Results 21 to 30 of about 214,661 (285)
Not fibrin(ogen), but fibrinogen or fibrin [PDF]
Blood, 2015 In this issue of Blood, Prasad et al describe a mouse model with a mutation in the Aα chain of fibrinogen such that no fibrin polymer is formed in vivo, allowing for the first time the differentiation of the role of fibrinogen vs fibrin oligomer or polymer in antimicrobial host defense and in hemostasis/thrombosis.
Rustem I. Litvinov, John W. Weisel
openaire +2 more sources
Cellular mechanisms of fibrin (ogen): insight from neurodegenerative diseases
Frontiers in Neuroscience, 2023 Neurodegenerative diseases are prevalent and currently incurable conditions that progressively impair cognitive, behavioral, and psychiatric functions of the central or peripheral nervous system. Fibrinogen, a macromolecular glycoprotein, plays a crucial
Tingting Wen, Zhaohui Zhang
doaj +1 more source
Effects of Antiplatelet Drugs on Platelet-Dependent Coagulation Reactions
Biomolecules, 2023 Activated platelets are involved in blood coagulation by exposing phosphatidylserine (PS), which serves as a substrate for assembling coagulation complexes.
Ivan A. Muravlev +6 more
doaj +1 more source
Journal of Functional Biomaterials, 2023 A major challenge for future drug development comprises finding alternative models for drug screening. The use of animal models in research is highly controversial, with an ongoing debate on their ethical acceptability.
Bianca Bindi +4 more
doaj +1 more source
Bioengineering, 2020 We previously reported that corneal fibroblasts within 3D fibrin matrices secrete, bind, and organize fibronectin into tracks that facilitate cell spreading and migration.
Miguel Miron-Mendoza +4 more
doaj +1 more source
Enzymatic Hydrolysis of Marine Collagen and Fibrinogen Proteins in the Presence of Thrombin
Marine Drugs, 2020 Enzymatic hydrolysis of native collagen and fibrinogen was carried out under comparable conditions at room temperature. The molecular weight parameters of proteins before and after hydrolysis by thrombin were monitored by gel-penetrating chromatography ...
Ludmila L. Semenycheva +5 more
doaj +1 more source
Clinical and Translational Allergy, 2021 Background Urticarial vasculitis (UV) is defined by long‐lasting urticarial lesions combined with the histopathologic findings of leukocytoclastic vasculitis.
Viktoria Puhl +10 more
doaj +1 more source
Evaluation of Plasma Fibrinogen Degradation Products and Total Serum Protein Concentration in Oral Submucous Fibrosis [PDF]
Journal of Clinical and Diagnostic Research, 2014 Background: Oral submucous fibrosis (OSMF) is a potentially malignant disorder with a multifactorial etiology. Malnutrition is a major problem for the inhabitants of most countries where OSMF is prevalent.
Megha Kadani +6 more
doaj +1 more source
Fibrinogen binds to nontoxigenic and toxigenic Corynebacterium diphtheriae strains
Memorias do Instituto Oswaldo Cruz, 2010 The production of fibrinous exudates may play an important role in determining the outcome of bacterial infection. Although pseudomembrane formation is a characteristic feature of diphtheria, little is known about the fibrinogen (Fbn)-binding properties ...
Priscila Soares Sabbadini +9 more
doaj +1 more source
Fibrin Facilitates Mesenchymal Stem Cells to Ameliorate Rats with Polycystic Ovary Syndrome
Applied Sciences, 2020 Polycystic ovarian syndrome (PCOS) is a ubiquitous hormonal disorder and induces female infertility and heterogeneous syndromes, for which there is still no effective treatment.
Yuanyuan Li +5 more
doaj +1 more source