Evaluation of coagulation activation after Rhinovirus infection in patients with asthma and healthy control subjects: an observational study [PDF]
Background Asthma exacerbations are frequently triggered by rhinovirus infections. Both asthma and respiratory tract infection can activate haemostasis. Therefore we hypothesized that experimental rhinovirus-16 infection and asthmatic airway inflammation
Bel, EHD+12 more
core +4 more sources
Coagulation and anticoagulation in idiopathic pulmonary fibrosis [PDF]
Idiopathic pulmonary fibrosis (IPF) is an incurable, progressive interstitial lung disease with a prognosis that is worse than that of many cancers. Epidemiological studies have demonstrated a link between IPF and thrombotic vascular events.
Crooks, Michael G., Hart, Simon P.
core +3 more sources
A novel serine protease secreted by medicinal maggots enhances plasminogen activator-induced fibrinolysis. [PDF]
Maggots of the blowfly Lucilia sericata are used for the treatment of chronic wounds. As haemostatic processes play an important role in wound healing, this study focused on the effects of maggot secretions on coagulation and fibrinolysis.
Mariena J A van der Plas+9 more
doaj +1 more source
Elevated PAI-1 is associated with poor clinical outcomes in pediatric patients with acute lung injury. [PDF]
PurposeDeposition of fibrin in the alveolar space is a hallmark of acute lung injury (ALI). Plasminogen activator inhibitor-1 (PAI-1) is an antifibrinolytic agent that is activated during inflammation. Increased plasma and pulmonary edema fluid levels of
Brady, Sandra+4 more
core +2 more sources
Hyperfibrinolysis and fibrinolysis shutdown in patients with traumatic brain injury
Traumatic brain injury (TBI) is associated with coagulation/fibrinolysis disorders. We retrospectively evaluated 61 TBI cases transported to hospital within 1 h post-injury.
Ryuta Nakae+9 more
doaj +1 more source
Fibrinolysis in Dogs with Intracavitary Effusion: A Review
Physiologic fibrinolysis is a localized process in which stable fibrin strands are broken down by plasmin in response to thrombosis. Plasmin activation can also take place separately from the coagulation process, resulting in pathologic fibrinolysis ...
Andrea Zoia+4 more
doaj +1 more source
Coagulopathy as a predictor of the effectiveness of tranexamic acid in severe blunt trauma: a multicenter retrospective study. [PDF]
Background Tranexamic acid (TXA) reduces mortality in severe trauma cases. However, the relationships between TXA administration and coagulation/fibrinolysis abnormalities are unclear.
Takahashi Y+5 more
europepmc +2 more sources
Fibrin Clot Formation and Lysis in Plasma
Disturbance in the balance between fibrin formation and fibrinolysis can lead to either bleeding or thrombosis; however, our current routine coagulation assays are not sensitive to altered fibrinolysis.
Julie Brogaard Larsen, Anne-Mette Hvas
doaj +1 more source
he effects of NETosis on fibrinolysis in colon cancer patients
Aim. To investigate formation of neutrophil extracellular traps (NETs) and their impact on fibrinolysis in patients with colon cancer.Materials and methods. The study was performed in two groups.
A. A. Parshina+4 more
doaj +1 more source