Alpha2-Antiplasmin Limits Fibrinolysis by Tenecteplase and Enhances Brain Injury After Reperfusion in Ischemic Stroke. [PDF]
Singh S, Saleem S, Sullivan RD, Reed GL.
europepmc +1 more source
ABSTRACT Background and Aims Long COVID, also known as post‐acute sequelae of SARS‐CoV‐2 infection (PASC), is a multisystem condition characterized by persistent symptoms that continue beyond the acute phase of infection. Growing evidence indicates that sustained immune dysregulation involving cytokine‐mediated inflammation, complement activation ...
Emmanuel Ifeanyi Obeagu
wiley +1 more source
Using evidence briefs to support future implementation planning: the case of early fibrinolysis for myocardial infarction and rehabilitation for the amputee patient in Colombia. [PDF]
Vélez M +11 more
europepmc +1 more source
SERPINE1 (PAI‐1) Regulation in Mechanotransduction‐Associated Cellular Senescence
ABSTRACT Cellular senescence is a complex biological process characterized by irreversible cell‐cycle arrest and acquisition of the senescence‐associated secretory phenotype (SASP). Beyond biochemical stress, increasing evidence indicates that mechanical cues from the extracellular microenvironment contribute to the regulation of senescence; however ...
Intan Chairun Nisa +4 more
wiley +1 more source
This study established and validated comprehensive RIs for four key thrombus biomarkers (TAT, PIC, TM, and t‐PAIC) in a Chinese population using the Hoffmann and Bhattacharya indirect methods on a large clinical dataset. The tailored RIs offer a practical tool for early detection and risk assessment of thrombotic diseases, supporting more precise and ...
Lei Zhang +3 more
wiley +1 more source
Role of Thromboelastometry in Sepsis-Induced Coagulopathy: A Narrative Review. [PDF]
Lubiewski A, Siemiński M.
europepmc +1 more source
A Beginner's Guide to Study the Role of Extracellular Vesicles in Coagulation
ABSTRACT This guide provides an overview of information that is needed to understand and study the coagulant functions of extracellular vesicles (EVs) in human body fluids. Although EV research has expanded rapidly, the physiological functions of EVs remain incompletely understood, and coagulation is one of the first biological functions that was ...
Rienk Nieuwland +3 more
wiley +1 more source
Adipokine, endocrine, and fibrinolysis-related alterations across abdominal obesity and metabolic syndrome phenotypes in young adults. [PDF]
Puhalo Sladoje D +6 more
europepmc +1 more source
Early prediction of multiple organ failure for sepsis patients based on machine learning algorithms
Abstract In recent years, there has been a notable rise in sepsis incidence leading to more multiple organ failure and higher mortality. The lack of effective treatments for sepsis highlights the importance of early prediction in preventing multiple organ failure. This study aimed to develop a model for the early prediction of multiple organ failure in
Runnan He +11 more
wiley +1 more source
Plasmin-mediated fibrinolysis is required for hematopoietic recovery after 5-FU-induced myeloablation. [PDF]
Nguyen TP +14 more
europepmc +1 more source

