Results 121 to 130 of about 3,801,413 (236)

Cardiovascular Diseases: Exploring Epidemiology, Pathophysiology, Risk Factors, and Medicinal Plant‐Based Therapies: A Narrative Review

Health Science Reports, Volume 9, Issue 9, September 2026.
ABSTRACT Background and Aims Cardiovascular diseases (CVDs) remain the leading cause of global morbidity and mortality, encompassing coronary artery disease, hypertension, heart failure, and cerebrovascular disorders. The global burden of CVD continues to rise, driven by complex interactions among endothelial dysfunction, oxidative stress, inflammation,
Nawfal Hasan Siam, Umme Halima Mithila, Sadia Alam Tisha, Hridoy Saha, Ayesha Binte Mahbub, Farhan Nizam, Johirul Islam, Noushin Tabasumma, Md. Mazharul Islam Chowdhury   +8 more
wiley   +1 more source

Measuring plasma fibrinogen levels in patients with liver cirrhosis. The occurrence of proteolytic fibrin(ogen) degradation products and their influence on several fibrinogen assays

, 1995
In patients with liver cirrhosis the fibrinogen molecule is under constant attack of various proteolytic enzymes, which might affect results of the different assay systems for fibrinogen.
Nieuwenhuizen, W., Knot, E.A.R., Buuren, H.R. van, Maat, M.P.M. de, Swart, G.R.   +4 more
core  

Systemic impact of intramuscular snake envenomation and intravenous immunoglobulin‐based antivenom treatment on murine plasma proteome and peptidome

Protein Science, Volume 35, Issue 9, September 2026.
Abstract Snake envenomation remains a critical global public health challenge. In Brazil, the genus Bothrops is responsible for most accidents, typically resulting in coagulopathy, hemorrhage, and renal failure. Despite its clinical prevalence, the molecular mechanisms driving plasma protein disturbances remain poorly understood.
Bianca C. S. C. de Barros, Alison F. A. Chaves, Mariana S. L. C. Morone, Ana T. A. Sachetto, Marcelo L. Santoro, Oliver Schilling, Solange M. T. Serrano   +6 more
wiley   +1 more source

Self‐Organized Vascularized Human Liver Spheroids: Serum‐Free Culture Conditions and Use as Tissue Building Blocks

Small, Volume 22, Issue 49, 1 September 2026.
This approach addresses a major challenge in tissue engineering: creating larger, vascularized tissues. Microvascular networks in liver spheroids are developed through self‐organization mediated by mesenchymal stem cells. These spheroids are maintained in serum‐reduced or serum‐free medium and serve as building blocks to form planar tissue layers ...
Alina Filatova, Olivera Valentirović Dann, Jennifer B. Schwarzkopf, Tengku I. Maulana, Jamina S. Gerhardus, Leon Kaysan, Katja Meier, Andreas Blaeser, Beate K. Straub, Holger Gerhardt, Ulrike A. Nuber   +10 more
wiley   +1 more source

Calcium-binding properties of human fibrin(ogen) and degradation products

, 1979
Here the results obtained with human fibrinogen and its degradation products are reported. Our results differ from those obtained in (9) but strongly support model suggested earlier by us for Ca2(+)-binding by rat fibrinogen. Chemicals/CAS: calcium, 7440-
Nooijen, W.J., Nieuwenhuizen, W., Vermond, A., Haverkate, F.   +3 more
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Artificial Catch Bonds: From Molecular Design to Network Mechanics

ChemSystemsChem, Volume 8, Issue 5, September 2026.
Catch bonds strengthen rather than weaken under force. This review follows the discovery and development of our understanding of this counterintuitive phenomenon, from the molecular mechanisms that produce it to the design rules for engineering it in DNA, proteins, and polymers, and on to the collective network mechanics enabling materials that stiffen
Hengfeng Jiang, Micah Yang, Isaac T. S. Li   +2 more
wiley   +1 more source

Recalculation of calcium-binding properties of human and rat fibrin(ogen) and their degradation products

, 1981
Our previously published numbers for calcium binding sites and dissociation constants in fibrin(ogen)s of rat and man, and their plasmic degradation products were based on intuitive graphical analysis of Scatchard plots showing an upward curvature.
Nooijen, W.J., Nieuwenhuizen, W., Ruijven-Vermeer, I.A.M. van, Hermans, J.   +3 more
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Venous Thromboembolism in Severe Community‐Acquired Pneumonia at High‐Altitude Areas: Prevalence, Risk and Outcome

The Clinical Respiratory Journal, Volume 20, Issue 9, September 2026.
In hospitalized patients with SCAP at high‐altitude areas, the prevalence of VTE is unexpectedly high and may be associated with poor prognosis. Early identification of high‐risk individuals and refinement of preventive strategies are therefore necessary to improve patient outcomes.
Yuntao Zhang, Yanyan Zhang, Basang Xiao, Miao Lu, Jianghe Jia, Xingya Shi, Xiwangmu Yi, Yuanhua Yang, Na Cui   +8 more
wiley   +1 more source

Light‐Assisted 3D Printing Techniques and Photocrosslinking Strategies: Recent Advances in Musculoskeletal Tissue Engineering

Advanced Engineering Materials, Volume 28, Issue 16, 19 August 2026.
In this review, the current state of light‐assisted 3D printing as it pertains to engineering musculoskeletal tissues including bone, cartilage, skeletal muscle, tendon, and ligaments is summarized. Common printing techniques, photoreactive materials, and study design choices are compiled and reviewed.
Meagan Morgan, Bin Zhang, Roger Narayan
wiley   +1 more source

Factors influencing the structure of terminal plasmin degradation products of human fibrinogen and fibrin

, 1981
Experiments have been carried out with fibrinogen and with purified degradation products of fibrinogen and fibrin which demonstrate that the structure of D fragments obtained after prolonged plasmin digestion is influenced by several factors in the media.
Nieuwenhuizen, W., Vermond, A., Haverkate, F.   +2 more
core