Results 121 to 130 of about 340,737 (387)
Coagulation and anticoagulation in idiopathic pulmonary fibrosis [PDF]
Idiopathic pulmonary fibrosis (IPF) is an incurable, progressive interstitial lung disease with a prognosis that is worse than that of many cancers. Epidemiological studies have demonstrated a link between IPF and thrombotic vascular events.
Crooks, Michael G., Hart, Simon P.
core +3 more sources
Fibrin and D-dimer bind to monomeric GPVI.
Fibrin has recently been shown to activate platelets through the immunoglobulin receptor glycoprotein VI (GPVI). In the present study, we show that spreading of human platelets on fibrin is abolished in patients deficient in GPVI, confirming that fibrin ...
Marie-Blanche Onselaer+13 more
semanticscholar +1 more source
Bone fracture healing is a complex, timely orchestrated scenario involving multiple cell types and a plethora of cytokines and regulatory factors. To gain further insight, an in vitro model to a) study macrophage polarization under mechanical load in a fibrin hydrogel and b) subsequently assess the effect of conditioned media derived from macrophages ...
Anne Géraldine Guex+4 more
wiley +1 more source
Role of immunoturbidimetric plasma fibrin D-dimer test in patients with coronary artery disease as well as ischemic heart disease in emergency medicine [PDF]
The aim of the present was to assess the value of the ELISA D-dimer (hemostatic marker) assay in patients with coronary artery disease as well as ischemic heart disease presenting to the emergency department with chest pain syndrome. Methods: We measured
Ajay K. Singh , Vikas Gupta, Neelima Singh, Sanjeev K. Singh , Nivedita Singh, Arun Raiza, Harshverdhan Singh , Int J Cur Biomed Phar Res.
core
Nonlinear Elasticity in Biological Gels [PDF]
Unlike most synthetic materials, biological materials often stiffen as they are deformed. This nonlinear elastic response, critical for the physiological function of some tissues, has been documented since at least the 19th century, but the molecular ...
AD Karakaplan+33 more
core +2 more sources
Platelet concentrates for topical and infiltrative use - commonly termed Platetet-Rich Plasma (PRP) or Platelet-Rich Fibrin (PRF) - are used or tested as surgical adjuvants or regenerative medicine preparations in most medical fields, particularly in ...
D. M. Dohan Ehrenfest+5 more
semanticscholar +1 more source
Progress of Immune‐Inducible Biomaterials for Post‐Ablation Cancers
The presence of residual tumors after ablative therapies poses a significant challenge, generally resulting in recurrence and metastases. This review offers a concise overview of immune‐inducible biomaterials from the perspective of the cancer‐immunity cycle, and how they enhance antitumor immunity through diverse mechanisms following ablative ...
Shuangshuang Zhao+7 more
wiley +1 more source
Platelet glycoprotein VI binds to polymerized fibrin and promotes thrombin generation.
Fibrin, the coagulation end product, consolidates the platelet plug at sites of vascular injury and supports the recruitment of circulating platelets.
E. Mammadova-Bach+11 more
semanticscholar +1 more source
Multifunctional Biomedical Devices with Closed‐Loop Systems for Precision Therapy
This review explores two major types of closed‐loop therapeutic systems: self‐sustained and externally triggered. It highlights recent advances in stimuli‐responsive materials, integrated bioelectronics, and data‐driven control strategies, offering insight into emerging strategies for personalized, responsive drug delivery.
Yixuan Leng, Rujie Sun
wiley +1 more source