Results 41 to 50 of about 24,629 (256)

Elevated PAI-1 is associated with poor clinical outcomes in pediatric patients with acute lung injury. [PDF]

, 2009
PurposeDeposition of fibrin in the alveolar space is a hallmark of acute lung injury (ALI). Plasminogen activator inhibitor-1 (PAI-1) is an antifibrinolytic agent that is activated during inflammation. Increased plasma and pulmonary edema fluid levels of
Brady, Sandra, Curley, Martha AQ, Flori, Heidi, Matthay, Michael A, Sapru, Anil   +4 more
core   +2 more sources

Using Tenecteplase for Acute Ischemic Stroke: What Is the Hold Up? [PDF]

, 2020
Alteplase is the only Food and Drug Administration-approved intravenous (IV) thrombolytic medication for acute ischemic stroke. However, multiple recent studies comparing tenecteplase and alteplase suggest that tenecteplase is at least as efficacious as ...
Ataya, Ramsey, Brea, Isabel, Zitek, Tony
core  

Cessation of dual antiplatelet therapy and cardiovascular events following acute coronary syndrome [PDF]

, 2019
Objective: To assess whether cardiovascular events are increased after cessation of dual antiplatelet therapy (DAPT) following acute coronary syndrome (ACS) and to explore predictors for recurrent events after DAPT cessation during long-term follow-up.
Berry, Colin, Dawson, Jesse, Mazlan-Kepli, Wardati, Walters, Matthew   +3 more
core   +1 more source

Hypofibrinolysis in diabetes: a therapeutic target for the reduction of cardiovascular risk [PDF]

, 2017
An enhanced thrombotic environment and premature atherosclerosis are key factors for the increased cardiovascular risk in diabetes. The occlusive vascular thrombus, formed secondary to interactions between platelets and coagulation proteins, is composed ...
A Agren, A Ceriello, A Hamsten, A Hamsten, A Lados-Krupa, A Liang, A Lutjens, A Rouch, A Rupin, A Sahebkar, A Tripodi, A Undas, A Undas, A Undas, AH Guimaraes, AH Henschen-Edman, AH Straten van, AS Wolberg, AS Wolberg, B Blomback, B Craen Van De, B Lipinski, B Rocca, B Wiman, B Zinman, BH Shieh, C Longstaff, CH Lundgren, CH Nair, CL Nikolajsen, CS Fox, D Capodanno, D Hill, D Leenaerts, D Ricklin, DA Gabriel, DA Lawrence, DA Lawrence, Darren Tomlinson, DJ Schneider, DL Crandall, DV Sakharov, E Angelantonio Di, E Chow, E Ernst, E Pretorius, E Pretorius, E Shacter, E Vercauteren, EG Levin, EJ Dunn, EJ Dunn, EL Hethershaw, EM Sherif, F Denorme, F Rollini, G Boden, G Gajos, G Jorneskog, GJ Brouwers, GK Hansson, GL Booth, GL Reed 3rd, GL Reed 3rd, H Elokdah, H Ritchie, HC Gerstein, HH Versteeg, HJ Beijers, HK Kim, I Juhan-Vague, I Shimomura, J Bester, J Danesh, J Montaner, J Svensson, J Weisel, JA Dormandy, JC Chapin, JD Mills, JG Dillinger, JH Foley, JL Ferreiro, JL Mega, JM Howes, JP Collet, JP Collet, JW Weisel, K Bangert, K Buelens, K Distelmaier, K Fatah, K Hess, K Hess, K Hess, K Leander, K Leander, Katherine Kearney, KE Brummel, Kerrie Smith, KN Lee, KN Lee, KN Lee, KN Lee, KN Lee, KR Machlus, L Badimon, L Ryden, L Wallentin, LM Belalcazar, M Konieczynska, M Pieters, M Pieters, M Pieters, M Rigla, M Udvardy, MA Bailey, MB Kahn, MC Alessi, ME Carr Jr, ME Meltzer, ME Meltzer, ME Meltzer, ME Stegenga, MG Marini, MR Hammer, MS Ardawi, N Gogitidze Joy, N Zheng, NH Tilburg van, NV Gorlatova, O Sigurdardottir, OJ Phung, P Chudy, P Clemmensen, P Katz, P Kohli, P Soma, P Soma, R Ajjan, R Favier, R King, RA Ajjan, RA Ajjan, RA Al-Horani, Ramzi Ajjan, RM Cubbon, RM Missov, RP Rother, RR Holman, S James, S Kimura, S Kimura, S Neergaard-Petersen, S Schulman, S Tehrani, S Tehrani, S Yener, SD Wiviott, SD Wiviott, SH Alzahrani, SH Alzahrani, SJ Cleland, SK Kunutsor, SL Carpenter, SP Marso, SR Fraser, ST Lord, T Koyama, T Kumada, T Lisman, T Plug, T Sasaki, T Tamaki, T Wyseure, T Wyseure, TC Holten van, TW Meade, U Amara, V Baeriswyl, VR Richardson, WB Kannel, X Zhou, X Zhou, Y Hori, Y Sakata, Y Sakata, Y Sakata, Y Sumi, Y Yano, YM Fortenberry, Z Valnickova   +191 more
core   +2 more sources

Comparison of the methods of fibrinolysis by tube thoracostomy and thoracoscopic decortication in children with stage II and III empyema: a prospective randomized study

Pediatric Reports, 2011
Today, in spite of the developments in imaging methods and antibiotherapy, childhood pleural empyema is a prominent cause of morbidity and mortality. In recent years, it has been shown that there has been an increase in the frequency of pleural empyema ...
Ufuk Cobanoglu, Fuat Sayir, Salim Bilici, Mehmet Melek   +3 more
doaj   +1 more source

Inhibitors in Patients with Congenital Bleeding Disorders Other Than Hemophilia [PDF]

, 2017
The most worrying complication of replacement therapy for severe hemophilia A and B is currently the occurrence of inhibitory alloantibodies against infused factor VIII and factor IX, respectively.
Franchini, Massimo, Liumbruno, Giancarlo Maria, Marano, Giuseppe, Mengoli, Carlo, Piccinini, Vanessa, Pupella, Simonetta, Vaglio, Stefania   +6 more
core   +1 more source

Expression of recombinant staphylokinase in the methylotrophic yeast Hansenula polymorpha

BMC Biotechnology, 2012
Background Currently, the two most commonly used fibrinolytic agents in thrombolytic therapy are recombinant tissue plasminogen activator (rt-PA) and streptokinase (SK).
Moussa Manal, Ibrahim Mahmoud, El Ghazaly Maria, Rohde Jan, Gnoth Stefan, Anton Andreas, Kensy Frank, Mueller Frank   +7 more
doaj   +1 more source

Role of intrapleural instillation of MESNA in the management of pleural adhesions

Egyptian Journal of Chest Disease and Tuberculosis, 2022
Context Intrapleural adhesions and pleural fluid loculation is a common clinical problem. Several options are available to manage the intrapleural adhesions. MESNA has recently been used as a fibrinolytic agent and due to its efficacy and safety it is an
Amany Omar, Abd-Elazim Abo Elfadl, Yousef Ahmed, Hussein Elkhayat, Montaser Gamal   +4 more
doaj   +1 more source

ST-Elevation myocardial infarction network: systematization in 205 cases reduced clinical events in the public health care system [PDF]

, 2012
BACKGROUND: The major cause of death in the city of São Paulo (SP) is cardiac events. At its periphery, in-hospital mortality in acute myocardial infarction is estimated to range between 15% and 20% due to difficulties inherent in large metropoles ...
Alves, Claudia Maria Rodrigues, Barbosa, Adriano H., Caluza, Ana Christina Vellozo, Carvalho, Antonio Carlos, Gonçalves, Iran, Matos, Lívia Nascimento de, Moreno, Antonio Célio C., Oliveira, Carlos Alexandre L. de, Tarkieltaub, Elcio, Zeefried, Claus   +9 more
core   +3 more sources

An Injectable Zwitterionic Hydrogels with Multiple Intermolecular Interactions for Effective Prevention of Abdominal Adhesions

Advanced Science, EarlyView.
An injectable PSA‐ZnO through multiple intermolecular including hydrogen bonds and electrostatic interactions for effectively prevents abdominal adhesions. The PSA‐ZnO hydrogel demonstrates superior wound healing promotion (≥ 95%) and more effective inhibition of scar formation compared to the commercial 3M dressing (≈80%), and prevents post‐operative ...
Na Wen, Yating Jiang, Yunhao Song, Jiachao Yang, Jinlin Long, Ying Wang, Xunbin Yu, Shiyun Lu, Tianhua Zhou, Xueping Huang   +9 more
wiley   +1 more source