration

open access: yesAdvanced Science, EarlyView.
Near‐infrared (NIR) irradiation triggers Ca2+ release from thermoresponsive nanocarriers, enabling in situ stiffening of an adaptive hydrogel from a soft to a stiff state, thereby sequentially supporting mesenchymal stromal cell stemness and osteogenic differentiation for stage‐adaptive bone regeneration.
Yuxin Yang   +5 more
wiley   +1 more source

Platelet reactivity influences clot structure as assessed by fractal analysis of viscoelastic properties

open access: yesPlatelets, 2018
Despite the interwoven nature of platelet activation and the coagulation system in thrombosis, few studies relate both analysis of protein and cellular parts of coagulation in the same population.
Rebecca B. Knowles   +11 more
doaj   +1 more source

Hydraulic Pressure‐Programmed Molecular Transport in Tough Hydrogels

open access: yesAdvanced Science, EarlyView.
Hydraulic pressure is introduced as a programmable parameter for regulating molecular transport in tough hydrogel membranes. Reversing the pressure direction accelerates or slows transport, tuning characteristic transport times over a 65‐fold range while achieving molecular separation and controlled delivery.
Yijie Cheng   +7 more
wiley   +1 more source

Dynamic light scattering study of fine semiflexible fibrin networks

open access: yes, 1997
Fine fibrin networks have been investigated using the dynamic light scattering (DLS) technique. At the shortest delay times, t, the dynamic structure factor s(q,t) is found to depend on time according to an exponential function and, at intermediate delay
De Spirito, Marco, Di Stasio, Enrico
core   +1 more source

Electronic Chip‐Mimetic Medical Implants for Controllable Sonothermal Treatments

open access: yesAdvanced Science, EarlyView.
Inspired by the thermal effect of working electronic chips, which consist of various heterostructures, an sonothermal‐responsive platform has been developed through constructing metal‐semiconductor interface on implants. Biofilm infection and deep vein thrombosis can be successfully treated by controllable ultrasound treatments.
Zhengdong Zhang   +10 more
wiley   +1 more source

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