Results 41 to 50 of about 140,801 (205)
Fibrinogen is reportedly associated with neurodegenerative diseases (NDs), but the underlying causality remains controversial. Using Mendelian randomization (MR), this study aimed to assess the causal association between fibrinogen and Alzheimer’s ...
Hanyu Zhang, Zengyuan Zhou
doaj +1 more source
Migraine and vascular disease biomarkers: A population-based case-control study. [PDF]
Background The underpinnings of the migraine-stroke association remain uncertain, but endothelial activation is a potential mechanism. We evaluated the association of migraine and vascular disease biomarkers in a community-based population.
Ferrari, Michel D.+9 more
core +2 more sources
This study evaluated whether rotational thromboelastometry (ROTEM; Tem International GmbH, Munich, Germany) FIBTEM maximum clot firmness (MCF) can be used to predict plasma fibrinogen level in pediatric patients undergoing cardiac surgery.
Christopher F. Tirotta MD, MBA+10 more
doaj +1 more source
. Background:. It is currently unclear if fibrinogen is a risk factor for adverse events in patients receiving percutaneous coronary intervention (PCI) or merely serves as a marker of pre-existing comorbidities and other causal factors.
Ping Jiang+14 more
doaj +1 more source
Is serum fibrinogen an affirmative marker for vaginal delivery without PPH? [PDF]
Objective: This study was conducted to see whether predelivery serum fibrinogen is a positive marker for conception ending with ‘physiological’ blood loss instead of predicting PPH.
Rachna Agarwal+4 more
doaj +1 more source
Association of Factor V Secretion with Protein Kinase B Signaling in Platelets from Horses with Atypical Equine Thrombasthenia. [PDF]
BackgroundTwo congenital bleeding diatheses have been identified in Thoroughbred horses: Glanzmann thrombasthenia (GT) and a second, novel diathesis associated with abnormal platelet function in response to collagen and thrombin stimulation.Hypothesis ...
Blevins, G+4 more
core +1 more source
The Effect of Reagents Mimicking Oxidative Stress on Fibrinogen Function
Fibrinogen is one of the plasma proteins most susceptible to oxidative modification. It has been suggested that modification of fibrinogen may cause thrombotic/bleeding complications associated with many pathophysiological states of organism.
Jana Štikarová+6 more
doaj +1 more source
Coarse Grain Molecular Dynamics Simulation of Fibrin Polymerization [PDF]
Studies suggests that patients with deep vein thrombosis and diabetes often have hy-per coagulable blood plasma leading to higher chances of forming thromboembolisms by the rupture of blood clots, which may lead to stroke and death. Despite the advances in the field of blood clot formation and lysis research, the change in mechanical properties and its
arxiv +1 more source
Elevated plasma fibrinogen (Fg) levels consistently correlate with an unfavorable prognosis in various tumor patient cohorts. Within the tumor microenvironment, aberrant deposition and expression of Fg have been consistently observed, interacting with multiple cellular receptors and thereby accentuating its role as a regulator of inflammatory processes.
Xinyuan Wu+7 more
openaire +3 more sources
Blood rheology, cardiovascular risk factors, and cardiovascular disease: The West of Scotland Coronary Prevention Study [PDF]
The West of Scotland Coronary Prevention Study (WOSCOPS) showed that pravastatin reduced the risk of coronary heart disease (CHD) events in 6,595 middle-aged hypercholesterolaemic men aged 45-64 years without prior myocardial infarction followed for an ...
Ann Rumley+8 more
core +1 more source