Results 41 to 50 of about 80,628 (257)

Fibrin Clot Formation and Lysis in Plasma

open access: yesMethods and Protocols, 2020
Disturbance in the balance between fibrin formation and fibrinolysis can lead to either bleeding or thrombosis; however, our current routine coagulation assays are not sensitive to altered fibrinolysis.
Julie Brogaard Larsen, Anne-Mette Hvas
doaj   +1 more source

Hypofibrinolysis in type 2 diabetes and its clinical implications: from mechanisms to pharmacological modulation

open access: yesCardiovascular Diabetology, 2021
A prothrombotic state is a typical feature of type 2 diabetes mellitus (T2DM). Apart from increased platelet reactivity, endothelial dysfunction, hyperfibrinogenemia, and hypofibrinolysis are observed in T2DM.
Agata Hanna Bryk-Wiązania, Anetta Undas
doaj   +1 more source

Measuring fibrinolysis: from research to routine diagnostic assays

open access: yesJournal of Thrombosis and Haemostasis, 2018
Development and standardization of fibrinolysis methods have progressed more slowly than coagulation testing and routine high‐throughput screening tests for fibrinolysis are still lacking. In laboratory research, a variety of approaches are available and
C. Longstaff
semanticscholar   +1 more source

Percutaneous Coronary Intervention after Fibrinolysis for ST-Segment Elevation Myocardial Infarction Patients: An Updated Systematic Review and Meta-Analysis. [PDF]

open access: yesPLoS ONE, 2015
Percutaneous coronary intervention (PCI), fibrinolysis and the combination of both methods are current therapeutic options for patients with ST-segment elevation myocardial infarction (STEMI).We searched PubMed, EMBASE, Google scholar and Cochrane ...
Feng Liu   +5 more
doaj   +1 more source

Case‐only design identifies interactions of genetic risk variants at SIGLEC5 and PLG with the lncRNA CTD‐2353F22.1 implying the importance of periodontal wound healing for disease aetiology

open access: yesJournal of Clinical Periodontology, Volume 50, Issue 1, Page 90-101, January 2023., 2023
Abstract Aim The basis of phenotypic variation of periodontitis is genetic variability. Disease relevant effects of individual risk alleles are considered to result from genetic interactions. We investigated gene × gene (G×G) interactions of suggestive periodontitis susceptibility alleles.
Ricarda Müller   +6 more
wiley   +1 more source

Thrombin activatable fibrinolysis inhibitor como preditor de sangramento no transplante hepático: estudo piloto observacional

open access: yesRevista Brasileira de Terapia Intensiva
RESUMO Objetivo: Correlacionar os níveis de thrombin activatable fibrinolysis inhibitor no pós-operatório imediato e com 24 horas de pós-operatório com o volume de sangramento tansoperatório.
Wagner Luis Nedel   +2 more
doaj   +1 more source

Redefining postinjury fibrinolysis phenotypes using two viscoelastic assays

open access: yesJournal of Trauma and Acute Care Surgery, 2019
INTRODUCTION Fibrinolysis was initially defined using rapid thrombelastography (rTEG). The cutoffs for the pathologic extremes of the fibrinolytic system, hyperfibrinolysis and shutdown, were both defined based on association with mortality.
Gregory R Stettler   +6 more
semanticscholar   +1 more source

Bioactive food components and their inhibitory actions in multiple platelet pathways

open access: yesJournal of Food Biochemistry, Volume 46, Issue 12, December 2022., 2022
A comprehensive overview of platelet multifunctional roles in CVD and other diseases and the effects of food components' modulatory effects are described. Abstract In addition to hemostasis and thrombosis, blood platelets are involved in various processes such as inflammation, infection, immunobiology, cancer metastasis, wound repair and angiogenesis ...
Diptimayee Das   +7 more
wiley   +1 more source

Adrenaline May Contribute to Prothrombotic Condition via Augmentation of Platelet Procoagulant Response, Enhancement of Fibrin Formation, and Attenuation of Fibrinolysis

open access: yesFrontiers in Physiology, 2021
Background: Adrenaline is believed to play a role in thrombosis and hemostasis. The complex effect of its clinically relevant concentrations on thrombus formation, coagulation and fibrinolysis in human blood has never been specifically studied.Methods ...
Agata Golaszewska   +4 more
doaj   +1 more source

Blood clot contraction differentially modulates internal and external fibrinolysis

open access: yesJournal of Thrombosis and Haemostasis, 2019
Essentials Clot contraction influences the rate of fibrinolysis in vitro. Internal fibrinolysis is enhanced ∼2‐fold in contracted vs. uncontracted blood clots. External fibrinolysis is ∼4‐fold slower in contracted vs.
Valerie Tutwiler   +6 more
semanticscholar   +1 more source

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