Results 21 to 30 of about 281,387 (291)

Fibrin Facilitates Mesenchymal Stem Cells to Ameliorate Rats with Polycystic Ovary Syndrome

open access: yesApplied Sciences, 2020
Polycystic ovarian syndrome (PCOS) is a ubiquitous hormonal disorder and induces female infertility and heterogeneous syndromes, for which there is still no effective treatment.
Yuanyuan Li   +5 more
doaj   +1 more source

Impaired endogenous fibrinolysis at high shear using a point-of-care test in STEMI is associated with alterations in clot architecture [PDF]

open access: yes, 2019
© The Author(s) 2019Impaired endogenous fibrinolysis is an adverse prognostic biomarker in acute coronary syndrome (ACS). Abnormally dense in vitro fibrin thrombi have been demonstrated in ACS patients and related to hypofibrinolysis using cumbersome ...
A Undas   +12 more
core   +3 more sources

Fibrinogen, Fibrinogen-like 1 and Fibrinogen-like 2 Proteins, and Their Effects

open access: yesBiomedicines, 2022
Fibrinogen (Fg) and its derivatives play a considerable role in many diseases. For example, increased levels of Fg have been found in many inflammatory diseases, such as Alzheimer’s disease, multiple sclerosis, traumatic brain injury, rheumatoid ...
Nurul H. Sulimai   +2 more
doaj   +1 more source

Quantitative structural mechanobiology of platelet-driven blood clot contraction. [PDF]

open access: yes, 2017
Blood clot contraction plays an important role in prevention of bleeding and in thrombotic disorders. Here, we unveil and quantify the structural mechanisms of clot contraction at the level of single platelets.
Alber, Mark S   +3 more
core   +2 more sources

Direct Perfusion Improves Redifferentiation of Human Chondrocytes in Fibrin Hydrogel with the Deposition of Cartilage Pericellular Matrix

open access: yesApplied Sciences, 2021
Articular cartilage has limited potential for self-repair, and cell-based strategies combining scaffolds and chondrocytes are currently used to treat cartilage injuries.
Alexandre Dufour   +2 more
doaj   +1 more source

Fibrin and Fibrinolytic Enzyme Cascade in Thrombosis: Unravelling the Role

open access: yesLife, 2023
Blood clot formation in blood vessels (thrombosis) is a major cause of life-threatening cardiovascular diseases. These clots are formed by αA-, βB-, and ϒ-peptide chains of fibrinogen joined together by isopeptide bonds with the help of blood coagulation
Rajni Singh   +3 more
doaj   +1 more source

3D Bioprinting Human‐Induced Pluripotent Stem Cells and Drug‐Releasing Microspheres to Produce Responsive Neural Tissues

open access: yesAdvanced NanoBiomed Research, 2021
3D bioprinting can produce complex human tissue mimics using stem cells (SCs). Herein, cylindrical constructs containing human‐induced pluripotent stem cell (hiPSC)‐derived neural progenitor cells (NPCs) encapsulated in a fibrin‐based bioink containing ...
Laura De la Vega   +5 more
doaj   +1 more source

Fibrin with Laminin-Nidogen Reduces Fibrosis and Improves Soft Palate Regeneration Following Palatal Injury

open access: yesBiomolecules, 2021
This study aimed to analyze the effects of fibrin constructs enhanced with laminin-nidogen, implanted in the wounded rat soft palate. Fibrin constructs with and without laminin-nidogen were implanted in 1 mm excisional wounds in the soft palate of 9-week-
Doris H. Rosero Salazar   +5 more
doaj   +1 more source

Allogeneic Stem Cells Alter Gene Expression and Improve Healing of Distal Limb Wounds in Horses. [PDF]

open access: yes, 2017
Distal extremity wounds are a significant clinical problem in horses and humans and may benefit from mesenchymal stem cell (MSC) therapy. This study evaluated the effects of direct wound treatment with allogeneic stem cells, in terms of gross, histologic,
Aristizobal, Fabio A   +11 more
core   +1 more source

Fibrin-Targeted Nanoparticles for Finding, Visualizing and Characterizing Blood Clots in Acute Ischemic Stroke

open access: yesPharmaceutics, 2022
Recanalization of the occluded artery is the gold standard treatment for acute ischemic stroke, which includes enzymatic fibrinolytic treatment with the use of recombinant tissue plasminogen activators (rtPAs) to disrupt the occluding clot, the use of ...
María Luz Alonso-Alonso   +9 more
doaj   +1 more source

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