Results 111 to 120 of about 30,065 (273)

Multiscale Insights of Domain Unfolding in Fibrin Mechanical Response [PDF]

arXiv
Fibrinogen, the monomeric unit of fibrin, the main constituent of blood clot, has a very complex structure. The fibrinogen builds the fibrin fiber and network through the half-staggered packing via knob-hole interaction and the $\alpha$C crosslinkers. Due to its rich structure, the elastic behavior also shows a unique nature of very high stretchability
arxiv  

Fibrin fixes fibrosis [PDF]

Blood, 2016
In this issue of Blood , Joshi et al demonstrate that the interaction between fibrin and α M β 2 on leukocytes reduces the development of liver fibrosis in a mouse model of cholestatic injury ...
openaire   +4 more sources

Polymer Brush‐Based Asymmetric Porous Patch with Excellent Anti‐Bacterial and Anti‐Contamination Properties Enables Infectious Abdominal Wall Defect Repair

Advanced Science, EarlyView.
A zwitterionic asymmetric patch is developed via self‐induced phase separation. The cationic layer exhibits anti‐bacterial efficacy and releases pro‐healing factor, while the zwitterionic hydrogel prevents contamination and visceral adhesion. The strong mechanical interlocking of two layers leads to a high and stable burst pressure tolerance.
Zeping Huang, Weiwen Liang, Binying Peng, Yang Ouyang, Zixin Chen, Mawsoom Mamut, Zhipeng Huang, Hui Wang, Rongkang Huang, Bo Ma, Bingna Zheng, Jian Cai   +11 more
wiley   +1 more source

Programming filamentous network mechanics by compression [PDF]

arXiv, 2016
Fibrous networks are ideal functional materials since they provide mechanical rigidity at low weight. Such structures are omnipresent in natural biomaterials from cells to tissues, as well as in man-made materials from polymeric composites to paper and textiles.
arxiv  

Ueber Zimmtaldehyd als Spaltungsprodukt bei der Fibrin‐Pankreasverdauung [PDF]

, 1880
J. Ossikovszky
openalex   +1 more source

Single‐Cell Analysis Reveals that Vitamin C Inhibits Bone Metastasis of Renal Cancer via Cell Cycle Arrest and Microenvironment Remodeling

Advanced Science, EarlyView.
3D‐cultured renal cancer cells exhibit stem‐like phenotypes and are more efficient in generating bone metastases. Vitamin C treatment can suppress the development of bone metastasis. Single‐cell transcriptomic analysis reveals that vitamin C inhibits metastasis by inducing tumor cell cycle arrest, suppressing osteoclast differentiation, and reducing ...
Jianye Zhang, Qi Zhang, Gang Lin, Ying Wang, Juan Li, Ping Wang, Jie Qi, Yuan Liang, Shiming He, Yanqing Gong, Ninghan Feng, Yang Wang, Yuanyuan Ma, Mei Zhang, Yue Shi, Xuesong Li, Weimin Ci, Liqun Zhou   +17 more
wiley   +1 more source

Mechanical Biomimetic Nanocomposites for Multidimensional Treatment of Arterial Thrombosis

Advanced Science, EarlyView.
In this study, a mechanical biomimetic nanocomposite is developed, guided by photoacoustic imaging, to achieve highly efficient and safe thrombolysis through the synergistic effects of photothermal therapy and pharmacological intervention. Most notably, the nanoparticle improves the microenvironment of arterial thrombi, marked by high shear stress and ...
Ying Li, Qi Xiang, Yan Zhang, Fuxue Luo, Yunfang Wu, Haitao Ran, Yang Cao   +6 more
wiley   +1 more source

AIF1+CSF1R+ MSCs, induced by TNF‐α, act to generate an inflammatory microenvironment and promote hepatocarcinogenesis

Hepatology, EarlyView., 2022
Mesenchymal stem cells subset, educated by TNF‐α, are involved to generate inflammatory microenvironment and promote hepatocarcinogenesis Abstract Background and Aims Increasing evidence suggests that mesenchymal stem cells (MSCs) home to injured local tissues and the tumor microenvironment in the liver.
Chen Zong, Yan Meng, Fei Ye, Xue Yang, Rong Li, Jinghua Jiang, Qiudong Zhao, Lu Gao, Zhipeng Han, Lixin Wei   +9 more
wiley   +1 more source

Suspended Tissue Open Microfluidic Patterning (STOMP)

Advanced Science, EarlyView.
Suspended Tissue Open Microfluidic Patterning (STOMP) is a method that enables precise spatial patterning within a single suspended tissue. By leveraging capillary pinning and open microfluidics, STOMP facilitates the creation of complex tissue interfaces such as diseased‐healthy boundaries and tissue‐tissue junctions. This method integrates mechanical
Amanda J. Haack, Lauren G. Brown, Alex J. Goldstein, Priti Mulimani, Jean Berthier, Asha R. Viswanathan, Irina Kopyeva, Jamison M. Whitten, Ariel Lin, Serena H. Nguyen, Thomas P. Leahy, Ella E. Bouker, Ruby M. Padgett, Natalie A. Mazzawi, Jodie C. Tokihiro, Ross C. Bretherton, Aaliyah Wu, Stephen J. Tapscott, Cole A. DeForest, Tracy E. Popowics, Erwin Berthier, Nathan J. Sniadecki, Ashleigh B. Theberge   +22 more
wiley   +1 more source

Study on the efficacy of compound porcine cerebroside and ganglioside injection in patients with ischemic stroke: A randomized, single‐center, open‐label, prospective study

Ibrain, EarlyView., 2023
Compound porcine perebroside and ganglioside injection (CPCGI) was used to treat ischemic stroke. However, there was no clinical evidence of low‐dose CPCGI. We conducted a clinical study to analyze whether the clinical results of low‐dose and standard‐dose CPCGI in patients with ischemic stroke were different.
Ya Chen, Xia Zhang, Hai‐Qing Zhang, Zhong Luo, Xue‐Jiao Zhou, Tao Liang, Fei Yang, Jun Zhang, Zu‐Cai Xu   +8 more
wiley   +1 more source