Results 41 to 50 of about 131,232 (324)

A novel serine protease secreted by medicinal maggots enhances plasminogen activator-induced fibrinolysis. [PDF]

open access: yesPLoS ONE, 2014
Maggots of the blowfly Lucilia sericata are used for the treatment of chronic wounds. As haemostatic processes play an important role in wound healing, this study focused on the effects of maggot secretions on coagulation and fibrinolysis.
Mariena J A van der Plas   +9 more
doaj   +1 more source

Evaluation of coagulation activation after Rhinovirus infection in patients with asthma and healthy control subjects: an observational study [PDF]

open access: yes, 2014
Background Asthma exacerbations are frequently triggered by rhinovirus infections. Both asthma and respiratory tract infection can activate haemostasis. Therefore we hypothesized that experimental rhinovirus-16 infection and asthmatic airway inflammation
Bel, EHD   +12 more
core   +4 more sources

Fibrinolysis Shutdown in Trauma: Historical Review and Clinical Implications.

open access: yesAnesthesia and Analgesia, 2019
Despite over a half-century of recognizing fibrinolytic abnormalities after trauma, we remain in our infancy in understanding the underlying mechanisms causing these changes, resulting in ineffective treatment strategies.
H. Moore   +13 more
semanticscholar   +1 more source

Hyperfibrinolysis and fibrinolysis shutdown in patients with traumatic brain injury

open access: yesScientific Reports, 2022
Traumatic brain injury (TBI) is associated with coagulation/fibrinolysis disorders. We retrospectively evaluated 61 TBI cases transported to hospital within 1 h post-injury.
Ryuta Nakae   +9 more
doaj   +1 more source

Fibrinolysis in Dogs with Intracavitary Effusion: A Review

open access: yesAnimals, 2022
Physiologic fibrinolysis is a localized process in which stable fibrin strands are broken down by plasmin in response to thrombosis. Plasmin activation can also take place separately from the coagulation process, resulting in pathologic fibrinolysis ...
Andrea Zoia   +4 more
doaj   +1 more source

Spectrophotometric analysis of thrombolytic activity: SATA assay [PDF]

open access: yes, 2017
Introduction: Measurement of thrombolytic activity i.e. clot lysis is crucial for research and development of novel thrombolytics. It is also a key factor in assessment of the effectiveness of conventionally used thrombolytic agents in the clinic, which ...
Entekhabi, Nazila   +5 more
core   +2 more sources

Fibrin Clot Formation and Lysis in Plasma

open access: yesMethods and Protocols, 2020
Disturbance in the balance between fibrin formation and fibrinolysis can lead to either bleeding or thrombosis; however, our current routine coagulation assays are not sensitive to altered fibrinolysis.
Julie Brogaard Larsen, Anne-Mette Hvas
doaj   +1 more source

he effects of NETosis on fibrinolysis in colon cancer patients

open access: yesБюллетень сибирской медицины, 2022
Aim. To investigate formation of neutrophil extracellular traps (NETs) and their impact on fibrinolysis in patients with colon cancer.Materials and methods. The study was performed in two groups.
A. A. Parshina   +4 more
doaj   +1 more source

Guidelines on fibrinogen assays [PDF]

open access: yes, 2003
No abstract ...
Becker   +52 more
core   +1 more source

Interacting hepatic PAI-1/tPA gene regulatory pathways influence impaired fibrinolysis severity in obesity

open access: yesJournal of Clinical Investigation, 2020
Fibrinolysis is initiated by tissue-type plasminogen activator (tPA) and inhibited by plasminogen activator inhibitor 1 (PAI-1). In obese humans, plasma PAI-1 and tPA proteins are increased, but PAI-1 dominates, leading to reduced fibrinolysis and ...
Ze Zheng   +11 more
semanticscholar   +1 more source

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