Results 91 to 100 of about 24,629 (256)
Acute Myocardial Infarction: Molecular Pathogenesis, Diagnosis, and Clinical Management
MedComm, Volume 6, Issue 10, October 2025.Key pathogenic mechanisms in AMI. Oxidative stress and mitochondrial dysfunction induce ROS accumulation, while DAMPs‐PRRs interaction triggers inflammatory cascades. Programmed cell death pathways and epigenetic regulation collectively constitute the core components of AMI pathogenesis.
Mengmeng Zhu +5 more
wiley +1 more source
Use of intrapleural recombinant streptokinase in a pregnant woman with pleural empyema
Archivo Médico de Camagüey, 2018 Background: pneumonia complicates 0,78-2,7 per 1 000 pregnancies placing the mother and the fetus at risk. Empyema as a complication of pneumonia in a pregnant patient adds a high rate of morbidity and mortality to the mother and the fetus if one does ...
Miguel Emilio García Rodríguez +5 more
doaj
Фармация и фармакология (Пятигорск), 2019 The search and development of direct and rapid anticoagulants used per os, is an urgent problem in physiological and medical science. A number of plants contain heparin-like components with a positive effect on the hemostatic system, both within normal ...
M. G. Lyapina +3 more
doaj +1 more source
Effect of high glucose concentration on the synthesis of monocyte chemoattractant protein-1 in human peritoneal mesothelial cells: Involvement of protein kinase C [PDF]
, 2001 Human peritoneal mesothelial cells (HMC) contribute to the activation and control of inflammatory processes in the peritoneum by their potential to produce various inflammatory mediators.
Haslinger, Bettina +4 more
core +1 more source
Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, Volume 45, Issue 10, Page 677-687, October 2025.ABSTRACT Introduction Pediatric plastic bronchitis (PB) is a rare complication of surgically palliated congenital heart disease (CHD). Fibrin casts obstruct airways and can cause respiratory distress. There are no therapeutics approved by the United States Food and Drug Administration to treat PB, but inhaled tissue plasminogen activator (tPA) has been
Kathleen A. Stringer +10 more
wiley +1 more source
Asn12 and Asn278: Critical Residues for In Vitro Biological Activity of Reteplase
Advances in Hematology, 2010 Reteplase (rPA) is a thrombolytic agent used for the treatment of acute myocardial infarction. We studied the expression of rPA and its selected asparagine mutants after integration into the Pichia genome.
Naganath Mandi +4 more
doaj +1 more source
FASEB BioAdvances, Volume 7, Issue 10, October 2025.ABSTRACT Alveolar hypercoagulation and fibrinolytic inhibition are critical mechanisms contributing to refractory hypoxemia in acute respiratory distress syndrome (ARDS). The nuclear factor kappa‐B (NF‐κB) pathway is known to play a role in these processes.
Ying Liu +9 more
wiley +1 more source
Troxerutin Potentiated Temozolomide Induced Antitumor Effect in 2D and 3D Glioblastoma Models
Journal of Cellular and Molecular Medicine, Volume 29, Issue 19, October 2025.ABSTRACT Glioblastoma (GBM) is a highly aggressive brain tumour characterised by rapid proliferation and high invasiveness. Temozolomide (TMZ) is the first‐line chemotherapy, but its efficacy is often compromised by intrinsic or acquired resistance and significant side effects.
Deborah Mannino +7 more
wiley +1 more source
Pharmacotherapy Challenges of Fontan‐Associated Plastic Bronchitis: A Rare Pediatric Disease [PDF]
, 2013 Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/99662/1/phar1290 ...
Brooks, Kristina +3 more
core +1 more source
Fibrinolytic activity of Amirkabiria odoratissima Mozaffarian
Journal of Medicinal Plants, 2005 Background: fibrinolytic agents like streptokinase (SK) and urokinase (UK) are urgent treatment of thromboembolism. Besides thrombolysis, these medications have side effect like: generalized lytic state, serum fibrinogen decrease, effect on body ...
S Asgary +4 more
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