Results 11 to 20 of about 30,065 (273)

Composition and Organization of Acute Ischemic Stroke Thrombus: A Wealth of Information for Future Thrombolytic Strategies

open access: yesFrontiers in Neurology, 2022
During the last decade, significant progress has been made in understanding thrombus composition and organization in the setting of acute ischemic stroke (AIS).
Jean-Philippe Desilles   +18 more
doaj   +1 more source

Changes in Elastic Moduli of Fibrin Hydrogels Within the Myogenic Range Alter Behavior of Murine C2C12 and Human C25 Myoblasts Differently

open access: yesFrontiers in Bioengineering and Biotechnology, 2022
Fibrin hydrogels have proven highly suitable scaffold materials for skeletal muscle tissue engineering in the past. Certain parameters of those types of scaffolds, however, greatly affect cellular mechanobiology and therefore the myogenic outcome.
Janine Tomasch   +17 more
doaj   +1 more source

Quantification of Plasma Fibrinogen Degradation Products in Areca Nut Chewers with and without Oral Submucous Fibrosis [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2014
Introduction: Fibrinogen degradation products (FDPs) are the products that are released from fibrin/fibrinogen. Recently, it has been observed that these FDPs have been identified in the plasma of OSMF patients. Areca nut being the major aetiological
Sonia Gupta   +3 more
doaj   +1 more source

Comparison of Fibrin and PLGA/fibrin Scaffolds for Chondrogenesis of Human Adipose Derived Stem Cells by Icariin [PDF]

open access: yesJournal of Kerman University of Medical Sciences, 2020
Background: Recently, cartilage tissue engineering is the best candidate for regeneration of cartilage defects. We evaluated the potential of fibrin and PLGA/fibrin scaffolds in providing a suitable environment for growth and chondrogenic differentiation
Batool Hashemibeni   +5 more
doaj   +1 more source

Fibrin‐specific poly(N‐isopropylacrylamide) nanogels for targeted delivery of tissue‐type plasminogen activator to treat thrombotic complications are well tolerated in vivo

open access: yesBioengineering & Translational Medicine, 2022
Targeted drug delivery for maintaining blood fluidity can reduce the risks associated with systemic anticoagulants that can lead to off‐target bleeding. Recently, there has been much interest in targeted delivery of tissue‐type plasminogen activator (tPA)
Emily P. Mihalko   +6 more
doaj   +1 more source

Establishment of A Three-Dimensional Culture Condition for The U266 Cell Line Based on Peripheral Blood Plasma-Derived Fibrin Gels [PDF]

open access: yesCell Journal, 2023
Objective: The study of pathophysiology as well as cellular and molecular aspects of diseases, especially cancer,requires appropriate disease models. In vitro three-dimensional (3D) structures attracted more attention to recapitulatediseases rather than ...
Mahshid Jomehpour   +4 more
doaj   +1 more source

Electromagnetically Induced Distortion of a Fibrin Matrix with Embedded Microparticles [PDF]

open access: yesJournal of Mechanics in Medicine and Biology, Vol. 18, No. 02, 1850016 (2018), 2016
Blood clots occur in the human body when they are required to prevent bleeding. In pathological states such as diabetes and sickle cell disease, blood clots can also form undesirably due to hypercoagulable plasma conditions. With the continued effort in developing fibrin therapies for potential life-saving solutions, more mechanical modeling is needed ...
arxiv   +1 more source

Enhanced Thrombotic Responses Are Associated With Striatin Deficiency and Aldosterone

open access: yesJournal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2021
Background In addition to its role on blood pressure, aldosterone (ALDO) also affects the hemostatic system leading to increased experimental thrombosis. Striatin is an intermediate in the rapid, nongenomic actions of ALDO. Striatin heterozygote knockout
Anna Gromotowicz‐Poplawska   +6 more
doaj   +1 more source

Coarse Grain Molecular Dynamics Simulation of Fibrin Polymerization [PDF]

open access: yesJ Mol Model 24, 109 (2018), 2017
Studies suggests that patients with deep vein thrombosis and diabetes often have hy-per coagulable blood plasma leading to higher chances of forming thromboembolisms by the rupture of blood clots, which may lead to stroke and death. Despite the advances in the field of blood clot formation and lysis research, the change in mechanical properties and its
arxiv   +1 more source

Fibrin deposition on bovine pericardium tissue used for bioprosthetic heart valve drives its calcification

open access: yesFrontiers in Cardiovascular Medicine, 2023
BackgroundBioprosthetic heart valves (BHVs) are less thrombogenic than mechanical prostheses; however, BHV thrombosis has been proposed as a risk factor for premature BHV degeneration.ObjectivesWe aimed to explore whether fibrin deposition on bovine ...
Bastien Poitier   +11 more
doaj   +1 more source

Home - About - Disclaimer - Privacy