Results 21 to 30 of about 67,800 (280)

Synthesis and Bioactivities of Marine Pyran-Isoindolone Derivatives as Potential Antithrombotic Agents

Marine Drugs, 2021
2,5-Bis-[8-(4,8-dimethyl-nona-3,7-dienyl)-5,7-dihydroxy-8-methyl-3-keto-1,2,7,8-teraahydro-6H-pyran[a]isoindol-2-yl]-pentanoic acid (FGFC1) is a marine pyran-isoindolone derivative isolated from a rare marine microorganism Stachybotrys longispora FG216 ...
Yinan Wang, Hui Chen, Ruilong Sheng, Zhe Fu, Junting Fan, Wenhui Wu, Qidong Tu, Ruihua Guo   +7 more
doaj   +1 more source

Bioactive food components and their inhibitory actions in multiple platelet pathways

Journal of Food Biochemistry, Volume 46, Issue 12, December 2022., 2022
A comprehensive overview of platelet multifunctional roles in CVD and other diseases and the effects of food components' modulatory effects are described. Abstract In addition to hemostasis and thrombosis, blood platelets are involved in various processes such as inflammation, infection, immunobiology, cancer metastasis, wound repair and angiogenesis ...
Diptimayee Das, Shubhamay Adhikary, Ranjit Kumar Das, Antara Banerjee, Arun Kumar Radhakrishnan, Sujay Paul, Surajit Pathak, Asim K. Duttaroy   +7 more
wiley   +1 more source

Fibrin and Fibrinolytic Enzyme Cascade in Thrombosis: Unravelling the Role

Life, 2023
Blood clot formation in blood vessels (thrombosis) is a major cause of life-threatening cardiovascular diseases. These clots are formed by αA-, βB-, and ϒ-peptide chains of fibrinogen joined together by isopeptide bonds with the help of blood coagulation
Rajni Singh, Prerna Gautam, Chhavi Sharma, Alexander Osmolovskiy   +3 more
doaj   +1 more source

Advancements in left ventricular assist devices to prevent pump thrombosis and blood coagulopathy

Journal of Anatomy, Volume 242, Issue 1, Page 29-49, January 2023., 2023
Left ventricular assist device (LVAD)‐related blood coagulopathy: Pump thrombosis is one of the most severe adverse events caused by LVADs. The contact of blood with artificial materials of LVAD pumps and cannulas triggers the coagulation cascade. Abstract Mechanical circulatory support (MCS) devices, such as left ventricular assist devices (LVADs) are
Grainne Malone, Gerges Abdelsayed, Fianait Bligh, Fatma Al Qattan, Saifullah Syed, Prateepan Varatharajullu, Augustin Msellati, Daniela Mwipatayi, Maimoona Azhar, Andrew Malone, Saulat H. Fatimi, Claire Conway, Aamir Hameed   +12 more
wiley   +1 more source

Isolation, production and application of fibrinolytic enzyme from fermented rice, pulse and groundnut [PDF]

, 2022
Accumulation of fibrin in blood vessels usually results in thrombosis, leading to myocardial infarction and other cardiovascular disease. For Thrombolytic therapy, microbial fibrinolytic enzymes have now attracted much more attention than typical ...
Singh Shera , Shailendra, Singh, Nitika
core   +1 more source

Do children get dry socket?—The incidence and pattern of presentation of alveolar osteitis in children and adolescents following dental extractions

Oral Surgery, Volume 16, Issue 1, Page 31-40, February 2023., 2023
Abstract Background Alveolar osteitis (AO) is widely reported as the most common post‐operative complication following surgical and non‐surgical exodontia. Despite being one of the most studied complications in dentistry, there is no established consensus on its aetiology, alongside a relative paucity of studies looking exclusively into AO incidence in
Christopher C. Donnell, Megan V. Clark, Ian P. Corbett   +2 more
wiley   +1 more source

Histomorphometric analysis of the lung of Swiss mice treated with a fibrinolytic protease

Anais da Academia Brasileira de Ciências, 2022
Fibrinolytic enzymes are considered promising alternative in the treatment of cardiovascular diseases by preventing fibrin clots. A protease from Mucor subtilissimus UCP 1262 was obtained by solid state fermentation and purified by ion exchange ...
MARLLYN M. DA SILVA, MARIA A.C. DE LIRA, TAMIRIS A. ROCHA, DANIELLE F. DE MOURA, FRANCISCO C.A.A. JÚNIOR, ANA V.S. FERREIRA, LORENZO PASTRANA, WENDELL W.C. ALBUQUERQUE, ROMERO M.P.B. COSTA, THIAGO P. NASCIMENTO, ANA L.F. PORTO   +10 more
doaj   +1 more source

A Novel Marine Pyran-Isoindolone Compound Enhances Fibrin Lysis Mediated by Single-Chain Urokinase-Type Plasminogen Activator

Marine Drugs, 2022
Fungi fibrinolytic compound 1 (FGFC1) is a rare pyran-isoindolone derivative with fibrinolytic activity. The aim of this study was to further determine the effect of FGFC1 on fibrin clots lysis in vitro.
Chunli Gao, Simin Tang, Haixing Zhang, Huishu Zhang, Tian Zhang, Bin Bao, Yuping Zhu, Wenhui Wu   +7 more
doaj   +1 more source

Studies on an antifibrinolytic agent trans-AMCHA [PDF]

, 1968
Lysis of fibrin was first recognized by MORGAGNI in 1769, observing a liquid blood in a patient of acute death, and the phenomenon was named as fibrinolysis by DASTRE in 1893.
Fujiyama, Noboru, Morimoto, Setsuo, Ohmoto, Takechiyo, Shigemoto, Hirosada, Shimizu, Hiroshi, Sunada, Terutake   +5 more
core   +1 more source

Production and biochemical and biophysical characterization of fibrinolytic protease of a Mucor subtilissimus strain isolated from the caatinga biome [PDF]

Anais da Academia Brasileira de Ciências
Cardiovascular diseases, resulting from the deposition of clots in blood vessels, are the leading cause of death worldwide. Fibrinolytic enzymatic activity can catalyze blood clot degradation. Findings show that 36 fungal isolates recovered from Caatinga
AMANDA EMMANUELLE S. CONNIFF, THIAGO P. NASCIMENTO, ROMERO MARCOS P.B. COSTA, LEONID BREYDO, CAMILA S. PORTO, ATTILIO CONVERTI, JOYCE G.W. SIQUEIRA, JOSE ANTONIO TEIXEIRA, GALBA MARIA DE CAMPOS-TAKAKI, VLADIMIR N. UVERSKY, ANA LÚCIA F. PORTO, TATIANA S. PORTO   +11 more
doaj   +1 more source