Results 11 to 20 of about 370,815 (388)
Fibrin clot properties in cardiovascular disease: from basic mechanisms to clinical practice
Cardiovascular Research, 2023 Fibrinogen conversion into insoluble fibrin and the formation of a stable clot is the final step of the coagulation cascade. Fibrin clot porosity and its susceptibility to plasmin-mediated lysis are the key fibrin measures, describing the properties of ...
M. Ząbczyk, R. Ariëns, A. Undas
semanticscholar +1 more source
Technological advances in fibrin for tissue engineering
Journal of Tissue Engineering, 2023 Fibrin is a promising natural polymer that is widely used for diverse applications, such as hemostatic glue, carrier for drug and cell delivery, and matrix for tissue engineering.
R. Sanz-Horta +7 more
semanticscholar +1 more source
Cardiovascular Diabetology, 2022 Background Fibrin(ogen) amyloid microclots and platelet hyperactivation previously reported as a novel finding in South African patients with the coronavirus 2019 disease (COVID-19) and Long COVID/Post-Acute Sequelae of COVID-19 (PASC), might form a ...
E. Pretorius +8 more
semanticscholar +1 more source
Biochemical Journal, 2022 Post-acute sequelae of COVID (PASC), usually referred to as ‘Long COVID’ (a phenotype of COVID-19), is a relatively frequent consequence of SARS-CoV-2 infection, in which symptoms such as breathlessness, fatigue, ‘brain fog’, tissue damage, inflammation,
D. Kell, G. J. Laubscher, E. Pretorius
semanticscholar +1 more source
Advances in Fibrin-Based Materials in Wound Repair: A Review
Molecules, 2022 The first bioprocess that occurs in response to wounding is the deterrence of local hemorrhage. This is accomplished by platelet aggregation and initiation of the hemostasis cascade.
Ilker S. Bayer
semanticscholar +1 more source
Fibrin is a critical regulator of neutrophil effector function at the oral mucosal barrier
Science, 2021 Description Fibrin gums up the works Plasmin is an abundant plasma protease that cleaves and deactivates the clot-associated protein fibrin. Human deficiencies in plasmin and its inactive proenzyme form, plasminogen (PLG), cause severe inflammation in ...
L. M. Silva +23 more
semanticscholar +1 more source
The Role of Fibrin(ogen) in Wound Healing and Infection Control
Seminars in Thrombosis and Hemostasis, 2021 Fibrinogen, one of the most abundant plasma proteins playing a key role in hemostasis, is an important modulator of wound healing and host defense against microbes.
Katherine J. Kearney +2 more
semanticscholar +1 more source
Fibrin(ogen) in human disease: both friend and foe
Haematologica, 2020 Fibrinogen is an abundant protein synthesized in the liver, present in human blood plasma at concentrations ranging from 1.5-4 g/L in healthy individuals with a normal half-life of 3-5 days. With fibrin, produced by thrombin-mediated cleavage, fibrinogen
Rui Vilar +3 more
semanticscholar +1 more source
Fibrin Facilitates Mesenchymal Stem Cells to Ameliorate Rats with Polycystic Ovary Syndrome
Applied Sciences, 2020 Polycystic ovarian syndrome (PCOS) is a ubiquitous hormonal disorder and induces female infertility and heterogeneous syndromes, for which there is still no effective treatment.
Yuanyuan Li +5 more
doaj +1 more source
Advanced NanoBiomed Research, 2021 3D bioprinting can produce complex human tissue mimics using stem cells (SCs). Herein, cylindrical constructs containing human‐induced pluripotent stem cell (hiPSC)‐derived neural progenitor cells (NPCs) encapsulated in a fibrin‐based bioink containing ...
Laura De la Vega +5 more
doaj +1 more source