Results 101 to 110 of about 27,802 (306)

Role of immunoturbidimetric plasma fibrin D-dimer test in patients with coronary artery disease as well as ischemic heart disease in emergency medicine [PDF]

, 2011
The aim of the present was to assess the value of the ELISA D-dimer (hemostatic marker) assay in patients with coronary artery disease as well as ischemic heart disease presenting to the emergency department with chest pain syndrome. Methods: We measured
Ajay K. Singh , Vikas Gupta, Neelima Singh, Sanjeev K. Singh , Nivedita Singh, Arun Raiza, Harshverdhan Singh , Int J Cur Biomed Phar Res.
core  

Cyclo19,31[D-Cys19]-uPA19-31 is a potent competitive antagonist of the interaction of urokinase-type plasminogen activator with its receptor (CD87) [PDF]

, 2001
Urokinase-type plasminogen activator (uPA) represents a central molecule in pericellular proteolysis and is implicated in a variety of physiological and pathophysiological processes such as tissue remodelling, wound healing, tumor invasion, and ...
Arroyo de Prada, Nuria, Bürgle, Markus, Degitz, Klaus, Kellermann, Josef, Kessler, Horst, Magdolen, Viktor, Riemer, Christoph, Schmiedeberg, Niko, Schmitt, Manfred, Schroeck, Florian, Wilhelm, Olaf G.   +10 more
core   +1 more source

Early Detection and Inhibition of Post‐Surgical Cancer Recurrence by Synthetic Extracellular Vesicles

Advanced Science, EarlyView.
An implantable hydrogel is designed to hold gene transfection agents engineered to turn early recurrent tumor cells into generators of synthetic EVs. These synthetic EVs can express engineered miR‐26a (E‐miR‐26a) for highly sensitive detection and PD‐1 (a PD‐L1‐blocking agent) for therapeutic intervention, thereby enabling early detection and ...
Junli Zhang, Wenjia Chang, Ruolin Hu, Peiyan Su, Qin Zhou, Yanan Li, Zhenzhong Zhang, Kaixiang Zhang   +7 more
wiley   +1 more source

Assessment of Migration of Human MSCs through Fibrin Hydrogels as a Tool for Formulation Optimisation [PDF]

, 2018
Control of cell migration is fundamental to the performance of materials for cell delivery, as for cells to provide any therapeutic effect, they must migrate out from the delivery material.
Dalgarno, Kenneth, Gentile, Piergiorgio, Marina Ferreira, Ana, Partridge, Simon, Salam, Nasseem, Toumpaniari, Sotiria   +5 more
core   +1 more source

Mechanically Robust Biodegradable Stents With Theragenerative Vascular Responses via Combined 3D Printing and Janus Nanoengineering

Advanced Science, EarlyView.
This work introduces a theragenerative 3D‐printed biodegradable stent with Janus nanoarchitecture for spatially controlled vascular healing. A luminal tantalum ion–implanted surface accelerates endothelialization and hemocompatibility, while an abluminal sirolimus/poly‐L‐lactic acid–tantalum layer provides sustained drug release and suppresses smooth ...
Jong Hwa Seo, Dong‐Sung Won, Hyun Lee, Seojoon Bang, Hyeong Seok Kang, Ju Yeong Gwon, Chan Ho Moon, Ji Won Kim, Yubeen Park, Minho Kang, Dong Yun Lee, Donghyun Lim, Kisuk Yang, Gi Doo Cha, Soo‐Hong Lee, Tae‐Sik Jang, Seokbeom Kim, Jun‐Kyu Park, Jung‐Hoon Park, Hyun‐Do Jung   +19 more
wiley   +1 more source

Does the evaluation of coagulation factors contribute to etiological diagnosis of pleural effusions?

Clinics, 2009
OBJECTIVE: The aim of this study was to identify the participation of the coagulation system in the differential diagnosis of pleural effusions. INTRODUCTION: Imbalance between immunologic and metabolic factors triggers a sequence of events resulting in ...
Marcelo Alexandre Costa Vaz, Francisco Suso Vargas, Felipe Costa de Andrade Marinho, Élbio Antonio D'Amico, Tânia Rubia Flores Rocha, Lisete Ribeiro Teixeira   +5 more
doaj   +1 more source

Dual‐Network Protein Hydrogels Promote Rapid Hemostasis and Immune‐Regulated Scarless Tissue Regeneration

Advanced Science, EarlyView.
A dual‐network protein hydrogel substantially improves hemostasis and scar‐free healing.The adaptive network maintains intimate tissue contact while providing strong wet adhesion, tunable mechanics, and controlled degradation. Concurrent ROS scavenging and M2 polarization suppress fibrotic pathways, preventing scar formation.
Xiaomei Li, Guorui Zhang, Xinyue Wang, Zhongyu Liu, Ling Yang, Yuhan Bao, Min Wei, Yonglin Chen, Yanfei Ma, Wenbo Sheng, Bo Yu, Bin Li   +11 more
wiley   +1 more source

Influence of high-dose aprotinin treatment on blood loss and coagulation patterns in open-heart surgery [PDF]

, 1990
Intraoperative administration of the proteinase Inhibitor aprotinin causes reduction in blood loss and homologous blood requirement in patients undergoing cardiac surgery.
Baranky, A., Dietrich, W., Jochum, Marianne, Schramm, Wolfgang, Sebening, F., Spannagl, Michael, Wendt, P.   +6 more
core  

Hydrogel-based microfluidics for vascular tissue engineering [PDF]

, 2016
In this work, we have explored 3-D co-culture of vasculogenic cells within a synthetically modified fibrin hydrogel. Fibrinogen was covalently linked with PEG-NHS in order to improve its degradability resistance and physico-optical properties.
Bagratashvili, Victor N., Chichkov, Boris, Deiwick, Andrea, Kiyan, Roman, Koroleva, Anastasia, Kufelt, Olga, Narayan, Roger, Nguyen, Alexander, Scheper, Thomas, Shpichka, Anastasia, Timashev, Peter   +10 more
core   +2 more sources

Development of a Human 3D Immune‐Competent Neurovascular Model Enabling Time‐Resolved Monitoring of Neuroinflammatory Dynamics and Neuroimmune Interactions

Advanced Science, EarlyView.
Neuroinflammation alters blood–brain barrier integrity and contributes to neurological disorders, yet existing models lack human immune complexity. This study presents a 3D, immune‐responsive platform that reconstructs key neurovascular components and enables real‐time monitoring.
Pavlo Gordiichuk, Jing Bai, Olurotimi A. Bolonduro, Andrew M. Silverman, Robert Madison Green, Jason H. Lasser, Paul W. Fleming, Lishomwa C. Ndhlovu, James F. Saunders, Dmitry Shvartsman   +9 more
wiley   +1 more source