Results 41 to 50 of about 127,027 (324)

Mechanical Stability and Fibrinolytic Resistance of Clots Containing Fibrin, DNA, and Histones [PDF]

open access: yes, 2013
Neutrophil extracellular traps are networks of DNA and associated proteins produced by nucleosome release from activated neutrophils in response to infection stimuli and have recently been identified as key mediators between innate immunity, inflammation,
Ammollo   +36 more
core   +1 more source

Fibrinolysis Shutdown in Trauma: Historical Review and Clinical Implications.

open access: yesAnesthesia and Analgesia, 2019
Despite over a half-century of recognizing fibrinolytic abnormalities after trauma, we remain in our infancy in understanding the underlying mechanisms causing these changes, resulting in ineffective treatment strategies.
H. Moore   +13 more
semanticscholar   +1 more source

A novel serine protease secreted by medicinal maggots enhances plasminogen activator-induced fibrinolysis. [PDF]

open access: yesPLoS ONE, 2014
Maggots of the blowfly Lucilia sericata are used for the treatment of chronic wounds. As haemostatic processes play an important role in wound healing, this study focused on the effects of maggot secretions on coagulation and fibrinolysis.
Mariena J A van der Plas   +9 more
doaj   +1 more source

Hyperfibrinolysis and fibrinolysis shutdown in patients with traumatic brain injury

open access: yesScientific Reports, 2022
Traumatic brain injury (TBI) is associated with coagulation/fibrinolysis disorders. We retrospectively evaluated 61 TBI cases transported to hospital within 1 h post-injury.
Ryuta Nakae   +9 more
doaj   +1 more source

he effects of NETosis on fibrinolysis in colon cancer patients

open access: yesБюллетень сибирской медицины, 2022
Aim. To investigate formation of neutrophil extracellular traps (NETs) and their impact on fibrinolysis in patients with colon cancer.Materials and methods. The study was performed in two groups.
A. A. Parshina   +4 more
doaj   +1 more source

Temporal Trends in Care and Outcomes of Patients Receiving Fibrinolytic Therapy Compared to Primary Percutaneous Coronary Intervention: Insights From the Get With The Guidelines Coronary Artery Disease (GWTG‐CAD) Registry

open access: yesJournal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2016
BackgroundTimely reperfusion after ST‐elevation myocardial infarction (STEMI) improves survival. Guidelines recommend primary percutaneous coronary intervention (PPCI) within 90 minutes of arrival at a PCI‐capable hospital.
Ravi S. Hira   +15 more
doaj   +1 more source

Hypofibrinolysis in type 2 diabetes and its clinical implications: from mechanisms to pharmacological modulation

open access: yesCardiovascular Diabetology, 2021
A prothrombotic state is a typical feature of type 2 diabetes mellitus (T2DM). Apart from increased platelet reactivity, endothelial dysfunction, hyperfibrinogenemia, and hypofibrinolysis are observed in T2DM.
Agata Hanna Bryk-Wiązania, Anetta Undas
doaj   +1 more source

Local fibrinolysis in surgical treatment of traumatic intracranial hemorrhage

open access: yesUkrainian Neurosurgical Journal, 2008
This review is devoted to the problem of new miniinvasive method of local fibrinolysis application in surgical treatment of traumatic intracranial hemorrhage.
K. I. Gorbatyuk, A. S. Gotin
doaj   +1 more source

Fibrin Clot Formation and Lysis in Plasma

open access: yesMethods and Protocols, 2020
Disturbance in the balance between fibrin formation and fibrinolysis can lead to either bleeding or thrombosis; however, our current routine coagulation assays are not sensitive to altered fibrinolysis.
Julie Brogaard Larsen, Anne-Mette Hvas
doaj   +1 more source

Coagulation and anticoagulation in idiopathic pulmonary fibrosis [PDF]

open access: yes, 2015
Idiopathic pulmonary fibrosis (IPF) is an incurable, progressive interstitial lung disease with a prognosis that is worse than that of many cancers. Epidemiological studies have demonstrated a link between IPF and thrombotic vascular events.
Crooks, Michael G., Hart, Simon P.
core   +3 more sources

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