Results 21 to 30 of about 24,629 (256)

A Novel Marine Pyran-Isoindolone Compound Enhances Fibrin Lysis Mediated by Single-Chain Urokinase-Type Plasminogen Activator

Marine Drugs, 2022
Fungi fibrinolytic compound 1 (FGFC1) is a rare pyran-isoindolone derivative with fibrinolytic activity. The aim of this study was to further determine the effect of FGFC1 on fibrin clots lysis in vitro.
Chunli Gao, Simin Tang, Haixing Zhang, Huishu Zhang, Tian Zhang, Bin Bao, Yuping Zhu, Wenhui Wu   +7 more
doaj   +1 more source

Bioconversion of agro-industrial wastes for the production of fibrinolytic enzyme from Bacillus halodurans IND18: Purification and biochemical characterization

Electronic Journal of Biotechnology, 2016
Background: Agro-wastes were used for the production of fibrinolytic enzyme in solid-state fermentation. The process parameters were optimized to enhance the production of fibrinolytic enzyme from Bacillus halodurans IND18 by statistical approach.
Ponnuswamy Vijayaraghavan, Samuel Gnana Prakash Vincent, Mariadhas Valan Arasu, Naif Abdullah Al-Dhabi   +3 more
doaj   +1 more source

Histomorphometric analysis of the lung of Swiss mice treated with a fibrinolytic protease

Anais da Academia Brasileira de Ciências, 2022
Fibrinolytic enzymes are considered promising alternative in the treatment of cardiovascular diseases by preventing fibrin clots. A protease from Mucor subtilissimus UCP 1262 was obtained by solid state fermentation and purified by ion exchange ...
MARLLYN M. DA SILVA, MARIA A.C. DE LIRA, TAMIRIS A. ROCHA, DANIELLE F. DE MOURA, FRANCISCO C.A.A. JÚNIOR, ANA V.S. FERREIRA, LORENZO PASTRANA, WENDELL W.C. ALBUQUERQUE, ROMERO M.P.B. COSTA, THIAGO P. NASCIMENTO, ANA L.F. PORTO   +10 more
doaj   +1 more source

Spectrophotometric analysis of thrombolytic activity: SATA assay [PDF]

, 2017
Introduction: Measurement of thrombolytic activity i.e. clot lysis is crucial for research and development of novel thrombolytics. It is also a key factor in assessment of the effectiveness of conventionally used thrombolytic agents in the clinic, which ...
Entekhabi, Nazila, Eskandani, Morteza, Farhoudi, Mehdi, Mohammadian, Reza, Rafi, Mohammad, Zamanlu, Masumeh   +5 more
core   +2 more sources

Potentiation of thrombus instability: a contributory mechanism to the effectiveness of antithrombotic medications [PDF]

, 2018
© The Author(s) 2018The stability of an arterial thrombus, determined by its structure and ability to resist endogenous fibrinolysis, is a major determinant of the extent of infarction that results from coronary or cerebrovascular thrombosis.
A Gast, AD Michelson, B Labarthe, B Shen, C Patrono, CT Ammollo, D Capodanno, D Gailani, DA Gorog, Diana A. Gorog, DM Coenen, E Álvarez, ER Bates, F Kabirian, F Müller, F Semeraro, G Stephens, H Brogren, HE Speich, HE Speich, HJ Weiss, HJ Weiss, HR Baumgartner, J Zilberman-Rudenko, JD McFadyen, JI Weitz, JM Cosemans, JP Collet, JP Collet, K Hosokawa, K Nagatsuka, KS Sakariassen, L Valerio, LF Brass, M Cattaneo, M Farag, M Humbert, M Larsson, M Li, M Ungerer, MA Bailey, MI Furman, MJ Price, ML Montfoort von, MS Sabatine, P Andre, P Seizer, PA Borne von dem, PP Wadowski, R Hellmuth, R Nergiz-Unal, RA Ajjan, S Goto, S Goto, SA Shaya, SB Larsen, SJ Marciniak, T Heitzer, T Renné, VT Turitto, VT Turitto, WA Schumacher, WS Nesbitt, X Wang, Y Yano, YC Lau, ZM Ruggeri   +66 more
core   +2 more sources

Food Origin Fibrinolytic Enzyme With Multiple Actions

Hayati Journal of Biosciences, 2018
Many health related problems such as cardiovascular diseases are associated with the formation of excessive clot in the blood (thrombus). Approaches in cardiovascular disease treatment are preventing the formation or removing the thrombus.
Laurentia Stephani, Raymond Rubianto Tjandrawinata, Diana Nur Afifah, Yanti Lim, Wangsa Tirta Ismaya, Maggy Thenawidjaja Suhartono   +5 more
doaj   +1 more source

Production and biochemical and biophysical characterization of fibrinolytic protease of a Mucor subtilissimus strain isolated from the caatinga biome [PDF]

Anais da Academia Brasileira de Ciências
Cardiovascular diseases, resulting from the deposition of clots in blood vessels, are the leading cause of death worldwide. Fibrinolytic enzymatic activity can catalyze blood clot degradation. Findings show that 36 fungal isolates recovered from Caatinga
AMANDA EMMANUELLE S. CONNIFF, THIAGO P. NASCIMENTO, ROMERO MARCOS P.B. COSTA, LEONID BREYDO, CAMILA S. PORTO, ATTILIO CONVERTI, JOYCE G.W. SIQUEIRA, JOSE ANTONIO TEIXEIRA, GALBA MARIA DE CAMPOS-TAKAKI, VLADIMIR N. UVERSKY, ANA LÚCIA F. PORTO, TATIANA S. PORTO   +11 more
doaj   +1 more source

Studies on an antifibrinolytic agent trans-AMCHA [PDF]

, 1968
Lysis of fibrin was first recognized by MORGAGNI in 1769, observing a liquid blood in a patient of acute death, and the phenomenon was named as fibrinolysis by DASTRE in 1893.
Fujiyama, Noboru, Morimoto, Setsuo, Ohmoto, Takechiyo, Shigemoto, Hirosada, Shimizu, Hiroshi, Sunada, Terutake   +5 more
core   +1 more source

Food Origin Fibrinolytic Enzyme With Multiple Actions

Hayati Journal of Biosciences, 2017
Many health related problems such as cardiovascular diseases are associated with the formation of excessive clot in the blood (thrombus). Approaches in cardiovascular disease treatment are preventing the formation or removing the thrombus.
Laurentia Stephani, Raymond Rubianto Tjandrawinata, Diana Nur Afifah, Yanti Lim, Wangsa Tirta Ismaya, Maggy Thenawidjaja Suhartono   +5 more
doaj   +1 more source

Assessing the effectiveness of primary angioplasty compared with thrombolysis and its relationship to time delay: a Bayesian evidence synthesis [PDF]

, 2007
Background: Meta-analyses of trials have shown greater benefits from angioplasty than thrombolysis after an acute myocardial infarction, but the time delay in initiating angioplasty needs to be considered.
Abrams, Keith R., Asseburg, Christian, de Belder, Mark, Fenwick, Elisabeth, Palmer, Stephen, Sculpher, Mark, Vergel, Yolanda Bravo   +6 more
core   +4 more sources