Plasma Concentrations of Tranexamic Acid in Postpartum Women After Oral Administration. [PDF]
, 2020 OBJECTIVE: To evaluate the pharmacokinetics of tranexamic acid after oral administration to postpartum women. METHODS: We conducted a single-center pharmacokinetic study at Teaching Hospital-Jaffna, Sri Lanka, on 12 healthy postpartum women who delivered
Arulkumaran, S +4 more
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Measuring fibrinolysis: from research to routine diagnostic assays
Journal of Thrombosis and Haemostasis, 2018 Development and standardization of fibrinolysis methods have progressed more slowly than coagulation testing and routine high‐throughput screening tests for fibrinolysis are still lacking. In laboratory research, a variety of approaches are available and
C. Longstaff
semanticscholar +1 more source
Thrombin-anti-thrombin levels and patency of arterio-venous fistula in patients undergoing haemodialysis compared to healthy volunteers : a prospective analysis [PDF]
, 2013 Peer reviewedPublisher ...
Brittenden, Julie +4 more
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Global coagulation assays to measure in vitro fibrinolysis
Thrombosis Update, 2021 (249/250 words): Introduction: Fibrinolysis is a critical component of hemostasis associated with poor outcomes if not treated early and effectively. Successful hemostasis management requires close fibrinolysis monitoring. The study aimed to compare the
Joao D. Dias +3 more
doaj
Revista Brasileira de Terapia IntensivaRESUMO Objetivo: Correlacionar os níveis de thrombin activatable fibrinolysis inhibitor no pós-operatório imediato e com 24 horas de pós-operatório com o volume de sangramento tansoperatório.
Wagner Luis Nedel +2 more
doaj +1 more source
Blood clot contraction differentially modulates internal and external fibrinolysis
Journal of Thrombosis and Haemostasis, 2019 Essentials Clot contraction influences the rate of fibrinolysis in vitro. Internal fibrinolysis is enhanced ∼2‐fold in contracted vs. uncontracted blood clots. External fibrinolysis is ∼4‐fold slower in contracted vs.
Valerie Tutwiler +6 more
semanticscholar +1 more source
Elevated PAI-1 is associated with poor clinical outcomes in pediatric patients with acute lung injury. [PDF]
, 2009 PurposeDeposition of fibrin in the alveolar space is a hallmark of acute lung injury (ALI). Plasminogen activator inhibitor-1 (PAI-1) is an antifibrinolytic agent that is activated during inflammation. Increased plasma and pulmonary edema fluid levels of
Brady, Sandra +4 more
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Redefining postinjury fibrinolysis phenotypes using two viscoelastic assays
Journal of Trauma and Acute Care Surgery, 2019 INTRODUCTION Fibrinolysis was initially defined using rapid thrombelastography (rTEG). The cutoffs for the pathologic extremes of the fibrinolytic system, hyperfibrinolysis and shutdown, were both defined based on association with mortality.
Gregory R Stettler +6 more
semanticscholar +1 more source
Percutaneous Coronary Intervention after Fibrinolysis for ST-Segment Elevation Myocardial Infarction Patients: An Updated Systematic Review and Meta-Analysis. [PDF]
PLoS ONE, 2015 Percutaneous coronary intervention (PCI), fibrinolysis and the combination of both methods are current therapeutic options for patients with ST-segment elevation myocardial infarction (STEMI).We searched PubMed, EMBASE, Google scholar and Cochrane ...
Feng Liu +5 more
doaj +1 more source
Journal of Clinical Medicine, 2019 A disruption of immune checkpoints leads to imbalances in immune homeostasis, resulting in immune-related adverse events. Recent case studies have suggested the association between immune checkpoint inhibitors (ICIs) and the disorders of the coagulation ...
R. Sato +15 more
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