Fibrinogen, Fibrin, and Fibrin Degradation Products in COVID-19
Current Drug Targets, 2022 Abstract:Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) is the highly patho-genic and highly transmissible human coronavirus that is the causative agent for the worldwide COVID-19 pandemic. COVID-19 manifests predominantly as a respiratory illness with symptoms consistent with viral pneumonia, but other organ systems (e.g., kidney, heart,
Matthew J Flick +2 more
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Effect of fibrinogen, fibrin, and fibrin degradation products on transendothelial migration of leukocytes [PDF]
Thrombosis Research, 2018 In spite of numerous studies on the involvement of fibrinogen in transendothelial migration of leukocytes and thereby inflammation, there is still no clear understanding of which fibrin(ogen) species can stimulate leukocyte transmigration. Although we have previously proposed that interaction of fibrin with the VLDL receptor (VLDLR) promotes leukocyte ...
Sergiy Yakovlev, Leonid Medved
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Influence of fibrin, fibrinogen and fibrinogen degradation products on cultured endothelial cells
Atherosclerosis, 1983 Thin films of a fibrin-agar mixture induced significant morphological changes in porcine aortic endothelial cells in vitro. The cells became spindle shaped, piled up and consequently the intercellular spaces widened. These morphological changes became more significant with higher concentrations of fibrin.
Kentaro Watanabe
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Increased plasma DR‐70 (fibrinogen‐fibrin degradation products) concentrations as a diagnostic biomarker in dogs with neoplasms [PDF]
Journal of Veterinary Internal Medicine, 2023 Background Tumor biomarkers have used widely in clinical oncology in human medicine. Only a few studies have evaluated the clinical utility of tumor biomarkers for veterinary medicine.
Chiao‐Hsu Ke +12 more
doaj +2 more sources
Chinese Medical Journal, 2015 Background: We investigated whether and to what extent the ratio between circulating fibrinogen (Fg) and its degradation products (FDP) reflects the severity of coronary artery disease (CAD) in type 2 diabetic patients.
Wei-Xin Xiong +7 more
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Detection of fibrinogen-fibrin degradation products by counterelectrophoresis [PDF]
Journal of Clinical Pathology, 1972 Counterelectrophoresis using a discontinuous buffer system permits detection of fibrinogen-fibrin degradation products (FDP) under a variety of clinical circumstances. The method is sensitive, reliable, and is easily performed using conventional equipment in any clinical laboratory assuming the responsibility for assaying fibrinogen-fibrin degradation ...
Jerome I. Brody
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National Journal of Physiology, Pharmacy and Pharmacology, 2022 Background: Although most of the COVID-19 patients presented with mild symptoms and recovered, a considerable number of cases became serious with poor prognosis in an unpredictable manner.
Aparajita Samaddar +4 more
doaj +2 more sources
Predictive Value of Fibrin Fibrinogen Degradation Products-to-Potassium Ratio for Poor Functional Outcome in Patients with Aneurysmal Subarachnoid Hemorrhage: A Retrospective Case–Control Study [PDF]
Neurocrit Care, 2023 Weida Li +12 more
openalex +2 more sources
Clarification of fibrin generation and degradation reaction processes of clot-fibrinolysis waveform in hemorrhagic disorders. [PDF]
PLoS ONEClot-fibrinolysis waveform analysis (CFWA) is an assay used to simultaneously evaluate coagulation and fibrinolysis reactions. Although the assay detected the reaction via transmittance changes, there was no evidence that the transmittance changes ...
Tomoko Matsumoto +9 more
doaj +2 more sources
Fibrin/Fibrinogen Degradation Products [PDF]
Archives of Disease in Childhood, 1970 W. S. Uttley, A. G. E. Allan, J. D. Cash
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