Results 91 to 100 of about 27,802 (306)

Prediction of arterial extravasation in pelvic fracture patients with stable hemodynamics using coagulation biomarkers

open access: yesWorld Journal of Emergency Surgery, 2019
Background Determining the presence of an active arterial hemorrhage in the acute phase is important as a treatment strategy in patients with pelvic fracture. The purpose of this study was to evaluate whether coagulation biomarkers could predict arterial
Makoto Aoki   +4 more
doaj   +1 more source

A Circuit of Mechanically Regulated Transcription Factors Balances Regenerative and Fibrotic Memory of Mesenchymal Stromal Cells

open access: yesAdvanced Science, EarlyView.
Producing MSCs on rigid culture substrates induces a scar‐making phenotype, jeapordizing therapeutic success. ‘Tissue‐soft’ surfaces prevent MSC fibrogenesis and preserve regenerative traits. An epigenetic network, driven by HOXA11 and SALL1, maintains ‘soft memory’ by keeping chromatin open in relaxed MSCs, promoting anti‐fibrotic programs.
Fereshteh Sadat Younesi   +7 more
wiley   +1 more source

Fibrin and Fibrinogen Degradation Products in Chronic Subdural Hematoma

open access: yesNeurologia medico-chirurgica, 1975
Fibrin and fibrinogen degradation products (FDP) were examined in 30 cases of chronic subdural hematoma. Fibrinogen was not found in the contents of subdural hematoma in 29 cases, and only a small amount of fibrinogen was detected in the remaining case. The liquefied hematoma content was not coagulated by the addition of thrombin.
H, Ito, T, Komai, S, Yamamoto
openaire   +3 more sources

The Role of Iron-Induced Fibrin in the Pathogenesis of Alzheimer’s Disease and the Protective Role of Magnesium [PDF]

open access: yes, 2013
Amyloid hypothesis of Alzheimer’s disease (AD) has recently been challenged by the increasing evidence for the role of vascular and hemostatic components that impair oxygen delivery to the brain.
Lipinski, Boguslaw, Pretorius, Etheresia
core   +3 more sources

FGL2‐HDAC11 Drives Immunothrombosis via NETs‐Mediated Endothelial Capillarization in MASLD Fibrosis

open access: yesAdvanced Science, EarlyView.
ABSTRACT Metabolic dysfunction–associated steatotic liver disease (MASLD) is frequently accompanied by hepatic fibrosis and systemic cardiovascular complications; however, the mechanistic interplay between coagulation abnormalities and disease progression remains poorly defined.
Xitang Li   +16 more
wiley   +1 more source

An Evaluation of Hemostatic Dysregulation in Canine Multicentric Lymphoma

open access: yesAnimals
Multiple hemostatic abnormalities are associated with paraneoplastic syndrome and some malignant tumors. Lymphoma is the most common hematopoietic neoplasm in dogs, sometimes associated with hemostatic changes.
Maria Ludovica Messina   +4 more
doaj   +1 more source

Clotting activation and impairment of fibrinolysis in malignancy [PDF]

open access: yes, 1989
Different coagulation and fibrinolysis parameters were investigated in 149 patients with metastatic and non-metastatic tumours and results were compared with those obtained in a healthy population.
Cuesta, B. (Braulia)   +6 more
core   +1 more source

Elevated fibrinogen and fibrin degradation product are associated with poor outcome in COVID-19 patients: A meta-analysis [PDF]

open access: green, 2020
Johanes Nugroho   +6 more
openalex   +1 more source

Mechanoadaptation via Myosin Cytoplasmic Redistribution Protects Circulating Tumor Cells From Shear‐induced Death During Hematogenous Dissemination

open access: yesAdvanced Science, EarlyView.
This study investigates how CTCs survive varying shear stress during hematogenous metastasis. We uncover a self‐protection mechanism, by which non‐adherent CTCs adapt to high shearing milieu through accumulated cytoplasmic myosin‐mediated disruption of myosin‐actin binding, attenuating force transmission into chromatin to protect CTCs from shear ...
Cunyu Zhang   +10 more
wiley   +1 more source

COVID-19 Associated Coagulopathy and Implications for its Treatment

open access: yesActa Medica Bulgarica, 2020
The SARS-CoV-2 coronavirus (COVID-19) pandemic is due to lack of prior immunity and there is no certain management, regarding the complications of this viral illness. The target organ for COVID-19 infection are the lungs.
Cherneva Zh., Cherneva R.
doaj   +1 more source

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