Results 11 to 20 of about 340,737 (387)
Not fibrin(ogen), but fibrinogen or fibrin [PDF]
In this issue of Blood, Prasad et al describe a mouse model with a mutation in the Aα chain of fibrinogen such that no fibrin polymer is formed in vivo, allowing for the first time the differentiation of the role of fibrinogen vs fibrin oligomer or polymer in antimicrobial host defense and in hemostasis/thrombosis.
Rustem I. Litvinov, John W. Weisel
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Analysis of point model of fibrin polymerization [PDF]
Functional modeling of blood clotting and fibrin-polymer mesh formation is of a significant value for medical and biophysics applications. Despite the fact of some discrepancies present in simplified functional models their results are of the great ...
Anna Arkadievna Andreeva+2 more
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Force-Bioreactor for Assessing Pharmacological Therapies for Mechanobiological Targets
Tissue fibrosis is a major health issue that impacts millions of people and is costly to treat. However, few effective anti-fibrotic treatments are available. Due to their central role in fibrotic tissue deposition, fibroblasts and myofibroblasts are the
Austin J. Scholp+9 more
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Fibrin hydrogels have proven highly suitable scaffold materials for skeletal muscle tissue engineering in the past. Certain parameters of those types of scaffolds, however, greatly affect cellular mechanobiology and therefore the myogenic outcome.
Janine Tomasch+17 more
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INFLUENCE OF FIBRIN D AND DD FRAGMENTS ON FIBRINOGEN AND FIBRINOGEN FRAGMENT X POLYMERIZATION INITIATED BY THROMBIN OR ANCISTRON [PDF]
Aim. Study of the role of the complex between the ?C region and the B?N domain in the initial stages of fibrin polymerization has been investigated. Materials and Methods.
Tsap P. Yu.+5 more
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During the last decade, significant progress has been made in understanding thrombus composition and organization in the setting of acute ischemic stroke (AIS).
Jean-Philippe Desilles+18 more
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Establishment of A Three-Dimensional Culture Condition for The U266 Cell Line Based on Peripheral Blood Plasma-Derived Fibrin Gels [PDF]
Objective: The study of pathophysiology as well as cellular and molecular aspects of diseases, especially cancer,requires appropriate disease models. In vitro three-dimensional (3D) structures attracted more attention to recapitulatediseases rather than ...
Mahshid Jomehpour+4 more
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Targeted drug delivery for maintaining blood fluidity can reduce the risks associated with systemic anticoagulants that can lead to off‐target bleeding. Recently, there has been much interest in targeted delivery of tissue‐type plasminogen activator (tPA)
Emily P. Mihalko+6 more
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Actively Driven Fluctuations in a Fibrin Network
Understanding force propagation through the fibrous extracellular matrix can elucidate how cells interact mechanically with their surrounding tissue.
Qingda Hu+17 more
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Comparison of Fibrin and PLGA/fibrin Scaffolds for Chondrogenesis of Human Adipose Derived Stem Cells by Icariin [PDF]
Background: Recently, cartilage tissue engineering is the best candidate for regeneration of cartilage defects. We evaluated the potential of fibrin and PLGA/fibrin scaffolds in providing a suitable environment for growth and chondrogenic differentiation
Batool Hashemibeni+5 more
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