Results 41 to 50 of about 307,220 (245)

In-depth characterization of N-glycosylation and sialic acid content in fetal and adult fibrinogen

Research and Practice in Thrombosis and Haemostasis
Background: Fetal fibrinogen is a variant present in neonates. Blood products used in neonates are tailored for adults and do not seamlessly integrate into neonatal clots.
Tana V. Palomino, Anastasia Sheridan, David C. Muddiman, Ashley C. Brown   +3 more
doaj   +1 more source

Young girl with congenital hypo-dysfibrogenemia presenting with an acute subdural haemorrhage

Asian Journal of Internal Medicine, 2023
Fibrinogen plays a pivotal role in the coagulation cascade. Inherited fibrinogen disorders are a heterogenous group that includes lack or reduced fibrinogen levels or a qualitative disorder of fibrinogen, dysfibrinogenemia.
I. N. Walmsley, D. T. E. Wijegunaratne, S. Satheeshkumar, N. Ranasinghe   +3 more
doaj   +1 more source

Determinants of fibrinogen in an Italian population suffering from claudication. Lower fibrinogen in the south compared to middle and north of Italy. The ADEP Group. [PDF]

, 1998
Prospective studies have shown that high plasma levels of fibrinogen are independently associated with the risk of cardiovascular complications. In patients suffering from peripheral vascular disease (PVD) fibrinogen has been shown to be an independent ...
A. Longoni, BASILI, Stefania, IULIANO, Luigi, M. Milani, M. Vieri, VIOLI, Francesco   +5 more
core  

Human platelet activation by Escherichia coli: roles for FcγRIIA and integrin αIIbβ3 [PDF]

, 2016
Gram-negative Escherichia coli cause diseases such as sepsis and hemolytic uremic syndrome in which thrombotic disorders can be found. Direct platelet–bacterium interactions might contribute to some of these conditions; however, mechanisms of human ...
Arman, Mònica, Cox, Dermot, Henderson, Ian R., Kerrigan, Steven W., Watson, Callum N., Watson, Steve P.   +5 more
core   +3 more sources

Modelling the association between fibrinogen concentration on admission and mortality in patients with massive transfusion after severe trauma: an analysis of a large regional database

Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine, 2018
Background The relationship between fibrinogen concentration and traumatic death has been poorly explored after severe trauma. Existing studies analysed this relationship in unselected trauma population, often considering fibrinogen concentration as a ...
Pierre Bouzat, François-Xavier Ageron, Jonathan Charbit, Xavier Bobbia, Pauline Deras, Jennifer Bas Dit Nugues, Etienne Escudier, Guillaume Marcotte, Marc Leone, Jean-Stéphane David   +9 more
doaj   +1 more source

Association of Factor V Secretion with Protein Kinase B Signaling in Platelets from Horses with Atypical Equine Thrombasthenia. [PDF]

, 2015
BackgroundTwo congenital bleeding diatheses have been identified in Thoroughbred horses: Glanzmann thrombasthenia (GT) and a second, novel diathesis associated with abnormal platelet function in response to collagen and thrombin stimulation.Hypothesis ...
Blevins, G, Norris, JW, Pombo, M, Shirley, E, Tablin, F   +4 more
core   +1 more source

Relationship between fibrinogen levels and cardiovascular events in patients receiving percutaneous coronary intervention: a large single-center study

Chinese Medical Journal, 2019
. Background:. It is currently unclear if fibrinogen is a risk factor for adverse events in patients receiving percutaneous coronary intervention (PCI) or merely serves as a marker of pre-existing comorbidities and other causal factors.
Ping Jiang, Zhan Gao, Wei Zhao, Ying Song, Xiao-Fang Tang, Jing-Jing Xu, Huan-Huan Wang, Lin Jiang, Jue Chen, Shu-Bin Qiao, Yue-Jin Yang, Run-Lin Gao, Bo Xu, Jin-Qing Yuan, Li-Min Chen   +14 more
doaj   +1 more source

Repurposing cancer drugs, batimastat and marimastat, to inhibit the activity of a group I metalloprotease from the venom of the Western Diamondback rattlesnake, Crotalus atrox [PDF]

, 2020
Snakebite envenomation causes over 140,000 deaths every year predominantly in developing countries. As a result, it is one of the most lethal neglected tropical diseases.
Bicknell, Andrew B., Lakshminarayanan, Karthik, Layfield, Harry J., Mehmi, Amita, Patel, Ketan, Ravishankar, Divyashree, Salim, Anika, Sonavane, Medha, Trim, Steven A., Vaiyapuri, Rajendran, Vaiyapuri, Sakthivel, Vallance, Thomas M., Williams, Harry F.   +12 more
core   +1 more source

Fibrinogen Concentrate for the Treatment of Thrombolysis-Associated Hemorrhage in Adult Ischemic Stroke Patients

Clinical and Applied Thrombosis/Hemostasis, 2020
In patients with ischemic stroke who receive systemic recombinant tissue plasminogen activator (rt-PA), the risk of secondary hemorrhage is 1-7%. Fibrinogen supplementation with cryoprecipitate is recommended in patients with rt-PA-associated symptomatic
Megan E. Barra PharmD, BCPS, BCCCP, Steven K. Feske MD, Katelyn W. Sylvester PharmD, BCPS, Charlene Ong MD, MPHS, Sarah E. Culbreth PharmD, BCPS, Patricia Krause PharmD, BCPS, Galen V. Henderson MD, Eva Rybak PharmD, BCPS   +7 more
doaj   +1 more source

Air temperature and inflammatory and coagulation responses in men with coronary or pulmonary disease during the winter season [PDF]

, 2010
Background and Objective Air temperature changes are associated with increased cardiovascular and respiratory risk, but the roles of inflammatory and coagulation markers are not well understood.
Breitner, Susanne, Frampton, Mark W., Hampel, Regina, Koenig, Wolfgang, Peters, Annette, Phipps, Richard P., Rückerl, Regina, Schneider, Alexandra, Wichmann, Heinz-Erich   +8 more
core   +1 more source